(Q74254054)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Restoration of correct splicing of thalassemic beta-globin pre-mRNA by modified U1 snRNAs (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

Gorman L

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Mercatante DR

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Kole R

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

language of work or name

English

0 references

publication date

1 November 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

9 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

35914-35919

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

Molecular mechanisms of antisense drugs: RNase H.

9 November 2019

cites work

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Antisense oligonucleotides specific for the HER2/neu oncogene inhibit the growth of human breast carcinoma cells that overexpress HER2/neu

21 January 2018

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Antisense therapy of hepatitis B virus infection

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C-myc antisense oligodeoxynucleotides can induce apoptosis and down-regulate Fas expression in rheumatoid synoviocytes

21 January 2018

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A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease

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Uptake and efflux of intact antisense phosphorothioate deoxyoligonucleotide directed against angiotensin receptors in bovine adrenal cells

21 January 2018

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Comparison of the antiviral efficacy of ribozymes and antisense RNA directed against bovine leukemia virus rex/tax

21 January 2018

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The antisense sequence of the HIV-1 TAR stem-loop structure covalently linked to the hairpin ribozyme enhances its catalytic activity against two artificial substrates

21 January 2018

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Inhibition of human immunodeficiency virus type 1 replication by nuclear chimeric anti-HIV ribozymes in a human T lymphoblastoid cell line

21 January 2018

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Targeted cleavage of RNA molecules by human RNase P using minimized external guide sequences

21 January 2018

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Nuclease-resistant external guide sequence-induced cleavage of target RNA by human ribonuclease P.

21 January 2018

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Short oligonucleotides as external guide sequences for site-specific cleavage of RNA molecules with human RNase P.

21 January 2018

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Stable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAs

21 January 2018

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Expression of small, therapeutic RNAs in human cell nuclei.

21 January 2018

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Evaluation of the use of antisense tRNA(met) as an inhibitor for eukaryotic protein synthesis

21 January 2018

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Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides

21 January 2018

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Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides

21 January 2018

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Antisense oligonucleotides with different backbones. Modification of splicing pathways and efficacy of uptake

21 January 2018

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Sensitivity of splice sites to antisense oligonucleotides in vivo.

21 January 2018

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Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides

21 January 2018

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Specific removal of the nonsense mutation from the mdx dystrophin mRNA using antisense oligonucleotides.

21 January 2018

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21 January 2018

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3' end processing of mouse histone pre-mRNA: evidence for additional base-pairing between U7 snRNA and pre-mRNA

21 January 2018

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Multiple processing-defective mutations in a mammalian histone pre-mRNA are suppressed by compensatory changes in U7 RNA both in vivo and in vitro

21 January 2018

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Compensatory mutations suggest that base-pairing with a small nuclear RNA is required to form the 3' end of H3 messenger RNA

21 January 2018

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Isolation of an active gene and of two pseudogenes for mouse U7 small nuclear RNA

21 January 2018

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Direct selection for mutations affecting specific splice sites in a hamster dihydrofolate reductase minigene

21 January 2018

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Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

21 January 2018

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The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: causes and consequences

21 January 2018

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Alternative poly(A) site selection in complex transcription units: means to an end?

21 January 2018

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Spliceosome assembly in yeast

21 January 2018

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Inhibition of Herpes Simplex Virus Replication by Antisense Oligo-2'-O-methylribonucleoside Methylphosphonates

21 January 2018

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Antiviral effect of an oligo(nucleoside methylphosphonate) complementary to the splice junction of herpes simplex virus type 1 immediate early pre-mRNAs 4 and 5.

21 January 2018

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Inhibition of viral growth by an alpha-oligonucleotide directed to the splice junction of herpes simplex virus type-1 immediate-early pre-mRNA species 22 and 47.

21 January 2018

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Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides

21 January 2018

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U1 small nuclear RNAs with altered specificity can be stably expressed in mammalian cells and promote permanent changes in pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006259200

A compensatory base change in U1 snRNA suppresses a 5' splice site mutation

21 January 2018

1 reference

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Suppression of mammalian 5' splice-site defects by U1 small nuclear RNAs from a distance

21 January 2018

1 reference

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Double-target antisense U7 snRNAs promote efficient skipping of an aberrant exon in three human beta-thalassemic mutations

21 January 2018

1 reference

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U1 small nuclear RNA chimeric ribozymes with substrate specificity for the Rev pre-mRNA of human immunodeficiency virus

21 January 2018

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Inhibition of fibrillin 1 expression using U1 snRNA as a vehicle for the presentation of antisense targeting sequence

21 January 2018

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In vivo generation of highly abundant sequence-specific oligonucleotides for antisense and triplex gene regulation

21 January 2018

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Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter

21 January 2018

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U4 and U6 RNAs coexist in a single small nuclear ribonucleoprotein particle

21 January 2018

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Localization of a base-paired interaction between small nuclear RNAs U4 and U6 in intact U4/U6 ribonucleoprotein particles by psoralen cross-linking

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M006259200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference