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English
Molecular basis of receptor/G-protein-coupling selectivity
scientific article published on 01 December 1998
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9888696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9888696%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Molecular basis of receptor/G-protein-coupling selectivity
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9888696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9888696%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
author name string
J Wess
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9888696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9888696%20AND%20SRC:MED&resulttype=core&format=json
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8 December 2019
publication date
1 December 1998
1 reference
stated in
Europe PubMed Central
PubMed ID
9888696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9888696%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
published in
Pharmacology & Therapeutics
1 reference
stated in
Europe PubMed Central
PubMed ID
9888696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9888696%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
volume
80
1 reference
stated in
Europe PubMed Central
PubMed ID
9888696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9888696%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
page(s)
231-264
1 reference
stated in
Europe PubMed Central
PubMed ID
9888696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9888696%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed ID
9888696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9888696%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
cites work
Modulation of GDP release from transducin by the conserved Glu134-Arg135 sequence in rhodopsin
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Transducin-alpha C-terminal peptide binding site consists of C-D and E-F loops of rhodopsin
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Crossref
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Antisense knockouts: molecular scalpels for the dissection of signal transduction
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C-terminal truncation of the neurokinin-2 receptor causes enhanced and sustained agonist-induced signaling. Role of receptor phosphorylation in signal attenuation
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Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study
1 reference
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Crossref
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1 reference
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The probable arrangement of the helices in G protein-coupled receptors.
1 reference
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Crossref
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Structure and function of receptors coupled to G proteins
1 reference
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7 January 2021
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An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors
1 reference
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Crossref
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7 January 2021
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Reconstitution of receptors and GTP-binding regulatory proteins (G proteins) in Sf9 cells. A direct evaluation of selectivity in receptor.G protein coupling
1 reference
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Crossref
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Mapping of single amino acid residues required for selective activation of Gq/11 by the m3 muscarinic acetylcholine receptor
1 reference
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Insertion mutagenesis as a tool to predict the secondary structure of a muscarinic receptor domain determining specificity of G-protein coupling
1 reference
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How receptors talk to trimeric G proteins
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Dynamic palmitoylation of G-protein-coupled receptors in eukaryotic cells.
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Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid
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Muscarinic m1 receptor-stimulated adenylate cyclase activity in Chinese hamster ovary cells is mediated by Gs alpha and is not a consequence of phosphoinositidase C activation
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Structure-function of muscarinic receptor coupling to G proteins. Random saturation mutagenesis identifies a critical determinant of receptor affinity for G proteins
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Expression of the human 5-hydroxytryptamine1A receptor in Sf9 cells. Reconstitution of a coupled phenotype by co-expression of mammalian G protein subunits
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Characterization of rhodopsin mutants that bind transducin but fail to induce GTP nucleotide uptake. Classification of mutant pigments by fluorescence, nucleotide release, and flash-induced light-scattering assays.
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7 January 2021
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid GDP release from Gs alpha in patients with gain and loss of endocrine function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of the V2 vasopressin receptor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Residues in the fifth membrane-spanning segment of the dopamine D2 receptor exposed in the binding-site crevice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping the binding-site crevice of the dopamine D2 receptor by the substituted-cysteine accessibility method
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive activation of the beta2 adrenergic receptor alters the orientation of its sixth membrane-spanning segment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The function of a highly-conserved arginine residue in activation of the muscarinic M1 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NMR and circular dichroism studies of synthetic peptides derived from the third intracellular loop of the beta-adrenoceptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformation of a beta-adrenoceptor-derived signal transducing peptide as inferred by circular dichroism and 1H NMR spectroscopy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specificity of interaction between receptor and G protein: use of antisense techniques to relate G-protein subunits to function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the receptor binding domain of Gpa1p, the G(alpha) subunit involved in the yeast pheromone response pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coupling of human D-1 dopamine receptors to different guanine nucleotide binding proteins. Evidence that D-1 dopamine receptors can couple to both Gs and G(o).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficient interaction with a receptor requires a specific type of prenyl group on the G protein gamma subunit
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adrenergic receptors as models for G protein-coupled receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel system that reports the G-proteins linked to a given receptor: a study of type 3 somatostatin receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three cytoplasmic loops of rhodopsin interact with transducin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular basis of receptor/G protein coupling selectivity studied by coexpression of wild type and mutant m2 muscarinic receptors with mutant G alpha(q) subunits
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The N-terminal extension of Galphaq is critical for constraining the selectivity of receptor coupling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic analysis of receptor-Galphaq coupling selectivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of Asp578 in maintaining the inactive conformation of the human lutropin/choriogonadotropin receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transmembrane regions V and VI of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of alpha- and betagamma-subunits of G0 to beta1-adrenoceptor in sealed unilamellar lipid vesicles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptors for VIP, PACAP, secretin, GRF, glucagon, GLP-1, and other members of their new family of G protein-linked receptors: structure-function relationship with special reference to the human VIP-1 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 2.0 A crystal structure of a heterotrimeric G protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of receptor-activated G proteins: selective immunoprecipitation of photolabeled G-protein alpha subunits.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evolutionarily conserved Galphabetagamma binding surfaces support a model of the G protein-receptor complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Different single receptor domains determine the distinct G protein coupling profiles of members of the vasopressin receptor family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanisms involved in muscarinic acetylcholine receptor-mediated G protein activation studied by insertion mutagenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of the aspartate-arginine-tyrosine triad in the m1 muscarinic receptor: mutations of aspartate 122 and tyrosine 124 decrease receptor expression but do not abolish signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G protein heterotrimer Galpha13beta1gamma3 couples the angiotensin AT1A receptor to increases in cytoplasmic Ca2+ in rat portal vein myocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct functions of Gq and G11 proteins in coupling alpha1-adrenoreceptors to Ca2+ release and Ca2+ entry in rat portal vein myocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potent peptide analogues of a G protein receptor-binding region obtained with a combinatorial library
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A multigene family encoding a diverse array of putative pheromone receptors in mammals.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Truncation of the thyrotropin-releasing hormone receptor carboxyl tail causes constitutive activity and leads to impaired responsiveness in Xenopus oocytes and AtT20 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of Transducin with Light-activated Rhodopsin Protects It from Proteolytic Digestion by Trypsin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential coupling of m2 and m4 muscarinic receptors to inhibition of adenylyl cyclase by Gi alpha and G(o)alpha subunits
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal sorting by G-protein-linked receptors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical approaches to examine the specificity of interactions between receptors and guanine nuclotide binding proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific Gq protein involvement in muscarinic M3 receptor-induced phosphatidylinositol hydrolysis and Ca2+ release in mouse duodenal myocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor regulation of G-protein palmitoylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multisite contacts involved in coupling of the beta-adrenergic receptor with the stimulatory guanine-nucleotide-binding regulatory protein. Structural and functional studies by beta-receptor-site-specific synthetic peptides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The second intracellular loop of the alpha2-adrenergic receptors determines subtype-specific coupling to cAMP production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heterotrimeric G proteins: organizers of transmembrane signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane organization in G-protein mechanisms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of the mouse 5-HT7 receptor: importance of the third intracellular loop for receptor-G-protein interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a Gs activator region of the β2-adrenergic receptor that is autoregulated via protein kinase A-dependent phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Palmitoylation of human endothelinB. Its critical role in G protein coupling and a differential requirement for the cytoplasmic tail by G protein subtypes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of A2a adenosine receptor domains involved in selective coupling to Gs. Analysis of chimeric A1/A2a adenosine receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A common step for signal transduction in G protein-coupled receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor and betagamma binding sites in the alpha subunit of the retinal G protein transducin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of carboxyl-terminal mutagenesis of Gt alpha on rhodopsin and guanine nucleotide binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
X-ray structure of bacteriorhodopsin at 2.5 angstroms from microcrystals grown in lipidic cubic phases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and characterization of the signal transduction of four splice variants of the human pituitary adenylate cyclase activating polypeptide receptor. Evidence for dual coupling to adenylate cyclase and phospholipase C.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the alpha1b-adrenergic receptor is initiated by disruption of an interhelical salt bridge constraint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of low affinity N-formyl peptide receptors to G protein. Characterization of a novel inactive receptor intermediate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activating mutations of rhodopsin and other G protein-coupled receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural and functional relationships of heterotrimeric G-proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of phosphoinositide-specific phospholipase C isozymes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutively active mutants of rhodopsin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein modification. Palmitoylation in G-protein signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A domain for G protein coupling in carboxyl-terminal tail of rat angiotensin II receptor type 1A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of a highly conserved aspartate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Projection structure of rhodopsin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Splice variants of the human EP3 receptor for prostaglandin E2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A C-terminally truncated human parathyroid hormone receptor is functional and activates multiple G proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Locating ligand-binding sites in 7TM receptors by protein engineering.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gonadotrophin-releasing hormone receptor agonist-mediated down-regulation of Gq alpha/G11 alpha (pertussis toxin-insensitive) G proteins in alpha T3-1 gonadotroph cells reflects increased G protein turnover but not alterations in mRNA levels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G protein-coupled receptor structure and function: the impact of disease-causing mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping of G protein coupling sites of the angiotensin II type 1 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two distinct pathways for histamine H2 receptor down-regulation. H2 Leu124 --> Ala receptor mutant provides evidence for a cAMP-independent action of H2 agonists
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of a G-protein beta gamma dimer at 2.1A resolution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted inactivation of alphai2 or alphai3 disrupts activation of the cardiac muscarinic K+ channel, IK+Ach, in intact cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential signal transduction by five splice variants of the PACAP receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defects in G protein-coupled signal transduction in human disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Gq/11 by the Gonadotropin-Releasing Hormone Receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and function of G protein-coupled receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complexity and diversity of mammalian adenylyl cyclases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A point mutation of the alpha 2-adrenoceptor that blocks coupling to potassium but not calcium currents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis of G protein specificity of human endothelin receptors. A study with endothelinA/B chimeras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular identification of guanine-nucleotide-binding regulatory proteins which couple to endothelin receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor and membrane interaction sites on Gbeta. A receptor-derived peptide binds to the carboxyl terminus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of amino- and carboxyl-terminal regions of G(alphaZ) in the recognition of Gi-coupled receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Arrangement of rhodopsin transmembrane α-helices
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of deletion and truncation mutants of the rat glucagon receptor. Seven transmembrane segments are necessary for receptor transport to the plasma membrane and glucagon binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G alpha(o) is necessary for muscarinic regulation of Ca2+ channels in mouse heart
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular Architecture of G Protein-Coupled Receptors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The thrombin receptor second cytoplasmic loop confers coupling to Gq-like G proteins in chimeric receptors. Additional evidence for a common transmembrane signaling and G protein coupling mechanism in G protein-coupled receptors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a domain in the angiotensin II type 1 receptor determining Gq coupling by the use of receptor chimeras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Basic amino acids at the C-terminus of the third intracellular loop are required for the activation of phospholipase C by cholecystokinin-B receptors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ribozyme-mediated suppression of the G protein gamma7 subunit suggests a role in hormone regulation of adenylylcyclase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation and depalmitoylation of Gs alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipid modifications of trimeric G proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional characterization of five V2 vasopressin receptor gene mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular biology of muscarinic acetylcholine receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a small intracellular region of the muscarinic m3 receptor as a determinant of selective coupling to PI turnover.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional role of proline and tryptophan residues highly conserved among G protein-coupled receptors studied by mutational analysis of the m3 muscarinic receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Measurement of receptor-stimulated guanosine 5'-O-(gamma-thio)triphosphate binding by G proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degradation of G11 alpha/Gq alpha is accelerated by agonist occupancy of alpha 1A/D, alpha 1B, and alpha 1C adrenergic receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential targeting and retention of G protein-coupled receptors in polarized epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G protein-coupled signal transduction pathways for interleukin-8
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
First intracellular loop of the human cholecystokinin-A receptor is essential for cyclic AMP signaling in transfected HEK-293 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and function in rhodopsin. Cysteines 65 and 316 are in proximity in a rhodopsin mutant as indicated by disulfide formation and interactions between attached spin labels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and function in rhodopsin. Single cysteine substitution mutants in the cytoplasmic interhelical E-F loop region show position-specific effects in transducin activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the prenyl group on the G protein gamma subunit in coupling trimeric G proteins to A1 adenosine receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three-Dimensional Structure of the Cytoplasmic Face of the G Protein Receptor Rhodopsin†
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The First and Second Cytoplasmic Loops of the G-Protein Receptor, Rhodopsin, Independently Form β-Turns†
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A general method for mapping tertiary contacts between amino acid residues in membrane-embedded proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The AT2 receptor selectively associates with Gialpha2 and Gialpha3 in the rat fetus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G protein subunits and the stimulation of phospholipase C by Gs-and Gi-coupled receptors: Lack of receptor selectivity of Galpha(16) and evidence for a synergic interaction between Gbeta gamma and the alpha subunit of a receptor activated G protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900030-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0163-7258(98)00030-8
1 reference
stated in
Europe PubMed Central
PubMed ID
9888696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9888696%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
PubMed ID
9888696
1 reference
stated in
Europe PubMed Central
PubMed ID
9888696
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9888696%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
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