(Q74403161)

English

Zinc inhibits the nuclear translocation of the tumor suppressor protein p53 and protects cultured human neurons from copper-induced neurotoxicity

scientific article published on 01 January 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095159%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Zinc inhibits the nuclear translocation of the tumor suppressor protein p53 and protects cultured human neurons from copper-induced neurotoxicity (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095159%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

based on heuristic

inferred from title

toxic encephalopathy

1 reference

based on heuristic

inferred from title

author name string

Jacob W VanLandingham

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095159%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Cheryl A Fitch

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095159%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Cathy W Levenson

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095159%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

publication date

1 January 2002

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095159%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

NeuroMolecular Medicine

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095159%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095159%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095159%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

171-182

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095159%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

https://scigraph.springernature.com/pub.10.1385/nmm:1:3:171

0 references

Expression of the p53 tumor suppressor gene is up-regulated by depletion of intracellular zinc in HepG2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of [2,3-butanedione bis(N4-dimethylthiosemicarbazone)]zinc (Zn-ATSM2)-induced protection of cultured hippocampal neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential changes of bax, caspase-3 and p21 mRNA expression after transient focal brain ischemia in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular zinc fluxes and the regulation of apoptosis/gene-directed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoic acid activates p53 in human embryonal carcinoma through retinoid receptor-dependent stimulation of p53 transactivation function

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of hsp70 synthesis induced by cupric sulfate and zinc sulfate in thermotolerant HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zinc and brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytoarchitectonic distribution of zinc in the hippocampus of man and the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preferential Zn2+ influx through Ca2+-permeable AMPA/kainate channels triggers prolonged mitochondrial superoxide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anatomical methods in cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of marginal zinc status in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zinc stimulates DNA synthesis during its antiapoptotic action independently with increments of an antiapoptotic protein, Bcl-2, in porcine kidney LLC-PK(1) cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of zinc-induced neuronal death in primary cultures of rat cerebellar granule cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of copper in neurodegenerative disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antioxidant properties of zinc: interactions with iron and antioxidants

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of zinc in the central nervous system: the zinc-containing neuron

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes of copper-transporting proteins and ceruloplasmin in the lentiform nuclei in primary adult-onset dystonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical determination of the Wilson Copper-transporting P-type ATPase in the brain tissues of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1/Fas) mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of radiocopper in the diagnosis of Wilson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A reappraisal of the role of zinc in life and death decisions of cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of intracellular free zinc concentrations accompanying zinc-induced neuronal death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA strand scission and PC12 cell death induced by salsolinol and copper

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial participation in ischemic and traumatic neural cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antioxidant properties of zinc

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wilson's disease: a new gene and an animal model for an old disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Copper transport and its defect in Wilson disease: characterization of the copper-binding domain of Wilson disease ATPase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation spectrum of copper-induced DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor suppressor protein p53 mRNA and subcellular localization are altered by changes in cellular copper in human Hep G2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 inhibits p53 nuclear import following DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of copper with DNA and antagonism by other metals

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zinc-induced cortical neuronal death: contribution of energy failure attributable to loss of NAD(+) and inhibition of glycolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for p53-mediated modulation of neuronal viability.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12095159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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