(Q77314513)

English

A simple assay system for examination of the inhibitory potential in vivo of decoy RNAs, ribozymes and other drugs by measuring the Tat-mediated transcription of a fusion gene composed of the long terminal repeat of HIV-1 and a gene for luciferase

scientific article published on 01 April 1998

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

A simple assay system for examination of the inhibitory potential in vivo of decoy RNAs, ribozymes and other drugs by measuring the Tat-mediated transcription of a fusion gene composed of the long terminal repeat of HIV-1 and a gene for luciferase (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

author name string

S Koseki

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

J Ohkawa

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

R Yamamoto

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

Y Takebe

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

K Taira

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

publication date

1 April 1998

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

Journal of Controlled Release

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

53

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1-3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

159-173

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

The structure, function and application of the hammerhead ribozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Self-splicing of group I introns

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Small catalytic RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A small catalytic oligoribonucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Simple RNA enzymes with new and highly specific endoribonuclease activities

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Metal ion catalysis in the Tetrahymena ribozyme reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

How many catalytic RNAs? Ions and the Cheshire cat conjecture.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Theoretical analyses on the role of Mg2+ ions in ribozyme reactions.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A general two-metal-ion mechanism for catalytic RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Ribozymes: a distinct class of metalloenzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Ionic interactions and the global conformations of the hammerhead ribozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Magnesium-mediated conversion of an inactive form of a hammerhead ribozyme to an active complex with its substrate. An investigation by NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Three-dimensional structure of a hammerhead ribozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Ribozymes: structure and mechanism in RNA catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Ribozymes that cleave an RNA sequence from human immunodeficiency virus: the effect of flanking sequence on rate

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Minimal sequence requirements for ribozyme activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Hammerhead ribozymes: importance of stem-loop II for activity

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Activity of hammerhead ribozymes containing non-nucleotidic linkers

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Kinetic characterization of intramolecular and intermolecular hammerhead RNAs with stem II deletions

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Dependence on Mg2+ ions of the activities of dimeric hammerhead minizymes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Catalytic activities of hammerhead ribozymes with a triterpenoid linker instead of stem/loop II

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of several kinds of dimer minizyme: simultaneous cleavage at two sites in HIV-1 tat mRNA by dimer minizymes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The hammerhead RNA domain, a model ribozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of divalent metal ions in the hammerhead RNA cleavage reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and Mg2+ binding

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Configurationally defined phosphorothioate-containing oligoribonucleotides in the study of the mechanism of cleavage of hammerhead ribozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Discrimination of a single base change in a ribozyme using the gene for dihydrofolate reductase as a selective marker in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Selection of the best target site for ribozyme-mediated cleavage within a fusion gene for adenovirus E1A-associated 300 kDa protein (p300) and luciferase.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Ribozymes as potential anti-HIV-1 therapeutic agents.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

RNA enzyme-directed gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Importance of independence in ribozyme reactions: kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Cellular transcription factors involved in the regulation of HIV-1 gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The trans-activator gene of the human T cell lymphotropic virus type III is required for replication

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

The trans-activator gene of HTLV-III is essential for virus replication

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

HIV-1 tat trans-activation requires the loop sequence within tar.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A discrete element 3' of human immunodeficiency virus 1 (HIV-1) and HIV-2 mRNA initiation sites mediates transcriptional activation by an HIV trans activator

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Tat trans-activates the human immunodeficiency virus through a nascent RNA target

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Elevated levels of mRNA can account for the trans-activation of human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcriptional but not translational regulation of HIV-1 by the tat gene product.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence-specific interaction of Tat protein and Tat peptides with the transactivation-responsive sequence element of human immunodeficiency virus type 1 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated trans-activation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Fragments of the HIV-1 Tat protein specifically bind TAR RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

RNA recognition by Tat-derived peptides: interaction in the major groove?

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

High affinity binding of TAR RNA by the human immunodeficiency virus type-1 tat protein requires base-pairs in the RNA stem and amino acid residues flanking the basic region

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of transcription by the TAR RNA of HIV-1 in a nuclear extract of HeLa cells

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Reporter genes: application to the study of mammalian gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat

1 reference

https://api.crossref.org/works/10.1016%2FS0168-3659%2897%2900250-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0168-3659(97)00250-2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9741924%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q77314513&oldid=1753166485"