(Q74549985)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9587957%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

Effect of GF120918, a potent P-glycoprotein inhibitor, on morphine pharmacokinetics and pharmacodynamics in the rat (English)

1 reference

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11 November 2019

1 reference

1 reference

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S P Letrent

1

1 reference

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11 November 2019

G M Pollack

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9587957%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

K R Brouwer

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9587957%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

K L Brouwer

series ordinal

4

1 reference

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11 November 2019

publication date

1 April 1998

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11 November 2019

published in

Pharmaceutical Research

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11 November 2019

volume

15

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11 November 2019

issue

4

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11 November 2019

page(s)

599-605

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MDR1 substrates/modulators protect against beta-estradiol-17beta-D-glucuronide cholestasis in rat liver

11 November 2019

cites work

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12 December 2020

In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative.

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12 December 2020

17 beta-estradiol glucuronide: an inducer of cholestasis and a physiological substrate for the multidrug resistance transporter

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12 December 2020

Fast reliable assay for morphine and its metabolites using high-performance liquid chromatography and native fluorescence detection

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12 December 2020

Microelectrometric titration measurement of the pKa's and partition and drug distribution coefficients of narcotics and narcotic antagonists and their pH and temperature dependence

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12 December 2020

Biliary excretion and enterohepatic recirculation of morphine-3-glucuronide in rats

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12 December 2020

Intrathecal morphine-3-glucuronide does not antagonize spinal antinociception by morphine or morphine-6-glucuronide in rats.

1 reference

12 December 2020

Evidence for P-glycoprotein-modulated penetration of morphine-6-glucuronide into brain capillary endothelium

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12 December 2020

The disposition of morphine and its 3- and 6-glucuronide metabolites in humans and animals, and the importance of the metabolites to the pharmacological effects of morphine.

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12 December 2020

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

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12 December 2020

Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine

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12 December 2020

P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

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12 December 2020

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12 December 2020

In vivo evidence for ATP-dependent and P-glycoprotein-mediated transport of cyclosporin A at the blood-brain barrier

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12 December 2020

Essential features of the P-glycoprotein pharmacophore as defined by a series of reserpine analogs that modulate multidrug resistance

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12 December 2020

Flow cytometric assay of modulation of P-glycoprotein function in whole blood by the multidrug resistance inhibitor GG918

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12 December 2020

Enterohepatic recirculation and renal metabolism of morphine in the rat

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12 December 2020

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

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12 December 2020

Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells.

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12 December 2020

Functional involvement of P-glycoprotein in blood-brain barrier

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12 December 2020

Effect of prior morphine-3-glucuronide exposure on morphine disposition and antinociception

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12 December 2020

Multidrug resistance in human cancer

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12 December 2020

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

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12 December 2020

Synthetic and natural opiates interact with P-glycoprotein in multidrug-resistant cells.

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12 December 2020

A simple, rapid method for the simultaneous determination of morphine and its principal metabolites in plasma using high-performance liquid chromatography and fluorometric detection

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12 December 2020

Lack of effect of morphine-3-glucuronide on the spinal antinociceptive actions of morphine in the rat: an electrophysiological study.

1 reference

12 December 2020

The effect of verapamil on the transport of peptides across the blood-brain barrier in rats: kinetic evidence for an apically polarized efflux mechanism

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1011938112599

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9587957%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

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