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Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme
scientific article published on 01 October 1998
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scholarly article
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stated in
Europe PubMed Central
PubMed publication ID
9748515
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
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4 December 2019
review article
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Europe PubMed Central
title
Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9748515
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
author name string
Y Pommier
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9748515
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
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4 December 2019
P Pourquier
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9748515
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
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4 December 2019
Y Fan
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9748515
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
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4 December 2019
D Strumberg
series ordinal
4
1 reference
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Europe PubMed Central
PubMed publication ID
9748515
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
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4 December 2019
language of work or name
English
0 references
publication date
1 October 1998
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9748515
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
published in
Biochimica et Biophysica Acta
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9748515
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
volume
1400
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9748515
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
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4 December 2019
issue
1-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9748515
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
page(s)
83-105
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9748515
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
cites work
DNA topoisomerases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Eukaryotic DNA topoisomerases I.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA topoisomerases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Recent studies of DNA topoisomerases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA topoisomerases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
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inferred from DOI database lookup
DNA topoisomerase poisons as antitumor drugs
1 reference
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Crossref
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7 January 2021
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A hyper-recombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase
1 reference
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7 January 2021
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Human TOP3: a single-copy gene encoding DNA topoisomerase III
1 reference
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7 January 2021
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Overexpression of a truncated human topoisomerase III partially corrects multiple aspects of the ataxia-telangiectasia phenotype
1 reference
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7 January 2021
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The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
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Mammalian DNA topoisomerase IIIalpha is essential in early embryogenesis
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
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Partial purification of .omega. protein from calf thymus
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
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inferred from DOI database lookup
ATP-dependent DNA topoisonmerase from D. melanogaster reversibly catenates duplex DNA rings
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of the mouse cDNA encoding DNA topoisomerase I and chromosomal location of the gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA Topoisomerase I from Mitochondria of Xenopus laevis Oocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
ATP inhibits nuclear and mitochondrial type I topoisomerases from human leukemia cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and characterization of a type I DNA topoisomerase from calf thymus mitochondria
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA topoisomerase I is essential in Drosophila melanogaster
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the mouse topoisomerase I gene by camptothecin selection
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Conditional growth of Escherichia coli caused by expression of vaccinia virus DNA topoisomerase I
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the topoisomerase I gene in serum stimulated human fibroblasts
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
A subthreshold level of DNA topoisomerases leads to the excision of yeast rDNA as extrachromosomal rings
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Using yeast to understand drugs that target topoisomerases.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential poisoning of human and Aspergillus nidulans DNA topoisomerase I by bi- and terbenzimidazoles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the aminocatechol A-3253 as an in vitro poison of DNA topoisomerase I from Candida albicans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
A DNA nicking-closing enzyme encapsidated in vaccinia virus: partial purification and properties
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a vaccinia virus gene encoding a type I DNA topoisomerase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and DNA sequence of the Shope fibroma virus DNA topoisomerase gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Partial transcriptional mapping of the fowlpox virus genome and analysis of the EcoRI L fragment
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genes of variola and vaccinia viruses necessary to overcome the host protective mechanisms
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
SFV Topoisomerase: Sequence Specificity in a Genetically Mapped Interval
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Topoisomerase I activity associated with human immunodeficiency virus (HIV) particles and equine infectious anemia virus core.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Topotecan inhibits human immunodeficiency virus type 1 infection through a topoisomerase-independent mechanism in a cell line with altered topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 reverse transcriptase: enhancement of activity by interaction with cellular topoisomerase I.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular topoisomerase I activity associated with HIV-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Topoisomerase I and II activities are required for Epstein-Barr virus replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of DNA topoisomerase I in the replication of herpes simplex virus type 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Knotted single-stranded DNA rings: a novel topological isomer of circular single-stranded DNA formed by treatment with Escherichia coli omega protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Breakage of single-stranded DNA by eukaryotic type 1 topoisomerase occurs only at regions with the potential for base-pairing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Eukaryotic DNA topoisomerase I reaction is topology dependent
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro preferential topoisomerization of bent DNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the function of eukaryotic DNA topoisomerase I: analysis of the binding step and of the catalytic constants of topoisomerization as a function of DNA topology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Eukaryotic topoisomerase I-DNA interaction is stabilized by helix curvature
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and characterization of human topoisomerase I mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping the active-site tyrosine of vaccinia virus DNA topoisomerase I.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Topoisomerase I interaction with SV40 DNA in the presence and absence of camptothecin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A model for the mechanism of human topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vaccinia DNA topoisomerase I: evidence supporting a free rotation mechanism for DNA supercoil relaxation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and mechanism of DNA topoisomerase II
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Site-specific ribonuclease activity of eukaryotic DNA topoisomerase I.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleosome positioning as a critical determinant for the DNA cleavage sites of mammalian DNA topoisomerase II in reconstituted simian virus 40 chromatin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA tridimensional context affects the reactivity of eukaryotic DNA topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of eukaryotic DNA topoisomerase I with nucleosomes and chromosomal proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential modulation by spermidine of reactions catalyzed by type 1 prokaryotic and eukaryotic topoisomerases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a camptothecin-resistant human DNA topoisomerase I in an in vitro system for Simian virus 40 DNA replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exposure to camptothecin breaks leading and lagging strand simian virus 40 DNA replication forks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of topoisomerase I and II cleavage sites on the Drosophila actin and Hsp70 heat shock genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Topoisomerase I interacts with transcribed regions in Drosophila cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Supercoiling of the DNA template during transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription and DNA supercoiling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA topoisomerase I is involved in both repression and activation of transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA recombinase activity of eukaryotic DNA topoisomerase I; effects of camptothecin and other inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of crossover points with topoisomerase I cleavage sites: a model for nonhomologous recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vaccinia DNA topoisomerase I promotes illegitimate recombination in Escherichia coli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resolution of Holliday junctions by eukaryotic DNA topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Camptothecin-induced in vivo topoisomerase I cleavages in the transcriptionally active tyrosine aminotransferase gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of specific topoisomerase I interactions within the transcribed region of active heat shock genes by using the inhibitor camptothecin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The anti-cancer drug camptothecin inhibits elongation but stimulates initiation of RNA polymerase II transcription.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microinjection of anti-topoisomerase I immunoglobulin G into nuclei of Chironomus tentans salivary gland cells leads to blockage of transcription elongation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Topoisomerase I enhances TFIID-TFIIA complex assembly during activation of transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel family of TRF (DNA topoisomerase I-related function) genes required for proper nuclear segregation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human DNA topoisomerase I-mediated cleavages stimulated by ultraviolet light-induced DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The promoter region of the human type-I-DNA-topoisomerase gene. Protein-binding sites and sequences involved in transcriptional regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural characterization of the human DNA topoisomerase I gene promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA topoisomerases from rat liver: physiological variations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the type I DNA topoisomerase gene in adenovirus-5 infected human cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene expression in regenerating liver in relation to cell proliferation and stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Virus- and cell-encoded tyrosine protein kinases inactivate DNA topoisomerases in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C phosphorylates DNA topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of purified Novikoff hepatoma topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of human topoisomerase I by protein kinase C in vitro and in phorbol 12-myristate 13-acetate-activated HL-60 promyelocytic leukaemia cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of DNA topoisomerase I is increased during the response of mammalian cells to mitogenic stimuli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A casein kinase type II (CKII)-like nuclear protein kinase associates with, phosphorylates, and activates topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Poly(ADP-ribosylation) of DNA Topoisomerase I: A Nuclear Response to DNA-strand Interruptions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutant cells defective in poly(ADP-ribose) synthesis due to stable alterations in enzyme activity or substrate availability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
(ADP-ribose)n participates in DNA excision repair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Poly(ADP-ribose) polymerase: a molecular nick-sensor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of DNA topoisomerase I and RNA polymerase I: a possible role for topoisomerase I in ribosomal gene transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of DNA Topoisomerase I Activity byp53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heat stress induces hsc70/nuclear topoisomerase I complex formation in vivo: evidence for hsc70-mediated, ATP-independent reactivation in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Simian virus 40 large T antigen binds to topoisomerase I.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between the N-terminus of human topoisomerase I and SV40 large T antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA topoisomerase-targeting antitumor drugs can be studied in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular resistance to camptothecins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The current status of camptothecin analogues as antitumor agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CPT-11 (Irinotecan) in the treatment of colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The clinical status of irinotecan (CPT-11), a novel water soluble camptothecin analogue: 1996.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Current perspectives on camptothecins in cancer treatment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential stabilization of eukaryotic DNA topoisomerase I cleavable complexes by camptothecin derivatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping in vivo topoisomerase I sites on simian virus 40 DNA: asymmetric distribution of sites on replicating molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific cleavage of chicken alpha A-globin and human c-Ha-ras genes by two molecular forms of calf thymus topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enrichment and depletion of Hela topoisomerase I recognition sites among specific types of DNA elements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
No alteration in DNA topoisomerase I gene related to CPT-11 resistance in human lung cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene mutation analysis and quantitation of DNA topoisomerase I in previously untreated non-small cell lung carcinomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SCT1 mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific interaction of camptothecin, a topoisomerase I inhibitor, with guanine residues of DNA detected by photoactivation at 365 nm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA topoisomerase II alpha is the major chromosome protein recognized by the mitotic phosphoprotein antibody MPM-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of topoisomerase I by anthracycline antibiotics: evidence for general inhibition of topoisomerase I by DNA-binding agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of mammalian DNA topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from fungus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
UCE6, a new antitumor antibiotic with topoisomerase I mediated DNA cleavage activity, from actinomycetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
UCE1022, a new antitumor antibiotic with topoisomerase I mediated DNA cleavage activity, from Paecilomyces
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Correlation between the formation of cleavable complex with topoisomerase I and growth-inhibitory activity for saintopin-type antibiotics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of DNA topoisomerase I isolated from the roots of Zanthoxylum nitidum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of topoisomerase I function by nitidine and fagaronine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and evaluation of new 6-amino- substituted benzo[c]phenanthridine derivatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Experimental antileukemic agents. Coralyne, analogs, and related compounds
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of topoisomerase I function by coralyne and 5,6-dihydrocoralyne
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of DNA topoisomerase I and II isolated from the Coptis rhizomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular Interactions of DNA-Topoisomerase I and II Inhibitor with DNA and Topoisomerases and in Ternary Complexes: Binding Modes and Biological Effects for Intoplicine Derivatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase I and pharmacology study of intoplicine (RP 60475; NSC 645008), novel topoisomerase I and II inhibitor, in cancer patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure-mutagenicity relationships in series of 11H-indolo[3,2-c]quinoline-1,4-diones, tetrahydro-11H-indolo[3,2-c]quinoline-1,4-diones and 11H-pyrido[3',4':4,5]pyrrolo[3,2-c]quinoline-1,4-diones with leukemia cytotoxic properties. Relations with
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differences in the topoisomerase I cleavage complexes formed by camptothecin and wakayin, a DNA-intercalating marine natural product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
UCT-4B, a new antitumor antibiotic with topoisomerase II mediated DNA cleavage activity, from streptomyces sp.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of mammalian DNA topoisomerase I mediated DNA cleavage by antitumor indolocarbazole derivatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antimetastatic effect of a novel indolocarbazole (NB-506) on IMC-HM murine tumor cells metastasized to the liver.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence-selective DNA cleavage by a topoisomerase I poison, NB-506.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of a Common Pathway of Apoptosis by Staurosporine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure-activity relationships in a series of substituted indolocarbazoles: topoisomerase I and protein kinase C inhibition and antitumoral and antimicrobial properties
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substituted 2,5'-Bi-1H-benzimidazoles: topoisomerase I inhibition and cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and evaluation of terbenzimidazoles as topoisomerase I inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA minor groove-binding ligands: a different class of mammalian DNA topoisomerase I inhibitors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure-activity relationships of benzimidazoles and related heterocycles as topoisomerase I poisons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stabilization of type I topoisomerase-DNA covalent complexes by actinomycin D
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antagonistic effect of aclarubicin on camptothecin induced cytotoxicity: role of topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of anthracenyl-amino acid conjugates as topoisomerase I and II inhibitors that circumvent drug resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle effects of the novel topoisomerase I inhibitor NU/ICRF 505 in a panel of Chinese hamster ovary cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular modeling of the interaction of anthracenyl-amino acid topoisomerase inhibitors with the DNA sequence d(CGTACG)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New naphthacenecarboxamide antibiotics, TAN-1518 A and B, have inhibitory activity against mammalian DNA topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distamycin inhibition of topoisomerase I-DNA interaction: a mechanistic analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of analogs of the DNA minor groove binder Hoechst 33258 on topoisomerase II and I mediated activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bisindolylmaleimides linked to DNA minor groove binding lexitropsins: synthesis, inhibitory activity against topoisomerase I, and biological evaluation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
beta-Lapachone, an inhibitor of oncornavirus reverse transcriptase and eukaryotic DNA polymerase-alpha. Inhibitory effect, thiol dependence and specificity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acylshikonin analogues: synthesis and inhibition of DNA topoisomerase-I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A strategy for identifying novel, mechanistically unique inhibitors of topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Naturally occurring inhibitors of topoisomerase I mediated DNA relaxation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TAN-1496 A, C and E, diketopiperazine antibiotics with inhibitory activity against mammalian DNA topoisomerase I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The dietary anticancer agent ellagic acid is a potent inhibitor of DNA topoisomerases in vitro.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of amino acids 361 to 364 of human topoisomerase I in camptothecin resistance and enzyme catalysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Detection of topoisomerase I gene point mutation in CPT-11 resistant lung cancer cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q12-13.2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900129-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0167-4781(98)00129-8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9748515
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
PubMed publication ID
9748515
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9748515
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748515%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
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