(Q77448607)

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Induction of UDP-glycosyltransferase family 1 genes in rat liver: different patterns of mRNA expression with two inducers, 3-methylcholanthrene and beta-naphthoflavone

scientific article published on 01 September 1998

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5 December 2019

Induction of UDP-glycosyltransferase family 1 genes in rat liver: different patterns of mRNA expression with two inducers, 3-methylcholanthrene and beta-naphthoflavone (English)

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5 December 2019

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S T Saarikoski

1

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5 December 2019

T S Ikonen

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5 December 2019

T Oinonen

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5 December 2019

K O Lindros

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5 December 2019

I Ulmanen

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5 December 2019

K Husgafvel-Pursiainen

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5 December 2019

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1 September 1998

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5 December 2019

Biochemical Pharmacology

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5 December 2019

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5 December 2019

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5 December 2019

569-575

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5 December 2019

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

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Drug glucuronidation in humans

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Drug-Responsive and Tissue-Specific Alternative Expression of Multiple First Exons in Rat UDP-Glucuronosyltransferase Family 1 (UGT1) Gene Complex

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Formation of mono- and diglucuronides and other glycosides of benzo(a)pyrene-3,6-quinol by V79 cell-expressed human phenol UDP-glucuronosyltransferases of the UGT1 gene complex

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Tissue-specific constitutive and inducible expression of rat phenol UDP-glucuronosyltransferase

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Tissue-specific 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible expression of human UDP-glucuronosyltransferase UGT1A6.

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Drug-metabolizing enzymes in ligand-modulated transcription

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Zonation of cytochrome P450 expression, drug metabolism and toxicity in liver

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Effect of different doses of 3-methylcholanthrene on the localization of the 3-methylcholanthrene-inducible isoenzymes of cytochrome P450 within the centrilobular and periportal zones of the rat liver

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7 January 2021

Dose-dependent acinar induction of cytochromes P450 in rat liver. Evidence for a differential mechanism of induction of P450IA1 by β-naphthoflavone and dioxin

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Characterization, localization and regulation of a novel phenobarbital-inducible form of cytochrome P450, compared with three further P450-isoenzymes, NADPH P450-reductase, glutathione transferases and microsomal epoxide hydrolase.

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7 January 2021

Pretranslational induction of cytochrome P4501A enzymes by beta-naphthoflavone and 3-methylcholanthrene occurs in different liver zones

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Aryl hydrocarbon receptor-associated genes in rat liver: regional coinduction of aldehyde dehydrogenase 3 and glutathione transferase Ya

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Structure of the rat catechol-O-methyltransferase gene: separate promoters are used to produce mRNAs for soluble and membrane-bound forms of the enzyme

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Localization of CYP1A1 mRNA in human lung by in situ hybridization: comparison with immunohistochemical findings

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7 January 2021

Xenobiotic responsive element-mediated transcriptional activation in the UDP-glucuronosyltransferase family 1 gene complex

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Induction of a rat liver benzo[a]pyrene-trans-7,8-dihydrodiol glucuronidating activity by oltipraz and beta-naphthoflavone

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Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

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Identification and analysis of drug-responsive expression of UDP-glucuronosyltransferase family 1 (UGT1) isozyme in rat hepatic microsomes using anti-peptide antibodies

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A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus

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Intralobular distribution of UDP-glucuronosyltransferase in livers from untreated, 3-methylcholanthrene- and phenobarbital-treated rats

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Hepatic zonation of drug metabolizing enzymes. Studies on hepatocytes isolated from the periportal or perivenous region of the liver acinus.

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Heterogeneous expression of UDP-glucuronosyltransferases in periportal and perivenous hepatocytes.

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Expression and role of the human liver UDP-glucuronosyltransferase UGT1*6 analyzed by specific antibodies raised against a hybrid protein produced in Escherichia coli.

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Lobular distribution of human liver phenol and bilirubin uridine 5'-diphosphate glucuronosyltransferase messenger RNAs

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Identifiers

10.1016/S0006-2952(97)00662-X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9783725%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9783725%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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