(Q77322580)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744576%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

title

Development of a comprehensive panel of antibodies against the major xenobiotic metabolising forms of cytochrome P450 in humans (English)

1 reference

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4 December 2019

5

1 reference

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4 December 2019

author name string

R J Edwards

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744576%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

D A Adams

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744576%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

P S Watts

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744576%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

D S Davies

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744576%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

language of work or name

English

0 references

publication date

1 August 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744576%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

published in

Biochemical Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744576%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

volume

56

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744576%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

issue

3

1 reference

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4 December 2019

page(s)

377-387

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744576%20AND%20SRC:MED&resulttype=core&format=json

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

4 December 2019

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Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer

7 January 2021

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Antibodies as probes of cytochrome P450 isozymes

7 January 2021

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Production and purification of antibodies against rat liver P450 enzymes

7 January 2021

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Use of monoclonal antibody probes against rat hepatic cytochromes P-450c and P-450d to detect immunochemically related isozymes in liver microsomes from different species

7 January 2021

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A monoclonal antibody raised to rat liver cytochrome P-448 (form C) which recognises an epitope common to many other forms of cytochrome P-450.

7 January 2021

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Cross-reactivity of thirteen monoclonal antibodies with ten vaccinia cDNA expressed rat, mouse and human cytochrome P450s

7 January 2021

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Inhibitory and non-inhibitory monoclonal antibodies to human cytochrome P450 3A3/4.

7 January 2021

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Inhibitory monoclonal antibodies to human cytochrome P450 2D6

7 January 2021

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22 Antipeptide antibodies in studies of cytochromes P450IA

7 January 2021

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An anti-peptide antibody targeted to a specific region of rat cytochrome P-450IA2 inhibits enzyme activity

7 January 2021

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Identification of a functionally conserved surface region of rat cytochromes P450IA

7 January 2021

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Antibodies to a synthetic peptide that react specifically with a common surface region on two hydrocarbon-inducible isoenzymes of cytochrome P-450 in the rat.

7 January 2021

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Facile SPS of peptides having C-terminal Asn and Gln.

7 January 2021

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Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens

7 January 2021

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Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human

7 January 2021

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An assay for paracetamol, produced by the O-deethylation of phenacetin in vitro, using gas chromatography/electron capture negative ion chemical ionization mass spectrometry

7 January 2021

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A simple and sensitive assay of 7-ethoxycoumarin deethylation

7 January 2021

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Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations

7 January 2021

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Assay of mephenytoin metabolism in human liver microsomes by high-performance liquid chromatography

7 January 2021

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Assay and characterisation of debrisoquine 4-hydroxylase activity of microsomal fractions of human liver

7 January 2021

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Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1

7 January 2021

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Solid-phase extraction of midazolam and two of its metabolites from plasma for high-performance liquid chromatographic analysis

7 January 2021

1 reference

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Cytochrome P-450 induction by clofibrate. Purification and properties of a hepatic cytochrome P-450 relatively specific for the 12- and 11-hydroxylation of dodecanoic acid (lauric acid)

7 January 2021

1 reference

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Short synthetic peptides exploited for reliable and specific targeting of antibodies to the C-termini of cytochrome P450 enzymes.

7 January 2021

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Distribution and induction of CYP3A1 and CYP3A2 in rat liver and extrahepatic tissues

7 January 2021

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Identification of CYP2E1 in marmoset monkey

7 January 2021

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Enoxacin is an inducer of CYP1A2 in rat liver

7 January 2021

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Biochemistry and molecular biology of the human CYP2C subfamily

7 January 2021

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Targeted antipeptide antibodies to cytochrome P450 2C18 based on epitope mapping of an inhibitory monoclonal antibody to P450 2C51

7 January 2021

1 reference

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Human hepatic CYP1A1 and CYP1A2 content, determined with specific anti-peptide antibodies, correlates with the mutagenic activation of PhIP.

7 January 2021

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Identification and location of alpha-helices in mammalian cytochromes P450

7 January 2021

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A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking

7 January 2021

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Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity

7 January 2021

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Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae

7 January 2021

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Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9

7 January 2021

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Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation

7 January 2021

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Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans

7 January 2021

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Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes

7 January 2021

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Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

7 January 2021

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Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat

7 January 2021

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Contribution of human CYP3A subfamily members to the 6-hydroxylation of chlorzoxazone

7 January 2021

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Specific inhibition of human CYP1A2 using a targeted antibody

7 January 2021

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Allelic and functional variability of cytochrome P4502C9.

7 January 2021

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Detection of CYP3A5 allelic variant: a candidate for the polymorphic expression of the protein?

7 January 2021

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Caffeine urinary metabolite ratios as markers of enzyme activity: a theoretical assessment.

7 January 2021

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Genetic Polymorphisms in the 5′-Flanking Region Change Transcriptional Regulation of the Human Cytochrome P450IIE1 Gene1

7 January 2021

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Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells

7 January 2021

1 reference

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Expression of CYP1A1 gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900033-1

Expression of xenobiotic-metabolizing cytochrome P450 forms in human full-term placenta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900033-1

Localization of CYP1A1 and CYP1A2 messenger RNA in normal human liver and in hepatocellular carcinoma by in situ hybridization

7 January 2021

1 reference

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Constitutive expression of hepatic cytochrome P450 genes

7 January 2021

1 reference

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Role of cytochrome P4501A2 in chemical carcinogenesis: implications for human variability in expression and enzyme activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900033-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(98)00033-1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9744576%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference