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English
Effect of ligand binding on the flexibility of dihydrofolate reductase as revealed by compressibility
scientific article published on 01 May 2000
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10825537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10825537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
title
Effect of ligand binding on the flexibility of dihydrofolate reductase as revealed by compressibility
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10825537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10825537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
T Kamiyama
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10825537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10825537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
K Gekko
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10825537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10825537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
language of work or name
English
0 references
publication date
1 May 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10825537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10825537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
number of pages
10
1 reference
based on heuristic
inferred from page(s)
published in
Biochimica et Biophysica Acta
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10825537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10825537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
1478
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10825537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10825537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10825537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10825537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
257-266
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10825537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10825537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
cites work
Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of multiple replacements at a single position on the folding and stability of dihydrofolate reductase from Escherichia coli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-range electrostatic interactions can influence the folding, stability, and cooperativity of dihydrofolate reductase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transient intermediates in the folding of dihydrofolate reductase as detected by far-ultraviolet circular dichroism spectroscopy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dihydrofolate reductase: multiple conformations and alternative modes of substrate binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for two interconverting protein isomers in the methotrexate complex of dihydrofolate reductase from Escherichia coli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamics of the dihydrofolate reductase-folate complex: catalytic sites and regions known to undergo conformational change exhibit diverse dynamical features
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impact on catalysis of secondary structural manipulation of the alpha C-helix of Escherichia coli dihydrofolate reductase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a functional role of the dynamics of glycine-121 of Escherichia coli dihydrofolate reductase obtained from kinetic analysis of a site-directed mutant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of point mutation in a flexible loop on the stability and enzymatic function of Escherichia coli dihydrofolate reductase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Point mutations at glycine-121 of Escherichia coli dihydrofolate reductase: important roles of a flexible loop in the stability and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of point mutations at the flexible loop glycine-67 of Escherichia coli dihydrofolate reductase on its stability and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of point mutations at the flexible loop alanine-145 of Escherichia coli dihydrofolate reductase on its stability and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonadditive effects of double mutations at the flexible loops, glycine-67 and glycine-121, of Escherichia coli dihydrofolate reductase on its stability and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The internal dynamics of globular proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thermodynamic fluctuations in protein molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Compressibility-structure relationship of globular proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The hydration of globular proteins as derived from volume and compressibility measurements: cross correlating thermodynamic and structural data
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Compactness of thermally and chemically denatured ribonuclease A as revealed by volume and compressibility
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Volumetric Characterizations of the Native, Molten Globule and Unfolded States of Cytochromecat Acidic pH
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Partial volumes and compressibilities of extended polypeptide chains in aqueous solution: additivity scheme and implication of protein unfolding at normal and high pressure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adiabatic compressibility of myoglobin. Effect of axial ligand and denaturation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of tightly bound substrates in pure preparations of dihydrofolate reductase: implications for studies on enzymes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Internal cavities and buried waters in globular proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Functional Role for Protein Cavities in Domain:Domain Motions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Some factors in the interpretation of protein denaturation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Implications for enzymic catalysis from free-energy reaction coordinate profiles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4838%2800%2900019-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0167-4838(00)00019-4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10825537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10825537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PubMed publication ID
10825537
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10825537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10825537%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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