(Q74476409)

English

A virus with a mutation in the ICP4-binding site in the L/ST promoter of herpes simplex virus type 1, but not a virus with a mutation in open reading frame P, exhibits cell-type-specific expression of gamma(1)34.5 transcripts and latency-associated

scientific article published on 01 May 1998

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scholarly article

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Europe PubMed Central

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11 November 2019

A virus with a mutation in the ICP4-binding site in the L/ST promoter of herpes simplex virus type 1, but not a virus with a mutation in open reading frame P, exhibits cell-type-specific expression of gamma(1)34.5 transcripts and latency-associated transcripts (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9557715%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

Herpes simplex virus type 1

1 reference

based on heuristic

inferred from title

author name string

L Y Lee

1

1 reference

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11 November 2019

P A Schaffer

2

1 reference

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11 November 2019

language of work or name

1 reference

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publication date

1 May 1998

1 reference

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11 November 2019

number of pages

15

1 reference

based on heuristic

inferred from page(s)

Journal of Virology

1 reference

Europe PubMed Central

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11 November 2019

72

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11 November 2019

5

1 reference

Europe PubMed Central

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11 November 2019

4250-4264

1 reference

Europe PubMed Central

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11 November 2019

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Method for induction of mutations in physically defined regions of the herpes simplex virus genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies to herpes simplex virus type 1 proteins, including the immediate-early protein ICP 4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of herpes simplex virus 1 alpha proteins 0, 4, and 27 with monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Herpes simplex virus type 1 ICP27 is an essential regulatory protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The terminal a sequence of the herpes simplex virus genome contains the promoter of a gene located in the repeat sequences of the L component.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification by antibody to a synthetic peptide of a protein specified by a diploid gene located in the terminal repeats of the L component of herpes simplex virus genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple phase-extraction assay for chloramphenicol acyltransferase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A variant of herpes simplex virus type 2 strain HG52 with a 1.5 kb deletion in RL between 0 to 0.02 and 0.81 to 0.83 map units is non-neurovirulent for mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Herpes simplex virus type 1 ICP0 plays a critical role in the de novo synthesis of infectious virus following transfection of viral DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The herpes simplex virus type 2 (HG52) variant JH2604 has a 1488 bp deletion which eliminates neurovirulence in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The herpes simplex virus 1 gene for ICP34.5, which maps in inverted repeats, is conserved in several limited-passage isolates but not in strain 17syn+.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ICP34.5 mutants of herpes simplex virus type 1 strain 17syn+ are attenuated for neurovirulence in mice and for replication in confluent primary mouse embryo cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the herpes simplex virus type 1 strain 17+ neurovirulence gene RL1 and its expression in a bacterial system

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The herpes simplex virus type 1 strain 17+ gamma 34.5 deletion mutant 1716 is avirulent in SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a herpes simplex virus 1 open reading frame antisense to the gamma(1)34.5 gene and transcribed by an RNA 3' coterminal with the unspliced latency-associated transcript.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell type and cell state determine differential in vitro growth of non-neurovirulent ICP34.5-negative herpes simplex virus types 1 and 2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of herpes simplex virus type 1 immediate-early gene expression by a cellular activity expressed in Vero and NB41A3 cells after growth arrest-release

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential response of human cells to deletions and stop codons in the gamma(1)34.5 gene of herpes simplex virus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication, establishment of latent infection, expression of the latency-associated transcripts and explant reactivation of herpes simplex virus type 1 gamma 34.5 mutants in a mouse eye model

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An avirulent ICP34.5 deletion mutant of herpes simplex virus type 1 is capable of in vivo spontaneous reactivation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-dose ocular infection with a herpes simplex virus type 1 ICP34.5 deletion mutant produces no corneal disease or neurovirulence yet results in wild-type levels of spontaneous reactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic properties of herpes simplex virus 1 containing a derepressed open reading frame P gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Open reading frame P--a herpes simplex virus gene repressed during productive infection encodes a protein that binds a splicing factor and reduces synthesis of viral proteins made from spliced mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of cis-acting sequences in the promoter of the herpes simplex virus type 1 latency-associated transcripts required for activation by nerve growth factor and sodium butyrate in PC12 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The product of ORF O located within the domain of herpes simplex virus 1 genome transcribed during latent infection binds to and inhibits in vitro binding of infected cell protein 4 to its cognate DNA site

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription of the derepressed open reading frame P of herpes simplex virus 1 precludes the expression of the antisense gamma(1)34.5 gene and may account for the attenuation of the mutant virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative sequence analysis of the long repeat regions and adjoining parts of the long unique regions in the genomes of herpes simplex viruses types 1 and 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Herpes simplex virus type 1 ICP0 regulates expression of immediate-early, early, and late genes in productively infected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral replication and latency reactivation kinetics of the non-neurovirulent herpes simplex virus type 1 variant 1716

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Status of the ICP34.5 gene in herpes simplex virus type 1 strain 17

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a promoter mapping within the reiterated sequences that flank the herpes simplex virus type 1 UL region.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication, establishment of latency, and induced reactivation of herpes simplex virus gamma 1 34.5 deletion mutants in rodent models

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel class of transcripts expressed with late kinetics in the absence of ICP4 spans the junction between the long and short segments of the herpes simplex virus type 1 genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collaborative complementation study of temperature-sensitive mutants of herpes simplex virus types 1 and 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/9557715

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.72.5.4250-4264.1998

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9557715%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9557715%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

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