(Q74599393)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10074469%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

A hydrogen-bonding triad stabilizes the chemical transition state of a group I ribozyme (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10074469%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

author name string

Strobel SA

series ordinal

1

1 reference

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11 November 2019

Ortoleva-Donnelly L

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10074469%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

publication date

1 March 1999

1 reference

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11 November 2019

published in

Chemistry and Biology

1 reference

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11 November 2019

volume

6

1 reference

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11 November 2019

issue

3

1 reference

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11 November 2019

page(s)

153-165

1 reference

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Mechanistic aspects of enzymatic catalysis: lessons from comparison of RNA and protein enzymes

11 November 2019

cites work

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The chemistry of self-splicing RNA and RNA enzymes

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Group I intron self-splicing with adenosine: evidence for a single nucleoside-binding site

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7 January 2021

Sequence-specific endoribonuclease activity of the Tetrahymena ribozyme: enhanced cleavage of certain oligonucleotide substrates that form mismatched ribozyme-substrate complexes

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7 January 2021

Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site

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7 January 2021

Mechanistic investigations of a ribozyme derived from the Tetrahymena group I intron: insights into catalysis and the second step of self-splicing

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7 January 2021

Dynamics of ribozyme binding of substrate revealed by fluorescence-detected stopped-flow methods

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7 January 2021

Evidence for processivity and two-step binding of the RNA substrate from studies of J1/2 mutants of the Tetrahymena ribozyme

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7 January 2021

Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA.

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7 January 2021

Binding of guanosine and 3' splice site analogues to a group I ribozyme: interactions with functional groups of guanosine and with additional nucleotides

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7 January 2021

Effects of Mg2+ and the 2' OH of guanosine on steps required for substrate binding and reactivity with the Tetrahymena ribozyme reveal several local folding transitions

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7 January 2021

DNA cleavage catalysed by the ribozyme from Tetrahymena

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7 January 2021

The importance of being ribose at the cleavage site in the Tetrahymena ribozyme reaction

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7 January 2021

Contributions of 2'-hydroxyl groups of the RNA substrate to binding and catalysis by the Tetrahymena ribozyme. An energetic picture of an active site composed of RNA.

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7 January 2021

Dissection of the role of the conserved G.U pair in group I RNA self-splicing

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7 January 2021

Minor groove recognition of the conserved G.U pair at the Tetrahymena ribozyme reaction site

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7 January 2021

Exocyclic amine of the conserved G.U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5'-splice site selection and transition state stabilization

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7 January 2021

Quantitating tertiary binding energies of 2' OH groups on the P1 duplex of the Tetrahymena ribozyme: intrinsic binding energy in an RNA enzyme

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7 January 2021

Ribozymes: a distinct class of metalloenzymes

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7 January 2021

Metal ion requirements for sequence-specific endoribonuclease activity of the Tetrahymena ribozyme

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7 January 2021

Metal ion catalysis in the Tetrahymena ribozyme reaction

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7 January 2021

A second catalytic metal ion in group I ribozyme

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7 January 2021

Metal ion interaction with cosubstrate in self-splicing of group I introns

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7 January 2021

Ribozyme recognition of RNA by tertiary interactions with specific ribose 2′-OH groups

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7 January 2021

Comparison of binding of mixed ribose-deoxyribose analogues of CUCU to a ribozyme and to GGAGAA by equilibrium dialysis: evidence for ribozyme specific interactions with 2' OH groups

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7 January 2021

Tertiary interactions with the internal guide sequence mediate docking of the P1 helix into the catalytic core of the Tetrahymena ribozyme

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7 January 2021

Crystal structure of an RNA double helix incorporating a track of non-Watson-Crick base pairs

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7 January 2021

Complementary sets of noncanonical base pairs mediate RNA helix packing in the group I intron active site

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7 January 2021

Modification interference approach to detect ribose moieties important for the optimal activity of a ribozyme

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7 January 2021

DNA and RNA sequence determination based on phosphorothioate chemistry

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7 January 2021

Mutations in a nonconserved sequence of the Tetrahymena ribozyme increase activity and specificity

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7 January 2021

Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites

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7 January 2021

A minor groove RNA triple helix within the catalytic core of a group I intron

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7 January 2021

Translocation of an RNA duplex on a ribozyme

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7 January 2021

Identifying RNA minor groove tertiary contacts by nucleotide analogue interference mapping with N2-methylguanosine

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7 January 2021

Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom

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7 January 2021

A comparative database of group I intron structures

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7 January 2021

Crystal structure of a group I ribozyme domain: principles of RNA packing

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7 January 2021

Ribozyme inhibitors: deoxyguanosine and dideoxyguanosine are competitive inhibitors of self-splicing of the Tetrahymena ribosomal ribonucleic acid precursor

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7 January 2021

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7 January 2021

Direct demonstration of the catalytic role of binding interactions in an enzymatic reaction

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7 January 2021

Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

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7 January 2021

The 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction

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7 January 2021

Crystallographic studies of the catalytic mechanism of the neutral form of fructose-1,6-bisphosphatase

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7 January 2021

The chemical basis of adenosine conservation throughout the Tetrahymena ribozyme

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7 January 2021

A mutant T7 RNA polymerase as a DNA polymerase.

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7 January 2021

3'-end labeling of RNA with recombinant yeast poly(A) polymerase.

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7 January 2021

Miniribozymes, small derivatives of the sunY intron, are catalytically active

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7 January 2021

Replacement of the conserved G.U with a G-C pair at the cleavage site of the Tetrahymena ribozyme decreases binding, reactivity, and fidelity

1 reference

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7 January 2021

10.1016/S1074-5521(99)89007-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10074469%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference