(Q77586745)

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Oxidation of defined antigens allows protein unfolding and increases both proteolytic processing and exposes peptide epitopes which are recognized by specific T cells

scientific article published on 01 November 1998

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9824492%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

Oxidation of defined antigens allows protein unfolding and increases both proteolytic processing and exposes peptide epitopes which are recognized by specific T cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9824492%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

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Carmen Alvarez-Dominguez

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9824492%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

author name string

E Carrasco-Marín

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9824492%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

J E Paz-Miguel

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9824492%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

P López-Mato

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9824492%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

F Leyva-Cobián

5

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Europe PubMed Central

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6 December 2019

publication date

1 November 1998

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9824492%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9824492%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

95

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9824492%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9824492%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

314-321

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9824492%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

Selective inhibition of the inducible nitric oxide synthase by aminoguanidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of superoxide by phagocytic leukocytes: a paradigm for stimulus-response phenomena.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wortmannin, an inhibitor of phospholipase D activation, selectively blocks major histocompatibility complex class II-restricted antigen presentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron salts and iron-containing porphyrins block presentation of protein antigens by macrophages to MHC class II-restricted T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Destruction of proteins as a creative force

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of mouse invariant chain: roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil chloramines: missing links between innate and acquired immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosomal heterogeneity between and within cells with respect to resistance against oxidative stress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fractionation of oxidized insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of rotenone in vitro by tissue homogenates from mammals and insects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective Free Radical Reactions with Proteins and Enzymes: The Inactivation of Ribonuclease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic and functonal studies on activated mouse macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative Peptide Cleavage and Decarboxylation by the MPO-H 2 O 2 -Cl − Antimicrobial System

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in Oxygen Metabolism of Phagocytosing Monocytes and Neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bactericidal activity of a superoxide anion-generating system. A model for the polymorphonuclear leukocyte

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible involvement of proteases in superoxide production by human polymorphonuclear leukocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease inhibitors antagonize the activation of polymorphonuclear leukocyte oxygen consumption

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological reactivity of hypochlorous acid: implications for microbicidal mechanisms of leukocyte myeloperoxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Turnover of bacterial glutamine synthetase: oxidative inactivation precedes proteolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid microassays for the measurement of superoxide and hydrogen peroxide production by macrophages in culture using an automatic enzyme immunoassay reader

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disulphide reduction in lysosomes. The role of cysteine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigen presentation by liver sinusoidal lining cells after antigen exposure in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is enhanced free radical flux associated with increased intracellular proteolysis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteins damaged by oxygen radicals are rapidly degraded in extracts of red blood cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The specificity of thiourea, dimethylthiourea and dimethyl sulphoxide as scavengers of hydroxyl radicals. Their protection of alpha 1-antiproteinase against inactivation by hypochlorous acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cells process exogenous proteins for recognition by cytotoxic T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of NCO-700, an inhibitor of thiol protease, on reactive oxygen production by chemotactic peptide-stimulated rabbit peripheral granulocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N,N'-dimethylthiourea dioxide formation from N,N'-dimethylthiourea reflects hydrogen peroxide concentrations in simple biological systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antioxidant action of taurine, hypotaurine and their metabolic precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of proteinase-mediated degradation of proteins modified by chlorination

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cysteine-specific lysosomal transport system provides a major route for the delivery of thiol to human fibroblast lysosomes: possible role in supporting lysosomal proteolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of hypochlorite injury of target cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different roles for thiol and aspartyl proteases in antigen presentation of ovalbumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavonoids as antioxidants: determination of radical-scavenging efficiencies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein degradation as an index of oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of disulfide bonds during antigen processing: evidence from a thiol-dependent insulin determinant

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of disulfide bonds within lysosomes is a key step in antigen processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of immunogenic properties of ovalbumin as a result of its chlorination

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eosinophil as antigen-presenting cell: activation of T cell clones and T cell hybridoma by eosinophils after antigen processing.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of trinitrophenyl-specific humoral response to TNP proteins as the result of carrier chlorination

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acidification and disulfide reduction can be sufficient to allow intact proteins to bind class II MHC.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of chlorination by human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophils degrade subendothelial matrices in the presence of alpha-1-proteinase inhibitor. Cooperative use of lysosomal proteinases and oxygen metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of lysozyme by macrophages: identification of the determinant recognized by two T-cell hybridomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

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Catalase in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

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65 The use of selective free radical probes to study active sites in enzymes and viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three forms of thiol proteinase inhibitor from rat liver formed depending on the oxidation-reduction state of a sulfhydryl group

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine Kupffer cells. Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9824492

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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