(Q74189016)

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A protocol for the in vitro micronucleus test. I. Contributions to the development of a protocol suitable for regulatory submissions from an examination of 16 chemicals with different mechanisms of action and different levels of activity

scientific article published on 01 May 2002

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9 November 2019

A protocol for the in vitro micronucleus test. I. Contributions to the development of a protocol suitable for regulatory submissions from an examination of 16 chemicals with different mechanisms of action and different levels of activity (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12034314%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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Michael L Garriott

1

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9 November 2019

J Barry Phelps

2

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9 November 2019

Wherly P Hoffman

3

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9 November 2019

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1 May 2002

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9 November 2019

Mutation Research

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9 November 2019

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9 November 2019

1-2

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9 November 2019

123-134

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9 November 2019

Evaluation of the in vitro micronucleus test as an alternative to the in vitro chromosomal aberration assay: position of the GUM Working Group on the in vitro micronucleus test. Gesellschaft für Umwelt-Mutations-forschung

1 reference

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7 January 2021

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Report from the In Vitro Micronucleus Assay Working Group

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7 January 2021

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ICH-harmonised guidances on genotoxicity testing of pharmaceuticals: evolution, reasoning and impact.

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7 January 2021

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Clastogenicity of 1-nitropyrene, dinitropyrenes, fluorene and mononitrofluorenes in cultured Chinese hamster cells

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7 January 2021

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Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test

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7 January 2021

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Chemically-induced unscheduled DNA synthesis in primary rat hepatocyte cultures: a comparison with bacterial mutagenicity using 218 compounds.

1 reference

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7 January 2021

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A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures

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7 January 2021

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A comparison of the CHO/HGPRT+ and the L5178Y/TK+/- mutation assays using suspension treatment and soft agar cloning: results for 10 chemicals.

1 reference

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7 January 2021

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The genetic toxicology of 6-mercaptopurine

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7 January 2021

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Re-evaluation of 1,2-dimethylhydrazine in the mouse bone marrow micronucleus assay: observation of a positive response

1 reference

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7 January 2021

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Slide preparation and sampling as a major source of variability in the mouse micronucleus assay

1 reference

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7 January 2021

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Measurement of micronuclei in lymphocytes

1 reference

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7 January 2021

based on heuristic

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Use of the cytokinesis-block method for the analysis of micronuclei in V79 Chinese hamster lung cells: results with mitomycin C and cyclophosphamide

1 reference

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7 January 2021

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Chemically induced micronucleus formation in V79 cells--comparison of three different test approaches

1 reference

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7 January 2021

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Measurement of micronuclei by cytokinesis-block method in cultured Chinese hamster cells: comparison with types and rates of chromosome aberrations

1 reference

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7 January 2021

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Induction of micronuclei and anaphase aberrations by cytochalasin B in human lymphocyte cultures

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7 January 2021

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Cytokinesis-block micronucleus assay with kinetochore detection in colchicine-treated human fibroblasts

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7 January 2021

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Evaluation of the micronucleus test in vitro using chinese hamster cells: Results of four chemicals weakly positive in the in vivo micronucleus test

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7 January 2021

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Validation study of the in vitro micronucleus test in a Chinese hamster lung cell line (CHL/IU).

1 reference

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7 January 2021

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A mathematical model of the in vitro micronucleus assay predicts false negative results if micronuclei are not specifically scored in binucleated cells or in cells that have completed one nuclear division

1 reference

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7 January 2021

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Identifiers

10.1016/S1383-5718(02)00059-1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12034314%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12034314%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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