(Q73911228)

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A systematic approach to the validation of process control parameters for monoclonal antibody production in fed-batch culture of a murine myeloma

scientific article published on 01 August 2000

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7 November 2019

A systematic approach to the validation of process control parameters for monoclonal antibody production in fed-batch culture of a murine myeloma (English)

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7 November 2019

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E B Moran

1

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7 November 2019

S T McGowan

2

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7 November 2019

J M McGuire

3

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7 November 2019

J E Frankland

4

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7 November 2019

I A Oyebade

5

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7 November 2019

W Waller

6

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7 November 2019

L C Archer

7

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7 November 2019

L O Morris

8

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7 November 2019

J Pandya

9

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7 November 2019

S R Nathan

10

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7 November 2019

L Smith

11

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7 November 2019

M L Cadette

12

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7 November 2019

J T Michalowski

13

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7 November 2019

publication date

1 August 2000

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7 November 2019

Biotechnology and Bioengineering

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7 November 2019

69

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7 November 2019

3

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7 November 2019

242-255

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7 November 2019

Effect of temperature on nucleotide pools and monoclonal antibody production in a mouse hybridoma.

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Monoclonal antibody process development using medium concentrates

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Ammonia affects the glycosylation patterns of recombinant mouse placental lactogen-I by chinese hamster ovary cells in a pH-dependent manner

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

The effect of the removal of sialic acid, galactose and total carbohydrate on the functional activity of Campath-1H

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Glycosylation of recombinant protein therapeutics: control and functional implications

1 reference

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21 January 2018

Monitoring recombinant human interferon-gamma N-glycosylation during perfused fluidized-bed and stirred-tank batch culture of CHO cells

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Relationship between hybridoma growth and monoclonal antibody production.

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Influence of low temperature on productivity, proteome and protein phosphorylation of CHO cells

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Dissolved oxygen concentration in serum-free continuous culture affects N-linked glycosylation of a monoclonal antibody.

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Glycosylation and biological activity of CAMPATH-1H expressed in different cell lines and grown under different culture conditions

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Effect of bench-scale culture conditions on murine IgG heterogeneity

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: effect of nutrient concentration, dilution rate, and pH.

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Loss of antibody productivity during long-term cultivation of a hybridoma cell line in low serum and serum-free media

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Growth, metabolic, and antibody production kinetics of hybridoma cell culture: 2. Effects of serum concentration, dissolved oxygen concentration, and medium pH in a batch reactor

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Isolation, characterization and recombinant protein expression in Veggie-CHO: A serum-free CHO host cell line

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Characterization of a recombinant antibody produced in the course of a high yield fed-batch process

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Rapid, sensitive sequencing of oligosaccharides from glycoproteins

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Criteria for investigation of the product equivalence of monoclonal antibodies for therapeutic and in vivo-diagnostic use in case of introduction of changes in the manufacturing process

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

The influence of temperature on a mouse-mouse hybridoma growth and monoclonal antibody production

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Comparison of N-linked oligosaccharides of recombinant human tissue kallikrein produced by Chinese hamster ovary cells on microcarrier beads and in serum-free suspension culture

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Effect of glycosylation on antibody function: implications for genetic engineering

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Bicarbonate concentration and osmolality are key determinants in the inhibition of CHO cell polysialylation under elevated pCO2 or pH

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Fed-batch culture of recombinant NS0 myeloma cells with high monoclonal antibody production

1 reference

https://api.crossref.org/works/10.1002%2F1097-0290%2820000805%2969%3A3%3C242%3A%3AAID-BIT2%3E3.0.CO%3B2-I

21 January 2018

Identifiers

10.1002/1097-0290(20000805)69:3<242::AID-BIT2>3.0.CO;2-I

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10861404%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10861404%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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