(Q74178224)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9464485%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

DNA cleavage and 8-hydroxydeoxyguanosine formation caused by tamoxifen derivatives in vitro (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9464485%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

T Okubo

1

1 reference

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9 November 2019

F Nagai

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9464485%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

K Ushiyama

3

1 reference

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9 November 2019

Y Yokoyama

4

1 reference

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9 November 2019

S Ozawa

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9464485%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

K Kano

6

1 reference

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9 November 2019

S Tomita

7

1 reference

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9 November 2019

H Kubo

8

1 reference

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9 November 2019

I Kano

9

1 reference

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9 November 2019

language of work or name

English

0 references

publication date

1 January 1998

1 reference

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9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9464485%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

122

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9464485%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

1-2

1 reference

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9 November 2019

page(s)

9-15

1 reference

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Fourteenth Gaddum Memorial Lecture. A current view of tamoxifen for the treatment and prevention of breast cancer

9 November 2019

cites work

1 reference

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7 January 2021

Tamoxifen for breast cancer prevention

1 reference

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7 January 2021

The triphenylethylene drug tamoxifen is a strong liver carcinogen in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Tamoxifen induces hepatocellular carcinoma in rat liver: a 1-year study with two antiestrogens

1 reference

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7 January 2021

Descriptive clinicopathologic study of 17 patients with endometrial cancer during or after adjuvant tamoxifen in early breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Genotoxic potential of tamoxifen and analogues in female Fischer F344/n rats, DBA/2 and C57BL/6 mice and in human MCL-5 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Clastogenic and aneugenic effects of tamoxifen and some of its analogues in hepatocytes from dosed rats and in human lymphoblastoid cells transfected with human P450 cDNAs (MCL-5 cells).

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

DNA adduct formation by tamoxifen with rat and human liver microsomal activation systems

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Tamoxifen: evidence by 32P-postlabeling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA adduct formation and identification of 4-hydroxytamoxifen as a proximate metabolite.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Activation of 4-hydroxytamoxifen and the tamoxifen derivative metabolite E by uterine peroxidase to form DNA adducts: comparison with DNA adducts formed in the uterus of Sprague-Dawley rats treated with tamoxifen.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Activation of tamoxifen and its metabolite α-hydroxytamoxifen to DNA-binding products: comparisons between human, rat and mouse hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

A mechanistic hypothesis for DNA adduct formation by tamoxifen following hepatic oxidative metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Conformational studies and electronic structures of tamoxifen and toremifene and their allylic carbocations proposed as reactive intermediates leading to DNA adduct formation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Peroxidase activation of tamoxifen and toremifene resulting in DNA damage and covalently bound protein adducts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Peroxidase activation of 4-hydroxytamoxifen to free radicals detected by EPR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Production of 8-hydroxy-2'-deoxguanosine in DNA by microsomal activation of tamoxifen and 4-hydroxytamoxifen

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Contribution of oxygen radicals to DNA cleavage by quinone compounds derived from phenolic antioxidants, tert-butylhydroquinone and 2,5-di-tert-butylhydroquinone

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

Formation of 8-hydroxydeoxyguanosine in calf thymus DNA treated in vitro with phenylhydroquinone, the major metabolite of O-phenylphenol.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

DNA cleavage by phenylhydroquinone: the major metabolite of a fungicide o-phenylphenol

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

A study of the structural basis of the carcinogenicity of tamoxifen, toremifene and their metabolites

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2897%2900359-5

7 January 2021

10.1016/S0304-3835(97)00359-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9464485%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference