(Q74623001)

English

Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium

scientific article published on 01 August 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12184536%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Balance between activation and inhibition of matrix metalloproteinase-2 (MMP-2) is altered in colorectal tumors compared to normal colonic epithelium (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12184536%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

author name string

Deborah L Ornstein

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12184536%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Kenneth H Cohn

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12184536%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

publication date

1 August 2002

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12184536%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Digestive Diseases and Sciences

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12184536%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

47

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12184536%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12184536%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1821-1830

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12184536%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

https://scigraph.springernature.com/pub.10.1023/a:1016456914723

0 references

Reversal of misfortune: TIMP-2 inhibits tumor cell invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinicopathologic significance of urokinase receptor- and MMP-9-positive stromal cells in human colorectal cancer: functional multiplicity of matrix degradation on hematogenous metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of antiangiogenic and antitumor efficacy of N-biphenyl sulfonyl-phenylalanine hydroxiamic acid (BPHA), an orally-active, selective matrix metalloproteinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marimastat (BB2516): current status of development

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imbalance of expression of matrix metalloproteinases (MMPs) and tissue inhibitors of the matrix metalloproteinases (TIMPs) in human pancreatic carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conversion of highly malignant colon cancer from an aggressive to a controlled disease by oral administration of a metalloproteinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of imbalance between MMP-2 and TIMP-2 in human neuroblastoma by reverse-transcription polymerase chain reaction and its correlation with tumor progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of colorectal cancer relapse and survival via tissue RNA levels of matrix metalloproteinase-9.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of tissue inhibitor of metalloproteinases TIMP-2 in human colorectal cancer--a predictor of tumour stage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metastatic and non-metastatic colorectal cancer (CRC) cells induce host metalloproteinase production in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent advances in matrix metalloproteinase inhibitors research.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Host expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in normal colon tissue affects metastatic potential of colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metastatic colorectal cancer cells induce matrix metalloproteinase release by human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MMP-1 is a prognostic marker for hematogenous metastasis of colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteases and protease inhibitors in tumor progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of fibroblast-derived matrix metalloproteinase-2 by colon-cancer cells in non-contact Co-cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase inhibition prevents colon cancer peritoneal carcinomatosis development and prolongs survival in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual over-expression pattern of membrane-type metalloproteinase-1 in cancer and stromal cells in human gastrointestinal carcinoma revealed by in situ hybridization and immunoelectron microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of matrix metalloproteinases and the tissue inhibitors of metalloproteinases and their local invasiveness and metastasis in Chinese human pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid generation of internal standards for competitive PCR by low-stringency primer annealing.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrilysin in early stage intestinal tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neoplastic progression of human colorectal cancer is associated with overexpression of the stromelysin-3 and BM-40/SPARC genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase inhibitors: applications in oncology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmented membrane type 1 matrix metalloproteinase (MT1-MMP):MMP-2 messenger RNA ratio in gastric carcinomas with poor prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic value of plasminogen activators and their inhibitors in colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated tissue inhibitor of metalloproteinase 1 RNA in colorectal cancer stroma correlates with lymph node and distant metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase-1 is associated with poor prognosis in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gelatinase A (MMP-2) and its mRNA detected in both neoplastic and stromal cells of tumors with different invasive and metastatic properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The significance of allelic deletions and aneuploidy in colorectal carcinoma. Results of a 5-year follow-up study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma membrane-bound tissue inhibitor of metalloproteinases (TIMP)-2 specifically inhibits matrix metalloproteinase 2 (gelatinase A) activated on the cell surface

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of matrix metalloproteinase-2 in human breast cancer cells overexpressing cyclooxygenase-1 or -2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression pattern of metalloproteinases and their inhibitors changes with the progression of human sporadic colorectal neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for tumor-host cooperation in regulating MMP-2 expression in human colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limited value of preoperative serum analyses of matrix metalloproteinases (MMP-2, MMP-9) and tissue inhibitors of matrix metalloproteinases (TIMP-1, TIMP-2) in colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane-type 1 matrix metalloproteinase mRNA expression in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced secretion and activation of matrilysin during malignant conversion of human colorectal epithelium and its relationship with invasive potential of colon cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12184536

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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