Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q74431200)
Watch
English
The problem, challenge and opportunity of genetic heterogeneity in monogenic diseases predisposing to sudden death
scientific article published on 01 July 2002
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12106944
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12106944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
editorial
0 references
review article
1 reference
stated in
Europe PubMed Central
title
The problem, challenge and opportunity of genetic heterogeneity in monogenic diseases predisposing to sudden death
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12106944
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12106944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
main subject
heterogeneity
1 reference
based on heuristic
inferred from title
author name string
Dan M Roden
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12106944
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12106944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
language of work or name
English
0 references
publication date
1 July 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12106944
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12106944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
published in
Journal of the American College of Cardiology
1 reference
stated in
Europe PubMed Central
PubMed ID
12106944
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12106944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
volume
40
1 reference
stated in
Europe PubMed Central
PubMed ID
12106944
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12106944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12106944
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12106944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
page(s)
357-359
1 reference
stated in
Europe PubMed Central
PubMed ID
12106944
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12106944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
cites work
Genotype-phenotype relationship in Brugada syndrome: electrocardiographic features differentiate SCN5A-related patients from non-SCN5A-related patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular and cellular mechanisms of cardiac arrhythmias
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low penetrance in the long-QT syndrome: clinical impact
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
KVLQT1 C-terminal missense mutation causes a forme fruste long-QT syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A common polymorphism associated with antibiotic-induced cardiac arrhythmia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The potential for QT prolongation and pro-arrhythmia by non-anti-arrhythmic drugs: clinical and regulatory implications. Report on a Policy Conference of the European Society of Cardiology.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased risk of arrhythmic events in long-QT syndrome with mutations in the pore region of the human ether-a-go-go-related gene potassium channel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of the genotype on the clinical course of the long-QT syndrome. International Long-QT Syndrome Registry Research Group.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade des pointes in LQT2 and LQT3 models of the long-QT syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ventricular fibrillation without apparent heart disease: description of six cases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Right bundle branch block, persistent ST segment elevation and sudden cardiac death: A distinct clinical and electrocardiographic syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
"Brugada" syndrome: clinical data and suggested pathophysiological mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic basis and molecular mechanism for idiopathic ventricular fibrillation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A single Na(+) channel mutation causing both long-QT and Brugada syndromes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical and molecular heterogeneity in the Brugada syndrome: a novel gene locus on chromosome 3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cardiac conduction defects associate with mutations in SCN5A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel arrhythmogenic mechanism revealed by a long-QT syndrome mutation in the cardiac Na(+) channel.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel mechanism for Brugada syndrome: defective surface localization of an SCN5A mutant (R1432G).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced Na(+) channel intermediate inactivation in Brugada syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flecainide-induced arrhythmia in canine ventricular epicardium. Phase 2 reentry?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Taking the "idio" out of "idiosyncratic": predicting torsades de pointes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Family history as a risk factor for primary cardiac arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Predicting sudden death in the population: the Paris Prospective Study I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differences in the electrophysiological response of canine ventricular epicardium and endocardium to ischemia. Role of the transient outward current
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sudden Cardiac Death, Genes, and Arrhythmogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0735-1097%2802%2901963-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0735-1097(02)01963-0
1 reference
stated in
Europe PubMed Central
PubMed ID
12106944
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12106944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
PubMed ID
12106944
1 reference
stated in
Europe PubMed Central
PubMed ID
12106944
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12106944%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit