(Q73955694)

English

Binding of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex to the endocytosis receptors alpha2-macroglobulin receptor/low-density lipoprotein receptor-related protein and very-low-density lipoprotein receptor involves

scientific article published on 01 January 1998

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405275%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Binding of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex to the endocytosis receptors alpha2-macroglobulin receptor/low-density lipoprotein receptor-related protein and very-low-density lipoprotein receptor involves basic residues in the inhibitor (English)

1 reference

Europe PubMed Central

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8 November 2019

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author name string

K W Rodenburg

1

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Europe PubMed Central

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8 November 2019

L Kjoller

2

1 reference

Europe PubMed Central

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8 November 2019

H H Petersen

3

1 reference

Europe PubMed Central

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8 November 2019

P A Andreasen

4

1 reference

Europe PubMed Central

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8 November 2019

publication date

1 January 1998

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8 November 2019

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405275%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

329 ( Pt 1)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405275%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

55-63

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405275%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Type-1 plasminogen-activator inhibitor -- conformational differences between latent, active, reactive-centre-cleaved and plasminogen-activator-complexed forms, as probed by proteolytic susceptibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activators, tissue degradation, and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator inhibitors: hormonally regulated serpins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of residues in alpha-macroglobulins important for binding to the alpha2-macroglobulin receptor/Low density lipoprotein receptor-related protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies to human 54,000 molecular weight plasminogen activator inhibitor from fibrosarcoma cells--inhibitor neutralization and one-step affinity purification

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzyme-linked immunosorbent assay for human urokinase-type plasminogen activator and its proenzyme using a combination of monoclonal and polyclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cDNA cloning of human plasminogen activator-inhibitor from endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator inhibitor type-1: reactive center and amino-terminal heterogeneity determined by protein and cDNA sequencing.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational and immunochemical analysis of plasminogen activator inhibitor 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WHAT IF: a molecular modeling and drug design program

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the target specificity of plasminogen activator inhibitor 1: the role of heparin, vitronectin, and the reactive site

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serpin tertiary structure transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type-1 inhibitor of plasminogen activators. Distinction between latent, activated and reactive centre-cleaved forms with thermal stability and monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis of latency in plasminogen activator inhibitor-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Internalization of the urokinase-plasminogen activator inhibitor type-1 complex is mediated by the urokinase receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elucidation of structural requirements on plasminogen activator inhibitor 1 for binding to heparin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The urokinase-type plasminogen activator system in cancer metastasis: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping of binding sites for heparin, plasminogen activator inhibitor-1, and plasminogen to vitronectin's heparin-binding region reveals a novel vitronectin-dependent feedback mechanism for the control of plasmin formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interconversions between active, inert and substrate forms of denatured/refolded type-1 plasminogen activator inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor-mediated endocytosis of plasminogen activators and activator/inhibitor complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of vitronectin binding domain in plasminogen activator inhibitor-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease nexin-1-urokinase complexes are internalized and degraded through a mechanism that requires both urokinase receptor and alpha 2-macroglobulin receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The alpha 2-macroglobulin receptor and epithelial glycoprotein-330: two giant receptors mediating endocytosis of multiple ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of the vitronectin binding site on plasminogen activator inhibitor 1 (PAI‐1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regions involved in binding of urokinase-type-1 inhibitor complex and pro-urokinase to the endocytic alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that the urokinase receptor protects pro-urokinase against

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The multiligand alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein (alpha 2MR/LRP). Binding and endocytosis of fluid phase and membrane-associated ligands.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Very low density lipoprotein receptor from mammary gland and mammary epithelial cell lines binds and mediates endocytosis of M(r) 40,000 receptor associated protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP).

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model of the reactive form of plasminogen activator inhibitor-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

What do dysfunctional serpins tell us about molecular mobility and disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase/urokinase receptor system: internalization/degradation of urokinase-serpin complexes: mechanism and regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LDL receptor-related protein: a multiligand receptor for lipoprotein and proteinase catabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arg-27, Arg-127 and Arg-155 in the beta-trefoil protein barley alpha-amylase/subtilisin inhibitor are interface residues in the complex with barley alpha-amylase 2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Very low density lipoprotein receptor binds and mediates endocytosis of urokinase-type plasminogen activator-type-1 plasminogen activator inhibitor complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of urokinase-type-1 inhibitor complex endocytosis by phorbol esters in different cell lines is associated with differential regulation of alpha 2-macroglobulin receptor and urokinase receptor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms contributing to the conformational and functional flexibility of plasminogen activator inhibitor-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serpin-protease complexes are trapped as stable acyl-enzyme intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of a vitronectin binding region of plasminogen activator inhibitor-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-2 Macroglobulin receptor/Ldl receptor-related protein(Lrp)-dependent internalization of the urokinase receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition mechanism of serpins. Evidence that the mobile reactive center loop is cleaved in the native protease-inhibitor complex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular internalization and degradation of antithrombin III-thrombin, heparin cofactor II-thrombin, and alpha 1-antitrypsin-trypsin complexes is mediated by the low density lipoprotein receptor-related protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator inhibitor-1 and vitronectin promote the cellular clearance of thrombin by low density lipoprotein receptor-related proteins 1 and 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biostructural pathology of the serpins: critical function of sheet opening mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Segments in the C-terminal folding domain of lipoprotein lipase important for binding to the low density lipoprotein receptor-related protein and to heparan sulfate proteoglycans

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular internalization and degradation of thrombospondin-1 is mediated by the amino-terminal heparin binding domain (HBD). High affinity interaction of dimeric HBD with the low density lipoprotein receptor-related protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator inhibitor-1 represses integrin- and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of serine proteinase/serpin complex binding to very-low-density lipoprotein receptor and alpha2-macroglobulin receptor/low-density-lipoprotein-receptor-related protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9405275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3290055

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405275%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405275%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9405275%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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