(Q77378696)

English

Treatment of resting zone chondrocytes with bone morphogenetic protein-2 induces maturation into a phenotype characteristic of growth zone chondrocytes by downregulating responsiveness to 24,25(OH)2D3 and upregulating responsiveness to 1,25-(OH)2D3

scientific article published on 01 December 1998

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10221593%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Treatment of resting zone chondrocytes with bone morphogenetic protein-2 induces maturation into a phenotype characteristic of growth zone chondrocytes by downregulating responsiveness to 24,25(OH)2D3 and upregulating responsiveness to 1,25-(OH)2D3 (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10221593%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10221593%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

author name string

Z Schwartz

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10221593%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

V L Sylvia

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10221593%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Y Liu

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10221593%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

B D Boyan

5

1 reference

Europe PubMed Central

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5 December 2019

publication date

1 December 1998

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10221593%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10221593%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10221593%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10221593%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

273-280

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10221593%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Inhibition of 1,25-(OH)2D3- and 24,25-(OH)2D3-dependent stimulation of alkaline phosphatase activity by A23187 suggests a role for calcium in the mechanism of vitamin D regulation of chondrocyte cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagenous bone matrix-induced endochondral ossification hemopoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of vitamin D metabolites on the plasma and matrix vesicle membranes of growth and resting cartilage cells in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of vitamin D3-responsive alkaline phosphatase in cultured chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic protein-2 inhibits the synthesis of insulin-like growth factor-binding protein-5 in bone cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone: formation by autoinduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of resting zone chondrocytes with transforming growth factor-beta 1 induces differentiation into a phenotype characteristic of growth zone chondrocytes by downregulating responsiveness to 24,25-(OH)2D3 and upregulating responsiveness to 1,

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of chondrogenesis in limb bud mesoderm cells by recombinant human bone morphogenetic protein 2B (BMP-2B) and modulation by transforming growth factor beta 1 and beta 2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of vitamin D metabolites on collagen production and cell proliferation of growth zone and resting zone cartilage cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth factors for bone growth and repair: IGF, TGF beta and BMP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human osteogenic protein 1 is a potent stimulator of the synthesis of cartilage proteoglycans and collagens by human articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic protein-induced cartilage development in tissue culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of phenotype by resting zone and growth region costochondral chondrocytes in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic protein-7 in growth-plate chondrocytes: regulation by retinoic acid is dependent on the stage of chondrocyte maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of transforming growth factor-beta on matrix synthesis by chick growth plate chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic proteins: background and implications for oral reconstruction. A review

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoblast responses to BMP-2-treated titanium in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of resting zone chondrocytes with 24,25-dihydroxyvitamin D3 [24,25-(OH)2D3] induces differentiation into a 1,25-(OH)2D3-responsive phenotype characteristic of growth zone chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nongenomic regulation of chondrocyte membrane fluidity by 1,25-(OH)2D3 and 24,25-(OH)2D3 is dependent on cell maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Collagenase-3 (MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells, and osteoblasts during human fetal bone development

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dexamethasone promotes von kossa-positive nodule formation and increased alkaline phosphatase activity in costochondral chondrocyte cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic protein signaling is required for maintenance of differentiated phenotype, control of proliferation, and hypertrophy in chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 by growth zone and resting zone chondrocytes is dependent on cell maturation and is regulated by hormones and growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nongenomic regulation of protein kinase C isoforms by the vitamin D metabolites 1 alpha,25-(OH)2D3 and 24R,25-(OH)2D3

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of 1,25(OH)2D3 and 24,25(OH)2D3 on calcium ion fluxes in costochondral chondrocyte cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1,25-Dihydroxyvitamin D3 and human bone-derived cells in vitro: effects on alkaline phosphatase, type I collagen and proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid chondrocyte maturation by serum-free culture with BMP-2 and ascorbic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial cell lines that induce bone formation in vivo produce alkaline phosphatase-enriched matrix vesicles in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current concepts of the physiology and biochemistry of calcification

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of vitamin D metabolites on the expression of alkaline phosphatase activity by epiphyseal hypertrophic chondrocytes in primary cell culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Responsiveness of clonal limb bud cell lines to bone morphogenetic protein 2 reveals a sequential relationship between cartilage and bone cell phenotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D metabolites regulate matrix vesicle metalloproteinase content in a cell maturation-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synergistic effect of TGF beta and 24,25-(OH)2D3 on resting zone chondrocytes is metabolite-specific and mediated by PKC

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of protein kinase C by transforming growth factor beta 1 in rat costochondral chondrocyte cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic protein 2 stimulates articular cartilage proteoglycan synthesis in vivo but does not counteract interleukin-1alpha effects on proteoglycan synthesis and content

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta modulates the expression of osteoblast and chondroblast phenotypes in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial effects of partially purified bone morphogenetic protein on the expression of glycosaminoglycan, collagen, and alkaline phosphatase in nonunion cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant bone morphogenetic protein (BMP)-2 regulates costochondral growth plate chondrocytes and induces expression of BMP-2 and BMP-4 in a cell maturation-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of prostaglandin E2 production by vitamin D metabolites in growth zone and resting zone chondrocyte cultures is dependent on cell maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maturation-dependent regulation of protein kinase C activity by vitamin D3 metabolites in chondrocyte cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C and lipid signaling for sustained cellular responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant transforming growth factor-beta1 induces endochondral bone in the baboon and synergizes with recombinant osteogenic protein-1 (bone morphogenetic protein-7) to initiate rapid bone formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of vitamin D metabolites on phospholipase A2 activity of growth zone and resting zone cartilage cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of immortalized cells derived from 13DPC mouse limb buds as a system to study the effects of recombinant human bone morphogenetic protein-2 (rhBMP-2) on limb bud cell differentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct effects of 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 on growth zone and resting zone chondrocyte membrane alkaline phosphatase and phospholipase-A2 specific activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dependence of mesenchymal cell responses on duration of exposure to bone morphogenetic protein-2 in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10221593

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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