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The proteasome inhibitor lactacystin prevents the generation of an endoplasmic reticulum leader-derived T cell epitope
scientific article published on 01 July 1998
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
title
The proteasome inhibitor lactacystin prevents the generation of an endoplasmic reticulum leader-derived T cell epitope
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
main subject
endoplasmic reticulum
1 reference
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inferred from title
author
Awen Gallimore
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
author name string
K Schwarz
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
M van den Broek
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
H Hengartner
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
M Groettrup
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
publication date
1 July 1998
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
published in
Molecular Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
volume
35
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
issue
10
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
page(s)
581-591
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
cites work
The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
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Identification of a Tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
Lymphocytic choriomeningitis virus. VI. Isolation of a glycoprotein mediating neutralization
1 reference
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Crossref
reference URL
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7 January 2021
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Immunodominant T cell epitope from signal sequence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2898%2900053-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2898%2900053-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2898%2900053-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanistic studies on the inactivation of the proteasome by lactacystin: a central role for clasto-lactacystin beta-lactone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2898%2900053-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2898%2900053-4
retrieved
7 January 2021
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A novel chymotrypsin-like component of the multicatalytic proteinase complex optimally active at acidic pH
1 reference
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Crossref
reference URL
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7 January 2021
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A viral inhibitor of peptide transporters for antigen presentation
1 reference
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Crossref
reference URL
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Proteasomes play an essential role in thymocyte apoptosis
1 reference
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7 January 2021
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A third interferon-gamma-induced subunit exchange in the 20S proteasome.
1 reference
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Crossref
reference URL
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7 January 2021
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Peptide antigen production by the proteasome: complexity provides efficiency
1 reference
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Crossref
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7 January 2021
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HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation
1 reference
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Crossref
reference URL
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7 January 2021
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Herpes simplex virus turns off the TAP to evade host immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2898%2900053-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0161-5890%2898%2900053-4
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7 January 2021
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Strictly transporter of antigen presentation (TAP)-dependent presentation of an immunodominant cytotoxic T lymphocyte epitope in the signal sequence of a virus protein
1 reference
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Crossref
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The signal sequence of lymphocytic choriomeningitis virus contains an immunodominant cytotoxic T cell epitope that is restricted by both H-2D(b) and H-2K(b) molecules
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The protease inhibitor, N-acetyl-L-leucyl-L-leucyl-leucyl-L-norleucinal, decreases the pool of major histocompatibility complex class I-binding peptides and inhibits peptide trimming in the endoplasmic reticulum
1 reference
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Crossref
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7 January 2021
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The alpha chain of the T cell antigen receptor is degraded in the cytosol
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1016%2FS0161-5890%2898%2900053-4
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7 January 2021
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Signal sequence processing in rough microsomes
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Signal peptide fragments of preprolactin and HIV-1 p-gp160 interact with calmodulin
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Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme
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Crossref
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Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter
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Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons.
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Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
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Two novel routes of transporter associated with antigen processing (TAP)-independent major histocompatibility complex class I antigen processing
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Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter
1 reference
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TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells
1 reference
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Crossref
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HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides
1 reference
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Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction
1 reference
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Crossref
reference URL
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Cytosolic degradation of T-cell receptor alpha chains by the proteasome
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0161-5890(98)00053-4
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
PubMed ID
9823757
1 reference
stated in
Europe PubMed Central
PubMed ID
9823757
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9823757%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
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