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Nuclear aggregation of huntingtin is not prevented by deletion of chaperone Hsp104
scientific article published on 01 September 2001
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
title
Nuclear aggregation of huntingtin is not prevented by deletion of chaperone Hsp104
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
author
Jeremiah Levine
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
author name string
F Cao
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
S H Li
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
X J Li
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
language of work or name
English
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publication date
1 September 2001
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
published in
Biochimica et Biophysica Acta
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
volume
1537
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
page(s)
158-166
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
cites work
Glutamine repeats and neurodegenerative diseases: molecular aspects
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with expanded polyglutamine tract
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular chaperone functions of heat-shock proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic suppression of polyglutamine toxicity in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A huntingtin-associated protein enriched in brain with implications for pathology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular defects and altered gene expression in PC12 cells stably expressing mutant huntingtin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Support for the prion hypothesis for inheritance of a phenotypic trait in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0925-4439%2801%2900068-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0925-4439(01)00068-0
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
PubMed publication ID
11566259
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11566259
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11566259%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
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