(Q73877878)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9368516%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

The impact of high-risk patients on the results of clinical trials (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9368516%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

author name string

J P Ioannidis

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9368516%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

J Lau

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9368516%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

publication date

1 October 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9368516%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Epidemiology

7 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9368516%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

volume

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9368516%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9368516%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

page(s)

1089-1098

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9368516%20AND%20SRC:MED&resulttype=core&format=json

Generalizing the results of randomized clinical trials

7 November 2019

cites work

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7 January 2021

Can overall results of clinical trials be applied to all patients?

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7 January 2021

Staging system for clinical AIDS patients

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7 January 2021

Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversion

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7 January 2021

Prognosis in HIV-1 infection predicted by the quantity of virus in plasma

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https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Viral counts count in HIV infection

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https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection

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https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

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7 January 2021

Importance of age at infection with HIV-1 for survival and development of AIDS in UK haemophilia population. UK Haemophilia Centre Directors' Organisation

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7 January 2021

A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 cell counts from 200 to 500 per cubic millimeter. AIDS Clinical Trials Group Study 175 Study Team

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7 January 2021

Combination and monotherapy with zidovudine and zalcitabine in patients with advanced HIV disease. The NIAID AIDS Clinical Trials Group

1 reference

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7 January 2021

Early or deferred zidovudine therapy in HIV-infected patients without an AIDS-defining illness.

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Concorde trial of immediate versus deferred zidovudine

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Beneficial effects of intravenous immunoglobulins in AIDS

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

A dose-ranging study of daily maintenance intravenous foscarnet therapy for cytomegalovirus retinitis in AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Clarithromycin therapy for bacteremic Mycobacterium avium complex disease. A randomized, double-blind, dose-ranging study in patients with AIDS. AIDS Clinical Trials Group Protocol 157 Study Team

1 reference

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7 January 2021

Clarithromycin and ethambutol with or without clofazimine for the treatment of bacteremic Mycobacterium avium complex disease in patients with HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Effects of high-dose oral acyclovir on herpesvirus disease and survival in patients with advanced HIV disease: a double-blind, placebo-controlled study. European-Australian Acyclovir Study Group

1 reference

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7 January 2021

Lower survival in AIDS patients receiving dapsone compared with aerosolized pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia. Study Group

1 reference

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7 January 2021

Virologic and immunologic benefits of initial combination therapy with zidovudine and zalcitabine or didanosine compared with zidovudine monotherapy. Wellcome Resistance Study Collaborative Group

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Trimetrexate with leucovorin versus trimethoprim-sulfamethoxazole for moderate to severe episodes of Pneumocystis carinii pneumonia in patients with AIDS: a prospective, controlled multicenter investigation of the AIDS Clinical Trials Group Protocol

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Comparison of atovaquone (566C80) with trimethoprim-sulfamethoxazole to treat Pneumocystis carinii pneumonia in patients with AIDS

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Primary prophylaxis with pyrimethamine for toxoplasmic encephalitis in patients with advanced human immunodeficiency virus disease: results of a randomized trial. Terry Beirn Community Programs for Clinical Research on AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Mortality in patients with the acquired immunodeficiency syndrome treated with either foscarnet or ganciclovir for cytomegalovirus retinitis

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

A controlled trial of early adjunctive treatment with corticosteroids for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. California Collaborative Treatment Group

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

A comparison of two regimens for the treatment of Mycobacterium avium complex bacteremia in AIDS: rifabutin, ethambutol, and clarithromycin versus rifampin, ethambutol, clofazimine, and ciprofloxacin. Canadian HIV Trials Network Protocol 010 Study G

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

A randomized trial of clarithromycin as prophylaxis against disseminated Mycobacterium avium complex infection in patients with advanced acquired immunodeficiency syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Corticosteroids as adjunctive therapy for severe Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

The efficacy and safety of zidovudine alone or as cotherapy with acyclovir for the treatment of patients with AIDS and AIDS-related complex: a double-blind randomized trial. European-Australian Collaborative Group

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Cholesterol lowering and mortality: the importance of considering initial level of risk

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

An evidence based approach to individualising treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

An effect model for the assessment of drug benefit: example of antiarrhythmic drugs in postmyocardial infarction patients

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Controversies in meta-analysis: the case of the trials of serum cholesterol reduction

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

The population risk as an explanatory variable in research synthesis of clinical trials.

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Effects of intravenous magnesium in suspected acute myocardial infarction: overview of randomised trials

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Intravenous magnesium sulphate in suspected acute myocardial infarction: results of the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2)

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Misleading meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Mega-trials and management of acute myocardial infarction.

1 reference

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7 January 2021

Predictors of 30-day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. GUSTO-I Investigators

1 reference

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7 January 2021

Cumulative meta-analysis of therapeutic trials for myocardial infarction

1 reference

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7 January 2021

Randomized trials of magnesium in acute myocardial infarction: big numbers do not tell the whole story.

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Infarct size and magnesium: insights into LIMIT-2 and ISIS-4 from experimental studies.

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

An experimental model examining the role of magnesium in the therapy of acute myocardial infarction

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Magnesium Sulfate Reduces Myocardial Infarct Size When Administered Before but Not After Coronary Reperfusion in a Canine Model

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Timing of Magnesium Therapy Affects Experimental Infarct Size

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

The recent decline in mortality from coronary heart disease, 1980-1990. The effect of secular trends in risk factors and treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

21 year trends in incidence of myocardial infarction and mortality from coronary disease in middle-age

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Difference in countries' use of resources and clinical outcome for patients with cardiogenic shock after myocardial infarction: results from the GUSTO trial

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Large trials vs meta-analysis of smaller trials: how do their results compare?

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

Impact of epidemic and individual heterogeneity on the population distribution of disease progression rates. An example from patient populations in trials of human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS0895-4356%2897%2900149-2

7 January 2021

10.1016/S0895-4356(97)00149-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9368516%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference