(Q77315281)

English

A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein

scientific article published on 01 October 1998

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9742142%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9742142%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

author name string

N Ratner

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9742142%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

G S Bloom

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9742142%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

S T Brady

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9742142%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

publication date

1 October 1998

1 reference

Europe PubMed Central

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4 December 2019

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9742142%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

18

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9742142%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

19

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9742142%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

7717-7726

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9742142%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

Neurofibromatosis type 1 gene product (neurofibromin) associates with microtubules

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibromin is enriched in the endoplasmic reticulum of CNS neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the APC gene and their implications for protein structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APC gene: database of germline and somatic mutations in human tumors and cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of p34cdc2/cyclin B complex with microtubules in starfish oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mal3, the fission yeast homologue of the human APC-interacting protein EB-1 is required for microtubule integrity and the maintenance of cell form

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cyclin-dependent kinases by purine analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive overexpression of CDK2 inhibits neuronal differentiation of rat pheochromocytoma PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation-dependent inhibition by synapsin I of organelle movement in squid axoplasm.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel protein isoforms of the APC tumor suppressor in neural tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polarity orientation of axonal microtubules

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial motility in axons: membranous organelles may interact with the force generating system through multiple surface binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and functional diversity of microtubule motors in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The APC gene product associates with microtubules in vivo and promotes their assembly in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of beta-catenin and the adenomatous polyposis coli tumour suppressor protein in mouse neocortical cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P13suc1 associates with a cdc2-like kinase in a multimeric cytoskeletal complex in squid axoplasm

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple forms of the APC gene transcripts and their tissue-specific expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the tumor suppressor adenomatous polyposis coli (APC) by the cyclin-dependent kinase p34.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catalytic properties, tissue and intracellular distribution of neurofibromin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of the familial adenomatous polyposis coli gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic proteins and the assembly of synaptic junctions

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crosslinking of the surface immunoglobulin receptor in B lymphocytes induces a redistribution of neurofibromin but not p120-GAP

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the signaling activities of localization mutants of beta-catenin during axis specification in Xenopus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organelle transport along microtubules - the role of KIFs

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monomer-polymer equilibria in the axon: direct measurement of tubulin and actin as polymer and monomer in axoplasm

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A unique tubulin antibody which disrupts particle movement in squid axoplasm

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between wild type and mutant APC gene products.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APC binds to the novel protein EB1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Drosophila tumor suppressor gene dlg is required for normal synaptic bouton structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type but not mutant APC associates with the microtubule cytoskeleton.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the adenomatous polyposis coli protein and its possible regulatory effects in cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras signaling and NF1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microtubule-mediated transport of organelles and localization of beta-catenin to the future dorsal side of Xenopus eggs

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the APC gene product with beta-catenin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunochemical analysis of kinesin light chain function

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cdc2 phosphorylation is required for its interaction with cyclin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polarity of axoplasmic microtubules in the olfactory nerve of the frog

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of transcription factors and control of the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A kinesin medley: biochemical and functional heterogeneity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GTP gamma S inhibits organelle transport along axonal microtubules

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fast axonal transport in extruded axoplasm from squid giant axon

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A brain-specific activator of cyclin-dependent kinase 5.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cdc2-like kinase from rat spinal cord specifically phosphorylates KSPXK motifs in neurofilament proteins: isolation and characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure, function, and regulation of neuronal Cdc2-like protein kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the APC tumor suppressor protein with catenins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of full-length neurofibromin: tubulin inhibits Ras GAP activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microtubules and microtubule motors: mechanisms of regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of multiple protein kinases during the burst in protein phosphorylation that precedes the first meiotic cell division in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of the microtubule-binding and ATPase activities of kinesin by N-ethylmaleimide (NEM) suggests a role for sulfhydryls in fast axonal transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High levels of expression of the tumor suppressor gene APC during development of the rat central nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal cell cycles and their control

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tumor suppressor gene product APC is hyperphosphorylated during the M phase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to S phase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dimer formation by an N-terminal coiled coil in the APC protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of the APC gene product during neuronal differentiation of rat pheochromocytoma PC12 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The APC tumor suppressor protein in development and cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fast axonal transport in squid giant axon

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Video microscopy of fast axonal transport in extruded axoplasm: a new model for study of molecular mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular characterization of a neuronal-specific protein that stimulates the activity of Cdk5

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcellular localization of the APC protein: immunoelectron microscopic study of the association of the APC protein with catenin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attachment of transported vesicles to microtubules in axoplasm is facilitated by AMP-PNP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative splicing of the APC gene and its association with terminal differentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stable polymers of the axonal cytoskeleton: the axoplasmic ghost

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gelsolin inhibition of fast axonal transport indicates a requirement for actin microfilaments

1 reference

https://pubmed.ncbi.nlm.nih.gov/9742142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.18-19-07717.1998

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9742142%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9742142%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9742142%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

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