(Q77545285)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9813066%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

title

Intragenic suppressors of mutant DNA topoisomerase I-induced lethality diminish enzyme binding of DNA (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9813066%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

author name string

C L Hann

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9813066%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

A L Carlberg

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9813066%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

M A Bjornsti

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9813066%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

language of work or name

English

0 references

publication date

1 November 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9813066%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

6 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9813066%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

volume

273

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9813066%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

issue

47

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9813066%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

page(s)

31519-31527

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9813066%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Topoisomerase poisons: harnessing the dark side of enzyme mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

DNA topoisomerases: essential enzymes and lethal targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Eukaryotic DNA topoisomerases I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Cloning of yeast TOP1, the gene encoding DNA topoisomerase I, and construction of mutants defective in both DNA topoisomerase I and DNA topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

A novel family of TRF (DNA topoisomerase I-related function) genes required for proper nuclear segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

DNA topoisomerase-targeting antitumor drugs can be studied in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Alterations in the catalytic activity of yeast DNA topoisomerase I result in cell cycle arrest and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

A 26 kDa yeast DNA topoisomerase I fragment: crystallographic structure and mechanistic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Reconstitution of human topoisomerase I by fragment complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

A model for the mechanism of human topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Proteolytic footprinting of vaccinia topoisomerase bound to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Detection of topoisomerase I gene point mutation in CPT-11 resistant lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

SCT1 mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Increased camptothecin toxicity induced in mammalian cells expressing Saccharomyces cerevisiae DNA topoisomerase I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Recovery of plasmids from yeast into Escherichia coli: shuttle vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Camptothecin sensitivity is mediated by the pleiotropic drug resistance network in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Expression of yeast DNA topoisomerase I can complement a conditional-lethal DNA topoisomerase I mutation in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Intragenic suppressors of P-loop mutations in the beta-subunit of the mitochondrial ATPase in the yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Genetic interactions among the transmembrane segments of the G protein coupled receptor encoded by the yeast STE2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Supercoiling of intracellular DNA can occur in eukaryotic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Mutational analysis of vaccinia virus topoisomerase identifies residues involved in DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Crystal structure of the amino-terminal fragment of vaccinia virus DNA topoisomerase I at 1.6 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Mutational analysis of 26 residues of vaccinia DNA topoisomerase identifies Ser-204 as important for DNA binding and cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

Involvement of amino acids 361 to 364 of human topoisomerase I in camptothecin resistance and enzyme catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.47.31519

21 January 2018

Identifiers

DOI

10.1074/JBC.273.47.31519

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9813066%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference