(Q77333829)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748618%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

review article

1 reference

title

Cellular resistance to topoisomerase-targeted drugs: from drug uptake to cell death (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748618%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference

A K Larsen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748618%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

A Skladanowski

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748618%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

language of work or name

English

0 references

publication date

1 October 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748618%20AND%20SRC:MED&resulttype=core&format=json

Biochimica et Biophysica Acta

4 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748618%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

volume

1400

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748618%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

issue

1-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748618%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

page(s)

257-274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748618%20AND%20SRC:MED&resulttype=core&format=json

Expression of a multidrug-resistance gene in human tumors and tissues

4 December 2019

cites work

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7 January 2021

Expression of a multidrug resistance gene in human cancers

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7 January 2021

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

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7 January 2021

The drug resistance-related protein LRP is the human major vault protein

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7 January 2021

Camptothecin sensitivity is mediated by the pleiotropic drug resistance network in yeast.

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7 January 2021

Cytotoxic activity of topotecan in human tumour cell lines and primary cultures of human tumour cells from patients

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7 January 2021

Early multidrug resistance, defined by changes in intracellular doxorubicin distribution, independent of P-glycoprotein

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7 January 2021

Defective pH regulation of acidic compartments in human breast cancer cells (MCF-7) is normalized in adriamycin-resistant cells (MCF-7adr).

1 reference

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7 January 2021

Redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin

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7 January 2021

The ATP-dependent glutathione S-conjugate export pump

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7 January 2021

Determinants of drug response in camptothecin-11-resistant glioma cell lines.

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7 January 2021

The transformation of irinotecan (CPT-11) to its active metabolite SN-38 by human liver microsomes. Differential hydrolysis for the lactone and carboxylate forms.

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7 January 2021

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7 January 2021

Nuclear DNA content and chromatin texture in multidrug-resistant human leukemic cell lines

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7 January 2021

Variation in topoisomerase I gene copy number as a mechanism for intrinsic drug sensitivity

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7 January 2021

Characterisation of a human small-cell lung cancer cell line resistant to the DNA topoisomerase I-directed drug topotecan

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7 January 2021

Sequential modifications of topoisomerase I activity in a camptothecin-resistant cell line established by progressive adaptation

1 reference

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7 January 2021

Nonproductive rearrangement of DNA topoisomerase I and II genes: correlation with resistance to topoisomerase inhibitors.

1 reference

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7 January 2021

The roles of DNA topoisomerase II during the cell cycle

1 reference

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7 January 2021

Effects of topoisomerase I inhibition on the expression of topoisomerase II alpha measured with fluorescence image cytometry

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7 January 2021

The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues

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7 January 2021

p53 regulates the minimal promoter of the human topoisomerase IIalpha gene

1 reference

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7 January 2021

Inhibition of DNA topoisomerase II alpha gene expression by the p53 tumor suppressor

1 reference

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7 January 2021

Glucose-regulated stresses induce resistance to camptothecin in human cancer cells

1 reference

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7 January 2021

Selection of a subpopulation with fewer DNA topoisomerase II alpha gene copies in a doxorubicin-resistant cell line panel

1 reference

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7 January 2021

Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II.

1 reference

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7 January 2021

Two COOH-terminal truncated cytoplasmic forms of topoisomerase II alpha in a VP-16-selected lung cancer cell line result from partial gene deletion and alternative splicing

1 reference

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7 January 2021

Formation of topoisomerase II alpha complexes with nascent DNA is related to VM-26-induced cytotoxicity

1 reference

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7 January 2021

Quantitative immunofluorescence and immunoelectron microscopy of the topoisomerase II alpha associated with nuclear matrices from wild-type and drug-resistant chinese hamster ovary cell lines

1 reference

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7 January 2021

Altered stability of etoposide-induced topoisomerase II-DNA complexes in resistant human leukaemia K562 cells

1 reference

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7 January 2021

A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons

1 reference

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7 January 2021

Involvement of amino acids 361 to 364 of human topoisomerase I in camptothecin resistance and enzyme catalysis

1 reference

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7 January 2021

Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites

1 reference

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7 January 2021

Detection of topoisomerase I gene point mutation in CPT-11 resistant lung cancer cell line

1 reference

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7 January 2021

Novel selection and genetic characterisation of an etoposide-resistant human leukaemic CCRF-CEM cell line

1 reference

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7 January 2021

A novel mutant topoisomerase II alpha present in VP-16-resistant human melanoma cell lines has a deletion of alanine 429.

1 reference

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7 January 2021

Expression of a mutant DNA topoisomerase II in CCRF-CEM human leukemic cells selected for resistance to teniposide

1 reference

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7 January 2021

Two independent amsacrine-resistant human myeloid leukemia cell lines share an identical point mutation in the 170 kDa form of human topoisomerase II

1 reference

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7 January 2021

Disruption of a topoisomerase-DNA cleavage complex by a DNA helicase

1 reference

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7 January 2021

Etoposide Sensitivity and Topoisomerase II Activity in Chinese Hamster V79 Monolayers and Small Spheroids

1 reference

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7 January 2021

Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity

1 reference

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7 January 2021

Cell-cycle-stage specificity of 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) and interaction with ionizing radiation in mammalian cell cultures

1 reference

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7 January 2021

Proliferation dependence of topoisomerase II mediated drug action

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7 January 2021

Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino) methanesulfon-m-anisidide and adriamycin

1 reference

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7 January 2021

Cell killing and DNA damage by etoposide in Chinese hamster V79 monolayers and spheroids: influence of growth kinetics, growth environment and DNA packaging

1 reference

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7 January 2021

Apurinic sites are position-specific topoisomerase II poisons.

1 reference

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7 January 2021

Position-specific effects of base mismatch on mammalian topoisomerase II DNA cleaving activity.

1 reference

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7 January 2021

Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I.

1 reference

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7 January 2021

Modulation of DNA Topoisomerase I Activity byp53

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900140-7

7 January 2021

Inhibition of cis-diamminedichloroplatinum (II)-induced DNA interstrand cross-link removal by 7-ethyl-10-hydroxy-camptothecin in HST-1 human squamous-carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900140-7

7 January 2021

Cytotoxic effects of topotecan combined with various anticancer agents in human cancer cell lines

1 reference

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7 January 2021

A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases

1 reference

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7 January 2021

Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae

1 reference

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7 January 2021

Induction of sister chromatid exchanges by inhibitors of topoisomerases

1 reference

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7 January 2021

Spontaneous DNA lesions poison human topoisomerase IIalpha and stimulate cleavage proximal to leukemic 11q23 chromosomal breakpoints

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900140-7

7 January 2021

11q23 aberration is an additional chromosomal change in de novo acute leukemia after treatment with etoposide and mitoxantrone

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900140-7

7 January 2021

EARLY EXPRESSION OF bcl-2 PROTEIN IN THE ADENOMA-CARCINOMA SEQUENCE OF COLORECTAL NEOPLASIA

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900140-7

7 January 2021

Bcl-2 protein expression in breast cancer in relation to established prognostic factors and other clinicopathological variables

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900140-7

7 January 2021

RNA polymerase signals UvrAB landing sites

1 reference

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7 January 2021

Elevated DNA topoisomerase II activity in nitrogen mustard-resistant human cells

1 reference

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7 January 2021

Effects of topoisomerase II inhibition in lymphoblasts from patients with progeroid and "chromosome instability" syndromes

1 reference

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7 January 2021

Restoration of X-ray and etoposide resistance, Ku-end binding activity and V(D) J recombination to the Chinese hamster sxi-3 mutant by a hamster Ku86 cDNA.

1 reference

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7 January 2021

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

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7 January 2021

Natural resistance of acute myeloid leukemia cell lines to mitoxantrone is associated with lack of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900140-7

7 January 2021

Expression of the mutated p53 tumor suppressor protein and its molecular and biochemical characterization in multidrug resistant MCF-7/Adr human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900140-7

7 January 2021

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

1 reference

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7 January 2021

Reducing the radiation-induced G2 delay causes HeLa cells to undergo apoptosis instead of mitotic death

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900140-7

7 January 2021

Spontaneous overexpression of the long form of the Bcl-X protein in a highly resistant P388 leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900140-7

7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900140-7

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2898%2900140-7

7 January 2021

10.1016/S0167-4781(98)00140-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9748618%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference