(Q74339196)

English

Brain-derived neurotrophic factor-mediated neuroprotection of adult rat retinal ganglion cells in vivo does not exclusively depend on phosphatidyl-inositol-3'-kinase/protein kinase B signaling

scientific article published on 01 September 2000

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Brain-derived neurotrophic factor-mediated neuroprotection of adult rat retinal ganglion cells in vivo does not exclusively depend on phosphatidyl-inositol-3'-kinase/protein kinase B signaling (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

retinal ganglion cell

1 reference

based on heuristic

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author name string

N Klöcker

1

1 reference

Europe PubMed Central

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10 November 2019

P Kermer

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

J H Weishaupt

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

M Labes

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

R Ankerhold

5

1 reference

Europe PubMed Central

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10 November 2019

M Bähr

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

publication date

1 September 2000

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

20

1 reference

Europe PubMed Central

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10 November 2019

18

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

6962-6967

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular signals and reversible protein phosphorylation: what to Mek of it all.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in BDNF and neurotrophin receptor expression in degenerating and regenerating rat retinal ganglion cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling pathways and survival effects of BDNF and NT-3 on cultured cerebellar granule cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction via the MAP kinases: proceed at your own RSK.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases: killer proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular signaling pathways activated by neurotrophic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raf revealed in life-or-death decisions

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

At least two mechanisms are involved in the death of retinal ganglion cells following target ablation in neonatal rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influences of peripheral nerve grafts on the survival and regrowth of axotomized retinal ganglion cells in adult rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both the neuronal and inducible isoforms contribute to upregulation of retinal nitric oxide synthase activity by brain-derived neurotrophic factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mitogen-activated protein kinase and p70S6 kinase is not correlated with cerebellar granule cell survival.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated mRNA expression of brain-derived neurotrophic factor in retinal ganglion cell layer after optic nerve injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitogen-activated protein kinase signal transduction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of target tissue in regulating the development of retinal ganglion cells in the albino rat: effects of kainate lesions in the superior colliculus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A redox-triggered ras-effector interaction. Recruitment of phosphatidylinositol 3'-kinase to Ras by redox stress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor-I protects axotomized rat retinal ganglion cells from secondary death via PI3-K-dependent Akt phosphorylation and inhibition of caspase-3 In vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term effect of inhibition of ced 3-like caspases on the survival of axotomized retinal ganglion cells in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free radical scavenging and inhibition of nitric oxide synthase potentiates the neurotrophic effects of brain-derived neurotrophic factor on axotomized retinal ganglion cells In vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal ganglion cells lose trophic responsiveness after axotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of MAP kinase in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic factors and their receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of caspase-3 in axotomized rat retinal ganglion cells in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of phosphatidylinositol-3 kinase in prevention of low K(+)-induced apoptosis of cerebellar granule neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in adult retinal ganglion cells after axotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiology of the neurotrophins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linking extracellular survival signals and the apoptotic machinery

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PI3K: downstream AKTion blocks apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/10995840

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.20-18-06962.2000

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10995840%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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