(Q74302745)

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Mitochondrial free calcium levels (Rhod-2 fluorescence) and ultrastructural alterations in neuronally differentiated PC12 cells during ceramide-dependent cell death

scientific article published on 01 October 2000

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10 November 2019

Mitochondrial free calcium levels (Rhod-2 fluorescence) and ultrastructural alterations in neuronally differentiated PC12 cells during ceramide-dependent cell death (English)

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10 November 2019

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Frédéric Darios

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10 November 2019

Etienne C. Hirsch

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10 November 2019

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M P Muriel

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10 November 2019

N Lambeng

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10 November 2019

P P Michel

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10 November 2019

Y Agid

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10 November 2019

M Ruberg

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1 October 2000

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10 November 2019

The Journal of Comparative Neurology

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10 November 2019

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10 November 2019

297-315

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10 November 2019

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10 November 2019

Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function

1 reference

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Function and activation of NF-kappa B in the immune system

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21 January 2018

The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal

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Developmental cell death: morphological diversity and multiple mechanisms

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21 January 2018

Mitochondrial free radical signal in ceramide-dependent apoptosis: a putative mechanism for neuronal death in Parkinson's disease.

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21 January 2018

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

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21 January 2018

Ceramide Induces CytochromecRelease from Isolated Mitochondria

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21 January 2018

Electron-dense endoplasmic reticulum-like profiles closely associated with mitochondria in glomus cells of the carotid body after fixation with oxalate

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21 January 2018

Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide

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21 January 2018

The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.

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21 January 2018

Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease

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21 January 2018

Induction of apoptotic DNA fragmentation and cell death by natural ceramide

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21 January 2018

pRb and the cdks in apoptosis and the cell cycle

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21 January 2018

Dihydroceramide biology. Structure-specific metabolism and intracellular localization

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21 January 2018

Regulation of ceramide production and apoptosis

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21 January 2018

Elevation of intracellular glucosylceramide levels results in an increase in endoplasmic reticulum density and in functional calcium stores in cultured neurons.

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21 January 2018

The mitochondrial death/life regulator in apoptosis and necrosis

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21 January 2018

Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis

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21 January 2018

Modulation of endoplasmic reticulum calcium pump by Bcl-2.

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21 January 2018

Mechanisms of apoptosis in PC12 cells irreversibly differentiated with nerve growth factor and cyclic AMP.

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21 January 2018

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

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21 January 2018

Calcium, free radicals and excitotoxins in neuronal apoptosis.

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21 January 2018

Activation of the Bcl-2 promoter by nerve growth factor is mediated by the p42/p44 MAPK cascade

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The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

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21 January 2018

Apoptosis. Key to the mitochondrial gate

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21 January 2018

Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose.

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21 January 2018

Synergistic differentiation by chronic exposure to cyclic AMP and nerve growth factor renders rat phaeochromocytoma PC12 cells totally dependent upon trophic support for survival

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21 January 2018

An ultrastructural and immunohistochemical study of PC12 cells during apoptosis induced by serum deprivation with special reference to autophagy and lysosomal cathepsins

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21 January 2018

Diversity and complexity of ceramide signalling in apoptosis

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A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor

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21 January 2018

Disturbances of the functioning of endoplasmic reticulum: a key mechanism underlying neuronal cell injury?

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The role of ceramide in cell signaling

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Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition.

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21 January 2018

Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis

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Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses

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Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity.

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21 January 2018

Is the cell death pathway triggered by the mitochondrion or the endoplasmic reticulum?

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DEDD, a novel death effector domain-containing protein, targeted to the nucleolus

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Glutamate-induced neuron death requires mitochondrial calcium uptake

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21 January 2018

The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

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21 January 2018

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

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The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis.

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Bcl-2 interrupts the ceramide-mediated pathway of cell death.

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Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis

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Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

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21 January 2018

The mitochondrial permeability transition.

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21 January 2018

Identifiers

10.1002/1096-9861(20001016)426:2<297::AID-CNE10>3.0.CO;2-O

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10982470%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10982470%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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