(Q77298424)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196191%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

title

Discriminatory residues in Ras and Rap for guanine nucleotide exchange factor recognition (English)

1 reference

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4 December 2019

2

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4 December 2019

author name string

N van den Berghe

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196191%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

A Wittinghofer

series ordinal

3

1 reference

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4 December 2019

language of work or name

English

0 references

publication date

1 April 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196191%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

4 December 2019

published in

1 reference

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4 December 2019

volume

274

1 reference

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4 December 2019

issue

16

1 reference

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4 December 2019

page(s)

11078-11085

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Kinetic analysis by fluorescence of the interaction between Ras and the catalytic domain of the guanine nucleotide exchange factor Cdc25Mm

4 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

The GTPase superfamily: a conserved switch for diverse cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

The GTPase superfamily: conserved structure and molecular mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Ras/Rap effector specificity determined by charge reversal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Ras‐effector interactions, the problem of specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Detection of genes with a potential for suppressing the transformed phenotype associated with activated ras genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Inhibition by cAMP of Ras-dependent activation of Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Cyclic AMP-dependent activation of Rap1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Rapid Ca2+-mediated activation of Rap1 in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL, and Grb2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Mitogenic and oncogenic properties of the small G protein Rap1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Dominant inhibitory Ras mutants selectively inhibit the activity of either cellular or oncogenic Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

The structural basis of the activation of Ras by Sos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

A rapid and efficient one-tube PCR-based mutagenesis technique using Pfu DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Analysis of intrinsic and CDC25-stimulated guanine nucleotide exchange of p21ras-nucleotide complexes by fluorescence measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Identification of a nucleotide exchange-promoting activity for p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Identification of residues of the H-ras protein critical for functional interaction with guanine nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Analysis of interaction between Ras and CDC25 guanine nucleotide exchange factor using yeast GAL4 two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Properties of the catalytic domain of sdc25p, a yeast GDP/GTP exchange factor of Ras proteins. Complexation with wild-type Ras2p, [S24N]Ras2p and [R80D, N81D]Ras2p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Residues crucial for Ras interaction with GDP-GTP exchangers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

The bovine papillomavirus E5 oncogene can cooperate with ras: identification of p21 amino acids critical for transformation by c-rasH but not v-rasH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Identification of amino acid residues required for Ras p21 target activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Heterogeneous Amino Acids in Ras and Rap1A Specifying Sensitivity to GAP Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Structural basis for the interaction of Ras with RalGDS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Differential structural requirements for interaction of Ras protein with its distinct downstream effectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Stimulation of gene induction and cell growth by the Ras effector Rlf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Amino-aromatic interactions in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Mutations at position 1122 in the catalytic domain of the mouse ras-specific guanine nucleotide exchange factor CDC25Mm originate both loss-of-function and gain-of-function proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.16.11078

21 January 2018

Identifiers

DOI

10.1074/JBC.274.16.11078

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10196191%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference