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English
The amyloidogenicity of gelsolin is controlled by proteolysis and pH
scientific article published on 01 May 1999
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
title
The amyloidogenicity of gelsolin is controlled by proteolysis and pH
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
main subject
proteolysis
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author name string
Ratnaswamy G
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
Koepf E
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
Bekele H
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
Yin H
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
Kelly JW
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
publication date
1 May 1999
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
published in
Chemistry and Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
volume
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
issue
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
page(s)
293-304
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
cites work
Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gelsolin: calcium- and polyphosphoinositide-regulated actin-modulating protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deconstructing gelsolin: identifying sites that mimic or alter binding to actin and phosphoinositides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
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inferred from DOI database lookup
The Extracellular Actin-Scavenger System and Actin Toxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gelsolin-related familial amyloidosis, Finnish type (FAF), and its variants found worldwide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In pursuit of the molecular structure of amyloid plaque: new technology provides unexpected and critical information
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous β-sheet helix
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Examination of the Structure of the Transthyretin Amyloid Fibril by Image Reconstruction from Electron Micrographs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alternative conformations of amyloidogenic proteins govern their behavior
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The crystal structure of plasma gelsolin: implications for actin severing, capping, and nucleation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cells of the neuronal lineage play a major role in the generation of amyloid precursor fragments in gelsolin-related amyloidosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitative evaluation of congo red binding to amyloid-like proteins with a beta-pleated sheet conformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fibril formation by primate, rodent, and Dutch-hemorrhagic analogues of Alzheimer amyloid beta-protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resolution of the fluorescence excitation spectrum of indole into the 1La and 1Lb excitation bands
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of acid-induced folding of proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Classification of acid denaturation of proteins: intermediates and unfolded states
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformational states of beta-lactamase: molten-globule states at acidic and alkaline pH with high salt
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gelsolin variant (Asn-187) in familial amyloidosis, Finnish type
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation in gelsolin gene in Finnish hereditary amyloidosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid protein in familial amyloidosis (Finnish type) is homologous to gelsolin, an actin-binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Finnish hereditary amyloidosis is caused by a single nucleotide substitution in the gelsolin gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Finnish hereditary amyloidosis. Amino acid sequence homology between the amyloid fibril protein and human plasma gelsoline
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toward understanding the pathogenic mechanisms in gelsolin-related amyloidosis: in vitro expression reveals an abnormal gelsolin fragment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro expression analysis shows that the secretory form of gelsolin is the sole source of amyloid in gelsolin-related amyloidosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantification of serum and cerebrospinal fluid gelsolin in familial amyloidosis, Finnish type (AGel)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Demonstration of a circulating 65K gelsolin variant specific for familial amyloidosis, Finnish type
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transthyretin mutation Leu-55-Pro significantly alters tetramer stability and increases amyloidogenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of Lethal and Nonlethal Transthyretin Variants and Their Relationship to Amyloid Disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective localization of murine ApoSAA1/SAA2in endosomes-lysosomes in activated macrophages and their degradation products
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of pH and insulin on fibrillogenesis of islet amyloid polypeptide in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
pH-dependent structural transitions of Alzheimer amyloid peptides
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Localisation of islet amyloid polypeptide (IAPP) in pancreatic islets of transgenic mice expressing the human or rat IAPP gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endosome-lysosomes, ubiquitin and neurodegeneration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Observation of metastable Abeta amyloid protofibrils by atomic force microscopy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid fibril formation and protein misassembly: a structural quest for insights into amyloid and prion diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Guanidine hydrochloride-induced denaturation and refolding of transthyretin exhibits a marked hysteresis: equilibria with high kinetic barriers
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
A detergent-insoluble membrane compartment contains A beta in vivo
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
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7 January 2021
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inferred from DOI database lookup
Inhibition of amyloid formation: a strategy to delay the onset of Alzheimer's disease.
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Structural neurology: are seeds at the root of neuronal degeneration?
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of the Alzheimer amyloid beta protein by normal proteolytic processing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's disease: genotypes, phenotypes, and treatments
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
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7 January 2021
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inferred from DOI database lookup
Recombinant human retinol-binding protein refolding, native disulfide formation, and characterization
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
The oxidative folding of proteins by disulfide plus thiol does not correlate with redox potential
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-5521%2899%2980075-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-5521(99)80075-1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
PubMed publication ID
10322122
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10322122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
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