(Q77363798)

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Modulation of the toxic and mutagenic effects induced by methyl methanesulfonate in Chinese hamster ovary cells by overexpression of the rat N-alkylpurine-DNA glycosylase

scientific article published on 01 April 1999

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5 December 2019

Modulation of the toxic and mutagenic effects induced by methyl methanesulfonate in Chinese hamster ovary cells by overexpression of the rat N-alkylpurine-DNA glycosylase (English)

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5 December 2019

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F Calléja

1

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5 December 2019

J G Jansen

2

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5 December 2019

H Vrieling

3

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5 December 2019

F Laval

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5 December 2019

A A van Zeeland

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5 December 2019

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1 April 1999

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5 December 2019

Mutation Research

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5 December 2019

425

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5 December 2019

2

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5 December 2019

185-194

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5 December 2019

AT base pairs are the main target for mutations at the hprt locus of rat skin fibroblasts exposed in vitro to the monofunctional alkylating agent N-ethyl-N-nitrosourea

1 reference

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7 January 2021

Induction of hprt gene mutations in splenic T-lymphocytes from the rat exposed in vivo to DNA methylating agents is correlated with formation of O6-methylguanine in bone marrow and not in the spleen

1 reference

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7 January 2021

The relation between reaction kinetics and mutagenic action of mono-functional alkylating agents in higher eukaryotic systems. I. Recessive lethal mutations and translocations in Drosophila

1 reference

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7 January 2021

Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents

1 reference

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7 January 2021

Contribution of O6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: new insights gained from studies of genetically engineered mammalian cell lines

1 reference

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7 January 2021

DNA excision repair pathways

1 reference

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7 January 2021

Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase.

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7 January 2021

A chemical and genetic approach together define the biological consequences of 3-methyladenine lesions in the mammalian genome

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7 January 2021

Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate

1 reference

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7 January 2021

Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cells

1 reference

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7 January 2021

Increased resistance of the Chinese hamster mutant irs1 cells to monofunctional alkylating agents by transfection of the E. coli or mammalian N3-methyladenine-DNA-glycosylase genes

1 reference

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7 January 2021

Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents--a case of imbalanced DNA repair

1 reference

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7 January 2021

Increased removal of 3-alkyladenine reduces the frequencies of hprt mutations induced by methyl- and ethylmethanesulfonate in Chinese hamster fibroblast cells.

1 reference

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7 January 2021

3T3 NIH murine fibroblasts and B78 murine melanoma cells expressing the Escherichia coli N3-methyladenine-DNA glycosylase I do not become resistant to alkylating agents

1 reference

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7 January 2021

Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents

1 reference

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7 January 2021

Effect of nucleotide excision repair on hprt gene mutations in rodent cells exposed to DNA ethylating agents

1 reference

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7 January 2021

Methyl methanesulfonate-induced hprt mutation spectra in the Chinese hamster cell line CHO9 and its xrcc1-deficient derivative EM-C11.

1 reference

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7 January 2021

Strand-specific mutation spectra in repair-proficient and repair-deficient hamster cells.

1 reference

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7 January 2021

Insertion of nucleotides opposite apurinic/apyrimidinic sites in deoxyribonucleic acid during in vitro synthesis: uniqueness of adenine nucleotides

1 reference

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7 January 2021

Mutation frequency and spectrum resulting from a single abasic site in a single-stranded vector

1 reference

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7 January 2021

Expression of yeast but not human apurinic/apyrimidinic endonuclease renders Chinese hamster cells more resistant to DNA damaging agents

1 reference

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7 January 2021

The XRCC2 DNA repair gene: identification of a positional candidate

1 reference

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7 January 2021

Coding properties of a unique apurinic/apyrimidinic site replicated in mammalian cells

1 reference

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7 January 2021

An abasic site analogue activates a c-Ha-ras gene by a point mutation at modified and adjacent positions

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900034-2

7 January 2021

Impact of DNA nucleotide excision repair on methyl methanesulfonate-induced mutations in Drosophila melanogaster.

1 reference

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7 January 2021

Spectrum of mutations induced by methyl and ethyl methanesulfonate at the hprt locus of normal and tag expressing Chinese hamster fibroblasts

1 reference

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7 January 2021

In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome

1 reference

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7 January 2021

Site-specific mutagenesis by O6-alkylguanines located in the chromosomes of mammalian cells: influence of the mammalian O6-alkylguanine-DNA alkyltransferase

1 reference

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7 January 2021

DNA-mediated transfer and expression of a human DNA repair gene that demethylates O6-methylguanine

1 reference

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7 January 2021

Excision of 3-methylguanine from alkylated DNA by 3-methyladenine DNA glycosylase I of Escherichia coli

1 reference

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7 January 2021

Generation of a strong mutator phenotype in yeast by imbalanced base excision repair

1 reference

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7 January 2021

Release of normal bases from intact DNA by a native DNA repair enzyme

1 reference

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7 January 2021

Identifiers

10.1016/S0027-5107(99)00034-2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10216211%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10216211%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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