(Q77425114)

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Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3

scientific article published on 01 October 1998

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5 December 2019

Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3 (English)

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5 December 2019

Kiyoshi Itagaki

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D H Lang

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C K Yeung

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R M Peter

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C Ibarra

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R Gasser

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R M Philpot

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A E Rettie

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1 October 1998

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Biochemical Pharmacology

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1005-1012

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5 December 2019

The fish-odor syndrome

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The metabolism of 14C-labelled trimethylamine and its N-oxide in man

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Recent studies on the structure and function of multisubstrate flavin-containing monooxygenases

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A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities

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Differential developmental and tissue-specific regulation of expression of the genes encoding three members of the flavin-containing monooxygenase family of man, FMO1, FMO3 and FM04

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Characterization of flavin-containing monooxygenase 5 (FMO5) cloned from human and guinea pig: evidence that the unique catalytic properties of FMO5 are not confined to the rabbit ortholog

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Disclosure of the metabolic retroversion of trimethylamine N-oxide in humans: a pharmacogenetic approach

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Urinary excretion of trimethylamine and trimethylamine oxide following trimethylamine-administration to normals and to patients with liver disease

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Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome

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Identification of enzymes involved in the metabolism of atrazine, terbuthylazine, ametryne, and terbutryne in human liver microsomes

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Expression and characterization of a modified flavin-containing monooxygenase 4 from humans

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Human flavin-containing monooxygenase form 3: cDNA expression of the enzymes containing amino acid substitutions observed in individuals with trimethylaminuria.

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Multisubstrate flavin-containing monooxygenases: applications of mechanism to specificity

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Expression in Escherichia coli of the flavin-containing monooxygenase D (form II) from adult human liver: determination of a distinct tertiary amine substrate specificity

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7 January 2021

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10.1016/S0006-2952(98)00218-4

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5 December 2019

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