(Q74415772)

English

Mechanisms involved in the establishment of tolerance through costimulatory blockade and BMT: lack of requirement for CD40L-mediated signaling for tolerance or deletion of donor-reactive CD4+ cells

scientific article published on 01 November 2001

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scholarly article

1 reference

Europe PubMed Central

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10 November 2019

Mechanisms involved in the establishment of tolerance through costimulatory blockade and BMT: lack of requirement for CD40L-mediated signaling for tolerance or deletion of donor-reactive CD4+ cells (English)

1 reference

Europe PubMed Central

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10 November 2019

3

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10 November 2019

author name string

J Kurtz

1

1 reference

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10 November 2019

H Ito

2

1 reference

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10 November 2019

J Shaffer

4

1 reference

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10 November 2019

M Sykes

5

1 reference

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10 November 2019

publication date

1 November 2001

1 reference

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10 November 2019

American Journal of Transplantation

1 reference

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10 November 2019

1

1 reference

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10 November 2019

4

1 reference

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10 November 2019

339-349

1 reference

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10 November 2019

Bone marrow chimerism and transplantation tolerance

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

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Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

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Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

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Cutting edge: administration of anti-CD40 ligand and donor bone marrow leads to hemopoietic chimerism and donor-specific tolerance without cytoreductive conditioning

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of the CD28 receptor during T cell responses to antigen

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Immune regulation by CD40 and its ligand GP39.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

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The CD40 pathway in allograft rejection, acceptance, and tolerance

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

CD40-CD40 ligand-independent activation of CD8+ T cells can trigger allograft rejection

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

CD4 T cell-mediated alloresistance to fully MHC-mismatched allogeneic bone marrow engraftment is dependent on CD40-CD40 ligand interactions, and lasting T cell tolerance is induced by bone marrow transplantation with initial blockade of this pathway

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Peripheral deletion after bone marrow transplantation with costimulatory blockade has features of both activation-induced cell death and passive cell death

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo administration of interleukin 2 plus T cell-depleted syngeneic marrow prevents graft-versus-host disease mortality and permits alloengraftment

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Additional monoclonal antibody (mAB) injections can replace thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mABs and 3-Gy whole body irradiation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Mls--a retrovirus exploits the immune system

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Genes encoding ligands for deletion of Vβ11 T cells cosegregate with mammary tumour virus genomes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

The MHC molecule I-E is necessary but not sufficient for the clonal deletion of V beta 11-bearing T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

The genetic basis of negative selection of Tcrb-V11+ T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Mice deficient for the CD40 ligand

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

CD40 ligand-transduced co-stimulation of T cells in the development of helper function

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

An essential role for gp39, the ligand for CD40, in thymic selection.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

CD4(+) T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Naive CD8+ T cells do not require costimulation for proliferation and differentiation into cytotoxic effector cells.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Prolonged acceptance of concordant and discordant xenografts with combined CD40 and CD28 pathway blockade

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Thymic dependence of loss of tolerance in mixed allogeneic bone marrow chimeras after depletion of donor antigen. Peripheral mechanisms do not contribute to maintenance of tolerance

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Intrathymic deletion of alloreactive T cells in mixed bone marrow chimeras prepared with a nonmyeloablative conditioning regimen

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-6143.2001.10409.X

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1034/J.1600-6143.2001.10409.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12099378%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12099378%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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