(Q73958365)

English

Design, synthesis and structure-affinity relationships of 4-methylidenepiperidine and 4-aryl-1,2,3,6-tetrahydropyridine derivatives as corticotropin-releasing factor1 receptor antagonists

scientific article published on 01 May 2000

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10882028%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Design, synthesis and structure-affinity relationships of 4-methylidenepiperidine and 4-aryl-1,2,3,6-tetrahydropyridine derivatives as corticotropin-releasing factor1 receptor antagonists (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10882028%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

author name string

A Nakazato

1

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10882028%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

T Kumagai

2

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10882028%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

T Okubo

3

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10882028%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

H Tanaka

4

1 reference

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8 November 2019

S Chaki

5

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8 November 2019

S Okuyama

6

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10882028%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

K Tomisawa

7

1 reference

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8 November 2019

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1 May 2000

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8 November 2019

Bioorganic & Medicinal Chemistry

1 reference

Europe PubMed Central

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8 November 2019

8

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8 November 2019

5

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8 November 2019

1183-1193

1 reference

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8 November 2019

Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

1 reference

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Mediation by corticotropin releasing factor (CRF) of adenohypophysial hormone secretion

1 reference

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7 January 2021

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Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

1 reference

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Corticotropin-releasing factor (CRF) and endocrine responses to stress: CRF receptors, binding protein, and related peptides

1 reference

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7 January 2021

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Expression cloning of a human corticotropin-releasing-factor receptor

1 reference

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7 January 2021

based on heuristic

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Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor

1 reference

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7 January 2021

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Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain.

1 reference

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7 January 2021

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Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain.

1 reference

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7 January 2021

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Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

1 reference

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7 January 2021

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Corticotropin-releasing hormone

1 reference

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7 January 2021

based on heuristic

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Synthesis and oral efficacy of a 4-(butylethylamino)pyrrolo[2,3-d]pyrimidine: a centrally active corticotropin-releasing factor1 receptor antagonist.

1 reference

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7 January 2021

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inferred from DOI database lookup

CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors.

1 reference

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7 January 2021

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A non peptidic corticotropin releasing factor receptor antagonist attenuates fever and exhibits anxiolytic-like activity

1 reference

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7 January 2021

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Antidepressant-like effects of CP-154,526, a selective CRF1 receptor antagonist.

1 reference

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7 January 2021

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CP-154,526, a selective, non-peptide antagonist of the corticotropin-releasing factor1 receptor attenuates stress-induced relapse to drug seeking in cocaine- and heroin-trained rats

1 reference

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7 January 2021

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Rapid microscale synthesis, a new method for lead optimization using robotics and solution phase chemistry: application to the synthesis and optimization of corticotropin-releasing factor1 receptor antagonists

1 reference

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7 January 2021

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Design and synthesis of a series of non-peptide high-affinity human corticotropin-releasing factor1 receptor antagonists

1 reference

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7 January 2021

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Non-peptide corticotropin-releasing hormone antagonists: syntheses and structure-activity relationships of 2-anilinopyrimidines and -triazines

1 reference

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7 January 2021

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Corticotropin-releasing hormone receptor antagonists: framework design and synthesis guided by ligand conformational studies

1 reference

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7 January 2021

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Synthesis, corticotropin-releasing factor receptor binding affinity, and pharmacokinetic properties of triazolo-, imidazo-, and pyrrolopyrimidines and -pyridines

1 reference

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7 January 2021

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Corticotropin-releasing factor receptors are widely distributed within the rat central nervous system: an autoradiographic study

1 reference

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7 January 2021

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In vitro pharmacological profile of nonpeptide CRF1 receptor antagonists, CRA1000 and CRA1001

1 reference

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7 January 2021

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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Identifiers

10.1016/S0968-0896(00)00045-6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10882028%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10882028%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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