(Q74063639)

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Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models

scientific article published on 01 November 1997

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9434879%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9434879%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

apoptotic process

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DNA mismatch repair

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B Kaina

1

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8 November 2019

A Ziouta

2

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8 November 2019

K Ochs

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9434879%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

T Coquerelle

4

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8 November 2019

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1 November 1997

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8 November 2019

Mutation Research

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9434879%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

381

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8 November 2019

2

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8 November 2019

227-241

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8 November 2019

Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents

1 reference

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7 January 2021

Removal of O6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines.

1 reference

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7 January 2021

Human tumor cell strains defective in the repair of alkylation damage.

1 reference

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7 January 2021

Suppression of human DNA alkylation-repair defects by Escherichia coli DNA-repair genes

1 reference

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7 January 2021

Transfer of the E. coli O6-methylguanine methyltransferase gene into repair-deficient human cells and restoration of cellular resistance to N-methyl-N'-nitro-N-nitrosoguanidine.

1 reference

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7 January 2021

Expression in mammalian cells of a truncated Escherichia coli gene coding for O6-alkylguanine alkyltransferase reduces the toxic effects of alkylating agents.

1 reference

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7 January 2021

Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents

1 reference

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7 January 2021

Expression of human O6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells and restoration of cellular resistance to certain N-nitroso compounds.

1 reference

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7 January 2021

The role of O6-alkylguanine in cell killing and mutagenesis in Chinese hamster ovary cells.

1 reference

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7 January 2021

Reduction of the toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene

1 reference

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7 January 2021

The prevention of thymic lymphomas in transgenic mice by human O6-alkylguanine-DNA alkyltransferase

1 reference

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7 January 2021

O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis

1 reference

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7 January 2021

The relationship between O6-alkylguanine alkyltransferase activity and sensitivity to alkylation-induced sister chromatid exchanges in human lymphoblastoid cell lines.

1 reference

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7 January 2021

Chinese hamster cells harbouring the Escherichia coli O6-alkylguanine alkyltransferase gene are less susceptible to sister chromatid exchange induction and chromosome damage by methylating agents

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

Contribution of O6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: new insights gained from studies of genetically engineered mammalian cell lines

1 reference

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7 January 2021

Importance of the DNA repair enzyme O6-alkyl guanine alkyltransferase (AT) in cancer chemotherapy.

1 reference

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7 January 2021

Increasing DNA repair methyltransferase levels via bone marrow stem cell transduction rescues mice from the toxic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a chemotherapeutic alkylating agent

1 reference

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7 January 2021

DNA synthesis with methylated poly(dC-dG) templates. Evidence for a competitive nature to miscoding by

1 reference

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7 January 2021

Mechanism of mutagenesis by O6-methylguanine

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome

1 reference

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7 January 2021

Dependency of the yield of sister-chromatid exchanges induced by alkylating agents on fixation time. Possible involvement of secondary lesions in sister-chromatid exchange induction

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

Mismatch binding proteins and tolerance to alkylating agents in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

Self-destruction and tolerance in resistance of mammalian cells to alkylation damage

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

N-Methyl-N'-nitro-N-nitrosoguanidine sensitivity of E. coli mutants deficient in DNA methylation and mismatch repair

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

Mismatch correction at O 6 -methylguanine residues in E. coli DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

A hPMS2 mutant cell line is defective in strand-specific mismatch repair

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

Mismatch G-T binding activity and MSH2 expression is quantitatively related to sensitivity of cells to methylating agents.

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

Quantitation of DNA fragmentation in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

Chapter 4 Quantification of Apoptotic Events in Pure and Heterogeneous Populations of Cells Using the Flow Cytometer

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

New Giemsa method for the differential staining of sister chromatids

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2897%2900187-5

7 January 2021

Chromosome aberrations: persistence of alkylation damage and modulation by O6-alkylguanine-DNA alkyltransferase

1 reference

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7 January 2021

Nitrosated urea pesticide metabolites and other nitrosamides. Activity in clastogenicity and SCE assays, and aberration kinetics in Chinese hamster V79-E cells

1 reference

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7 January 2021

A role for mismatch repair in production of chromosome aberrations by methylating agents in human cells

1 reference

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7 January 2021

Streptozotocin-induced genotoxic effects in Chinese hamster cells: the resistant phenotype of V79 cells

1 reference

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7 January 2021

On the quantitative relationship between O6-methylguanine residues in genomic DNA and production of sister-chromatid exchanges, mutations and lethal events in a Mer- human tumor cell line

1 reference

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7 January 2021

The intracellular signal for induction of resistance to alkylating agents in E. coli.

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7 January 2021

Apurinic sites as mutagenic intermediates

1 reference

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7 January 2021

Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents--a case of imbalanced DNA repair

1 reference

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7 January 2021

Streptozotocin-induced toxicity in CHO-9 and V79 cells

1 reference

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7 January 2021

Sister chromatid exchange

1 reference

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7 January 2021

Analyses of bromodeoxyuridine-associated sister chromatid exchanges (SCEs) in Bloom syndrome based on cell fusion: single and twin SCEs in endoreduplication

1 reference

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7 January 2021

c-Fos is involved in the cellular defence against the genotoxic effect of UV radiation

1 reference

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7 January 2021

Requirement of mammalian DNA polymerase-beta in base-excision repair.

1 reference

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7 January 2021

Repair of DNA containing O6-alkylguanine

1 reference

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7 January 2021

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10.1016/S0027-5107(97)00187-5

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9434879%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9434879%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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