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Cyclooxygenases as the principal targets for the actions of NSAIDs
scientific article published on 01 August 1998
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Europe PubMed Central
PubMed publication ID
9710884
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9710884%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
review article
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Europe PubMed Central
title
Cyclooxygenases as the principal targets for the actions of NSAIDs
(English)
1 reference
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Europe PubMed Central
PubMed publication ID
9710884
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9710884%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
author
Terry J. Smith
series ordinal
1
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Europe PubMed Central
PubMed publication ID
9710884
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9710884%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
publication date
1 August 1998
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Europe PubMed Central
PubMed publication ID
9710884
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9710884%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
published in
Rheumatic Diseases Clinics of North America
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Europe PubMed Central
PubMed publication ID
9710884
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9710884%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
volume
24
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Europe PubMed Central
PubMed publication ID
9710884
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9710884%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
issue
3
1 reference
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Europe PubMed Central
PubMed publication ID
9710884
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9710884%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
page(s)
501-523
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Europe PubMed Central
PubMed publication ID
9710884
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9710884%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
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The mode of action of aspirin-like drugs: effect on inducible nitric oxide synthase
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Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis
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Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system
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7 January 2021
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L-745,337: a selective inhibitor of cyclooxygenase-2 elicits antinociception but not gastric ulceration in rats
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7 January 2021
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Prostaglandin E2 induces apoptosis in immature normal and malignant B lymphocytes
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Relative activities of retrovirally expressed murine prostaglandin synthase-1 and -2 depend on source of arachidonic acid
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Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase
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Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids.
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Involvement of nuclear factor kappa B in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes
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Crossref
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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
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Selective inhibition of cyclooxygenase-1 and -2 using intact insect cell assays
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Crossref
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7 January 2021
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Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II.
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7 January 2021
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15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
1 reference
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Crossref
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7 January 2021
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Toward an epidemiology of gastropathy associated with nonsteroidal antiinflammatory drug use.
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7 January 2021
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Nonsteroidal anti-inflammatory drug-associated gastropathy: incidence and risk factor models
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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
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CD40 expression by human fibroblasts
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7 January 2021
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Selective inhibition of NS-398 on prostanoid production in inflamed tissue in rat carrageenan-air-pouch inflammation
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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
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NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro
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Crossref
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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
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Human cyclooxygenase-2 cDNA
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7 January 2021
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Cytokine inter-relationships and their association with disease activity in arthritis
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7 January 2021
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Determination of cytokines in synovial fluids: correlation with diagnosis and histomorphological characteristics of synovial tissue
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Crossref
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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
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inferred from DOI database lookup
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
1 reference
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Crossref
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7 January 2021
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Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2
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7 January 2021
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Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect
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Crossref
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7 January 2021
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Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.
1 reference
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Crossref
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7 January 2021
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Nonsteroidal antiinflammatory drugs cause apoptosis and induce cyclooxygenases in chicken embryo fibroblasts
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
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Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme
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Crossref
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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
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Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic
1 reference
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Crossref
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7 January 2021
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Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
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Survival, prognosis, and causes of death in rheumatoid arthritis
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Crossref
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7 January 2021
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inferred from DOI database lookup
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.
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Crossref
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7 January 2021
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Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2.
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7 January 2021
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Tumorigenic transformation of immortalized ECV endothelial cells by cyclooxygenase-1 overexpression
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7 January 2021
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Alternate COX-2 Transcripts Are Differentially Regulated: Implications for Post-Transcriptional Control
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nonsteroidal anti-inflammatory drugs: practical and theoretical considerations in their selection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Self-promotion? Intimate connections between APC and prostaglandin H synthase-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prostaglandin-stimulated bone resorption by rheumatoid synovia. A possible mechanism for bone destruction in rheumatoid arthritis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pathogenesis of gastroduodenal injury due to nonsteroidal antiinflammatory drugs: implications for prevention and therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of eicosanoid biosynthesis by glucocorticoids in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human orbital fibroblasts are activated through CD40 to induce proinflammatory cytokine production.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of cyclooxygenase 1 and cyclooxygenase 2 in human synovial tissue: differential elevation of cyclooxygenase 2 in inflammatory joint diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs. A randomized, double-blind, placebo-controlled trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a phorbol ester-repressible v-src-inducible gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-Iiodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the genomic structure, chromosomal location and promoter of human prostaglandin H synthase-2 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Misoprostol for the treatment of peptic ulcer and antiinflammatory-drug-induced gastroduodenal ulceration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple second messenger pathways regulate IL-1 beta-induced expression of PGHS-2 mRNA in normal human skin fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of two Sp1 elements in basal endothelial prostaglandin H synthase-1 promoter activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional regulation of endothelial constitutive PGHS-1 expression by phorbol ester
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ligation of CD40 on fibroblasts induces CD54 (ICAM-1) and CD106 (VCAM-1) up-regulation and IL-6 production and proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-857X%2805%2970023-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0889-857X(05)70023-5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9710884
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9710884%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
PubMed publication ID
9710884
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9710884
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9710884%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
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