(Q77744045)

English

Synthesis of a new class of camptothecin derivatives, the long-chain fatty acid esters of 10-hydroxycamptothecin, as a potent prodrug candidate, and their in vitro metabolic conversion by carboxylesterases

scientific article published on 01 March 1998

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Synthesis of a new class of camptothecin derivatives, the long-chain fatty acid esters of 10-hydroxycamptothecin, as a potent prodrug candidate, and their in vitro metabolic conversion by carboxylesterases (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Masakiyo Hosokawa

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

author name string

H Takayama

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

A Watanabe

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

K Chiba

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

T Satoh

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

N Aimi

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

publication date

1 March 1998

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Bioorganic & Medicinal Chemistry Letters

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

415-418

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2898%2900039-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase I and pharmacologic study of oral topotecan administered twice daily for 21 days to adult patients with solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2898%2900039-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and antitumor activity of 20(S)-camptothecin derivatives: A-ring modified and 7,10-disubstituted camptothecins

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2898%2900039-0

7 January 2021

based on heuristic

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Phase I-II study of irinotecan hydrochloride combined with cisplatin in patients with advanced gastric cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2898%2900039-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Metabolic activation of CPT-11, 7-ethyl-10-[4-(1-piperidino)-1- piperidino]carbonyloxycamptothecin, a novel antitumor agent, by carboxylesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2898%2900039-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by Human Liver Carboxylesterase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2898%2900039-0

7 January 2021

based on heuristic

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Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2898%2900039-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Drug delivery systems. 2. Camptothecin 20-O-poly(ethylene glycol) ester transport forms

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2898%2900039-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation and partial synthesis of 3(R)- and 3(S)-deoxypumiloside; structural revision of the key metabolite from the camptothecin producing plant, Ophiorrhiza pumila

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2898%2900039-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Constituents of regenerated plants of Ophiorrhiza pumila; formation of a new glycocamptothecin and predominant formation of (3R)-deoxypumiloside over (3S)-congener

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2898%2900039-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Ethyl substitution at the 7 position extends the half-life of 10-hydroxycamptothecin in the presence of human serum albumin

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2898%2900039-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0960-894X(98)00039-0

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9871589%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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