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Src homology-2 domains: structure, mechanisms, and drug discovery
scientific article published on 01 January 1998
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9817027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9817027%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Src homology-2 domains: structure, mechanisms, and drug discovery
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9817027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9817027%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
main subject
drug discovery
1 reference
based on heuristic
inferred from title
author name string
Sawyer TK
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9817027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9817027%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
publication date
1 January 1998
1 reference
stated in
Europe PubMed Central
PubMed ID
9817027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9817027%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
published in
Biopolymers
1 reference
stated in
Europe PubMed Central
PubMed ID
9817027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9817027%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
volume
47
1 reference
stated in
Europe PubMed Central
PubMed ID
9817027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9817027%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
page(s)
243-261
1 reference
stated in
Europe PubMed Central
PubMed ID
9817027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9817027%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed ID
9817027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9817027%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
cites work
Protein kinase inhibitors: the tyrosine-specific protein kinases
1 reference
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Crossref
reference URL
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21 January 2018
Protein tyrosine phosphatases in signal transduction.
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21 January 2018
New intracellular targets for therapeutic drug design
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21 January 2018
SH2 domains recognize specific phosphopeptide sequences
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reference URL
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21 January 2018
Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav
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21 January 2018
Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides
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21 January 2018
Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms
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21 January 2018
Design, synthesis, and cocrystal structure of a nonpeptide Src SH2 domain ligand
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reference URL
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21 January 2018
Three-dimensional solution structure of the src homology 2 domain of c-abl
1 reference
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reference URL
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21 January 2018
Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode
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21 January 2018
Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase
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21 January 2018
Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide
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21 January 2018
Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck
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21 January 2018
Solution structure of the C-terminal SH2 domain of the human tyrosine kinase Syk complexed with a phosphotyrosine pentapeptide
1 reference
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21 January 2018
Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor
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21 January 2018
Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides
1 reference
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Crossref
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21 January 2018
Potent activation of phosphatidylinositol 3'-kinase by simple phosphotyrosine peptides derived from insulin receptor substrate 1 containing two YMXM motifs for binding SH2 domains
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21 January 2018
Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1
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21 January 2018
Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor
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21 January 2018
Direct determination of the sequence recognition requirements of the SH2 domains of SH-PTP2
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21 January 2018
F2(Pmp)2-TAM zeta 3, a novel competitive inhibitor of the binding of ZAP-70 to the T cell antigen receptor, blocks early T cell signaling
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21 January 2018
Cellular functions regulated by Src family kinases
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21 January 2018
L-O-(2-malonyl)tyrosine: a new phosphotyrosyl mimetic for the preparation of Src homology 2 domain inhibitory peptides
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21 January 2018
Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study
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21 January 2018
Design of peptidomimetic ligands for the pp60src SH2 domain
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21 January 2018
The Role of 4-phosphonodifluoromethyl- and 4-phosphono-phenylalanine in the selectivity and cellular uptake of SH2 domain ligands
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21 January 2018
Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors.
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21 January 2018
Potent inhibition of insulin receptor dephosphorylation by a hexamer peptide containing the phosphotyrosyl mimetic F2Pmp
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21 January 2018
Discovery of 3-aminobenzyloxycarbonyl as an N-terminal group conferring high affinity to the minimal phosphopeptide sequence recognized by the Grb2-SH2 domain
1 reference
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21 January 2018
Structure-based design and synthesis of high affinity tripeptide ligands of the Grb2-SH2 domain
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21 January 2018
Solid phase synthesis of a biased mini tetrapeptoid-library for the discovery of monodentate ITAM mimics as ZAP-70 inhibitors
1 reference
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retrieved
21 January 2018
Identifiers
DOI
10.1002/(SICI)1097-0282(1998)47:3<243::AID-BIP4>3.0.CO;2-P
0 references
PubMed ID
9817027
1 reference
stated in
Europe PubMed Central
PubMed ID
9817027
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9817027%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
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