(Q73894187)

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Microsomal triglyceride transfer protein binding and lipid transfer activities are independent of each other, but both are required for secretion of apolipoprotein B lipoproteins from liver cells

scientific article published on 17 May 2001

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11358959%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Microsomal triglyceride transfer protein binding and lipid transfer activities are independent of each other, but both are required for secretion of apolipoprotein B lipoproteins from liver cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11358959%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

author name string

Liang J

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11358959%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Ginsberg HN

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11358959%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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publication date

17 May 2001

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11358959%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Journal of Biological Chemistry

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11358959%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

276

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11358959%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

30

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11358959%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

28606-28612

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11358959%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Purification and characterization of microsomal triglyceride and cholesteryl ester transfer protein from bovine liver microsomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Localization of intracellular triacylglycerol and cholesteryl ester transfer activity in rat tissues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Protein disulfide isomerase appears necessary to maintain the catalytically active structure of the microsomal triglyceride transfer protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

The amino terminus of apolipoprotein B is necessary but not sufficient for microsomal triglyceride transfer protein responsiveness

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Microsomal triglyceride transfer protein: a protein complex required for the assembly of lipoprotein particles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Co-translational degradation of apolipoprotein B100 by the proteasome is prevented by microsomal triglyceride transfer protein. Synchronized translation studies on HepG2 cells treated with an inhibitor of microsomal triglyceride transfer protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Regulated Co-translational ubiquitination of apolipoprotein B100. A new paradigm for proteasomal degradation of a secretory protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed ham

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

apoB-100 has a pentapartite structure composed of three amphipathic alpha-helical domains alternating with two amphipathic beta-strand domains. Detection by the computer program LOCATE.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Apolipoprotein B sequence requirements for hepatic very low density lipoprotein assembly. Evidence that hydrophobic sequences within apolipoprotein B48 mediate lipid recruitment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Translocation efficiency, susceptibility to proteasomal degradation, and lipid responsiveness of apolipoprotein B are determined by the presence of beta sheet domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Demonstration of a physical interaction between microsomal triglyceride transfer protein and apolipoprotein B during the assembly of ApoB-containing lipoproteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Interactions between microsomal triglyceride transfer protein and apolipoprotein B within the endoplasmic reticulum in a heterologous expression system.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Amino acids 430-570 in apolipoprotein B are critical for its binding to microsomal triglyceride transfer protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Lysine and arginine residues in the N-terminal 18% of apolipoprotein B are critical for its binding to microsomal triglyceride transfer protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

The structure of vitellogenin provides a molecular model for the assembly and secretion of atherogenic lipoproteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

A common binding site on the microsomal triglyceride transfer protein for apolipoprotein B and protein disulfide isomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Identification of cysteine pairs within the amino-terminal 5% of apolipoprotein B essential for hepatic lipoprotein assembly and secretion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Functional analysis of disulfide linkages clustered within the amino terminus of human apolipoprotein B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Apoprotein B100 has a prolonged interaction with the translocon during which its lipidation and translocation change from dependence on the microsomal triglyceride transfer protein to independence.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

The degradation of apolipoprotein B100 is mediated by the ubiquitin-proteasome pathway and involves heat shock protein 70

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Cell and molecular biology of the assembly and secretion of apolipoprotein B-containing lipoproteins by the liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Decreased secretion of ApoB follows inhibition of ApoB-MTP binding by a novel antagonist

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100294200

21 January 2018

Identifiers

10.1074/JBC.M100294200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11358959%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11358959%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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