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Genotoxicity of several clinically used topoisomerase II inhibitors
scientific article published on 01 July 2000
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10906417
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906417%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
title
Genotoxicity of several clinically used topoisomerase II inhibitors
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10906417
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906417%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
main subject
genotoxicity
1 reference
based on heuristic
inferred from title
author name string
G Boos
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10906417
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906417%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
H Stopper
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10906417
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906417%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
publication date
1 July 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10906417
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906417%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
published in
Toxicology Letters
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10906417
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906417%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
volume
116
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10906417
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906417%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
issue
1-2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10906417
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906417%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
page(s)
7-16
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10906417
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906417%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
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Genotoxicity of inhibitors of DNA topoisomerases I (camptothecin) and II (m-AMSA) in vivo and in vitro
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Human 170 kDa and 180 kDa topoisomerases II bind preferentially to curved and left-handed linear DNA.
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Etoposide: current status and future perspectives in the management of malignant neoplasms
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7 January 2021
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DNA binding properties of minor groove binders and their influence on the topoisomerase II cleavage reaction
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reference URL
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7 January 2021
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Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme
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In vitro evolution of preferred topoisomerase II DNA cleavage sites
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The use of L5178Y mouse lymphoma cells to assess the mutagenic, clastogenic and aneugenic properties of chemicals.
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When good enzymes go bad: conversion of topoisomerase II to a cellular toxin by antineoplastic drugs
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Antitumour Activity in a Series of bisDiketopiperazines
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7 January 2021
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Mitoxantrone affects topoisomerase activities in human breast cancer cells
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Crossref
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7 January 2021
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Mutagenicity of m-AMSA and o-AMSA in mammalian cells due to clastogenic mechanism: possible role of topoisomerase
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7 January 2021
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Micronucleus, chromosome aberration, and small-colony TK mutant analysis to quantitate chromosomal damage in L5178Y mouse lymphoma cells
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Induction of petite mutants in yeast by non-intercalative DNA-binding antitumour agents
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7 January 2021
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Hypothesis: some mutagens directly alter specific chromosomal proteins (DNA topoisomerase II and peripheral proteins) to produce chromosome stickiness, which causes chromosome aberrations
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Interactions of Drosophila DNA topoisomerase II with left-handed Z-DNA in supercoiled minicircles
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Etoposide (VP16) and teniposide (VM26): novel anticancer drugs, strongly mutagenic in mammalian but not prokaryotic test systems.
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7 January 2021
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Clinical applications of anticancer drugs targeted to topoisomerase II
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Drosophila topoisomerase II-DNA interactions are affected by DNA structure
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7 January 2021
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DNA topoisomerases.
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Crossref
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7 January 2021
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Analysis of micronuclei induced in mouse early spermatids by mitomycin C, vinblastine sulfate or etoposide using fluorescence in situ hybridization
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Binding of etoposide to topoisomerase II in the absence of DNA: decreased affinity as a mechanism of drug resistance
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Induction of micronuclei, DNA strand breaks and HPRT mutations in cultured Chinese hamster V79 cells by the phytoestrogen coumoestrol
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The phytoestrogens coumoestrol and genistein induce structural chromosomal aberrations in cultured human peripheral blood lymphocytes
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7 January 2021
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Genotoxicity of the laxative drug components emodin, aloe-emodin and danthron in mammalian cells: topoisomerase II mediated?
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Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide
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Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: inhibition of DNA religation by etoposide.
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Catalytic function of DNA topoisomerase II.
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7 January 2021
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Differential sensitivities of recombinant human topoisomerase IIalpha and beta to various classes of topoisomerase II-interacting agents
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7 January 2021
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Berenil acts as a poison of eukaryotic topoisomerase II
1 reference
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Crossref
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7 January 2021
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DNA minor groove binding agents interfere with topoisomerase II mediated lesions induced by epipodophyllotoxin derivative VM-26 and acridine derivative m-AMSA in nuclei from L1210 cells
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reference URL
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7 January 2021
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Induction of micronucleus formation in mouse splenocytes by the soy isoflavone genistein in vitro but not in vivo
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of antineoplastic drugs on the post-strand-passage DNA cleavage/religation equilibrium of topoisomerase II.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stabilization of the topoisomerase II-DNA cleavage complex by antineoplastic drugs: inhibition of enzyme-mediated DNA religation by 4'-(9-acridinylamino)methanesulfon-m-anisidide.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Secondary acute myeloid leukemia in children previously treated with alkylating agents, intercalating topoisomerase II inhibitors, and irradiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
A simple technique for quantitation of low levels of DNA damage in individual cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Therapy-related acute myeloid leukemia following treatment with epipodophyllotoxins: estimating the risks
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation events
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Eating to beat breast cancer: potential role for soy supplements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Micronuclei as a biological endpoint for genotoxicity: A minireview.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-cycle dependent micronucleus formation and mitotic disturbances induced by 5-azacytidine in mammalian cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Analogues of 1,5-bis(4-amidinophenoxy)pentane (pentamidine) in the treatment of experimental Pneumocystis carinii pneumonia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The mutagenic properties of DNA minor-groove binding ligands
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA topoisomerases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of mammalian topoisomerase II dependent DNA cleavage by nonintercalative flavonoids, genistein and orobol
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-4274%2800%2900192-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0378-4274(00)00192-2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10906417
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906417%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
PubMed publication ID
10906417
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10906417
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906417%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
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