(Q77796455)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889383%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

review article

1 reference

title

Structure and function of the uncoupling protein from brown adipose tissue (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889383%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

author name string

M Klingenberg

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889383%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

S G Huang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889383%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

language of work or name

English

0 references

publication date

1 January 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889383%20AND%20SRC:MED&resulttype=core&format=json

Biochimica et Biophysica Acta

8 December 2019

number of pages

26

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889383%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

volume

1415

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889383%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

page(s)

271-296

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889383%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889383%20AND%20SRC:MED&resulttype=core&format=json

Brown adipose tissue mitochondria

8 December 2019

cites work

1 reference

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Thermogenic mechanisms in brown fat

7 January 2021

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Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

7 January 2021

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Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression

7 January 2021

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Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin

7 January 2021

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Isolation of the uncoupling protein from brown adipose tissue mitochondria

7 January 2021

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Characteristics of the isolated purine nucleotide binding protein from brown fat mitochondria

7 January 2021

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Binding of guanine nucleotides to the outer surface of the inner membrane of guinea pig brown fat mitochondria in correlation with the thermogenic activity of the tissue

7 January 2021

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Hamster Brown-Adipose-Tissue Mitochondria. Purine Nucleotide Control of the Ion Conductance of the Inner Membrane, the Nature of the Nucleotide Binding Site

7 January 2021

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Brown-Adipose-Tissue Mitochondria: Photoaffinity Labelling of the Regulatory Site of Energy Dissipation

7 January 2021

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Purification of the carboxy‐atractylate binding protein from mitochondria

7 January 2021

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The uncoupling protein from brown fat mitochondria is related to the mitochondrial ADP/ATP carrier. Analysis of sequence homologies and of folding of the protein in the membrane.

7 January 2021

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Solute carriers involved in energy transfer of mitochondria form a homologous protein family

7 January 2021

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Mitochondrial carrier proteins

7 January 2021

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Extension of the mitochondrial transporter super-family: sequences of five members from the nematode worm, Caenorhabditis elegans.

7 January 2021

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The mitochondrial carrier family of transport proteins: structural, functional, and evolutionary relationships

7 January 2021

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Nucleotide sequence of a cDNA encoding bovine brown fat uncoupling protein. Homology with ADP binding site of ADP/ATP carrier.

7 January 2021

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Human uncoupling protein gene: structure, comparison with rat gene, and assignment to the long arm of chromosome 4.

7 January 2021

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Rabbit brown adipose tissue uncoupling protein MRNA: use of only one of two polyadenylation signals in its processing.

7 January 2021

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The uncoupling protein from brown adipose tissue mitochondria is a dimer. A hydrodynamic study

7 January 2021

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The uncoupling protein dimer can form a disulfide cross-link between the mobile C-terminal SH groups

7 January 2021

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In the uncoupling protein from brown adipose tissue the C-terminus protrudes to the c-side of the membrane as shown by tryptic cleavage

7 January 2021

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Molecular weight and hydrodynamic parameters of the adenosine 5'-diphosphate-adenosine 5'-triphosphate carrier in Triton X-100

7 January 2021

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Membrane protein oligomeric structure and transport function

7 January 2021

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The phosphate carrier from yeast mitochondria. Dimerization is a prerequisite for function.

7 January 2021

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Internal sequence repeats and the path of polypeptide in mitochondrial ADP/ATP translocase

7 January 2021

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Infrared spectroscopic studies of detergent-solubilized uncoupling protein from brown-adipose-tissue mitochondria

7 January 2021

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Brown-Adipose-Tissue Mitochondria. The Influence of Albumin and Nucleotides on Passive Ion Permeabilities

7 January 2021

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The influence of respiration and ATP hydrolysis on the proton-electrochemical gradient across the inner membrane of rat-liver mitochondria as determined by ion distribution.

7 January 2021

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Inter-Relationships between Proton Electrochemical Gradient, Adenine-Nucleotide Phosphorylation Potential and Respiration, during Substrate-Level and Oxidative Phosphorylation by Mitochondria from Brown Adipose Tissue of Cold-Adapted Guinea-Pigs

7 January 2021

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Stoicheiometries of Proton Translocation by Mitochondria

7 January 2021

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A re-evaluation of the role of fatty acids in the physiological regulation of the proton conductance of brown adipose tissue mitochondria

7 January 2021

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Molecular mechanism of uncoupling in brown adipose tissue mitochondria. The non-identity of proton and chloride conducting pathways

7 January 2021

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Brown-adipose-tissue mitochondria: the regulation of the 32000-Mr uncoupling protein by fatty acids and purine nucleotides

7 January 2021

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The acute regulation of mitochondrial proton conductance in cells and mitochondria from the brown fat of cold-adapted and warm-adapted guinea pigs

7 January 2021

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The Structural Specificity of the Nucleotide-Binding Site and the Reversible Nature of the Inhibition of Proton Conductance Induced by Bound Nucleotides in Brown-Adipose-Tissue Mitochondria

7 January 2021

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Reconstitution of an H+ translocator, the "uncoupling protein" from brown adipose tissue mitochondria, in phospholipid vesicles

7 January 2021

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Partial purification and functional reconstitution of GDP sensitive brown adipose tissue mitochondria uncoupling protein using octyl glucoside

7 January 2021

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An improved procedure for reconstitution of the uncoupling protein and in-depth analysis of H+/OH- transport

7 January 2021

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Mutagenesis of the uncoupling protein of brown adipose tissue. Neutralization Of E190 largely abolishes pH control of nucleotide binding

7 January 2021

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Fatty acids as acute regulators of the proton conductance of hamster brown-fat mitochondria

7 January 2021

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Quantification of fatty acid activation of the uncoupling protein in brown adipocytes and mitochondria from the guinea-pig

7 January 2021

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Studies on Norepinephrine‐Induced Efflux of Free Fatty Acid from Hamster Brown‐Adipose‐Tissue Cells

7 January 2021

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Nucleotide binding to uncoupling protein. Mechanism of control by protonation.

7 January 2021

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Influence of fatty acids on energy metabolism. 2. Kinetics of changes in metabolic rates and changes in subcellular adenine nucleotide contents and pH gradients following addition of octanoate and oleate in perfused rat liver

7 January 2021

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A structure-activity study of fatty acid interaction with mitochondrial uncoupling protein

7 January 2021

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A NMR study of the ionization of fatty acids, fatty amines and N-acylamino acids incorporated in phosphatidylcholine vesicles

7 January 2021

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Chloride channel properties of the uncoupling protein from brown adipose tissue mitochondria: a patch-clamp study

7 January 2021

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On the mechanism of fatty acid-induced proton transport by mitochondrial uncoupling protein

7 January 2021

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Control of uncoupling protein in brown-fat mitochondria by purine nucleotides. Chemical modification by diazobenzenesulfonate

7 January 2021

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Sulfonates are low-affinity ligands for the GDP-binding site of brown-fat mitochondria

7 January 2021

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General concept for ion translocation by halobacterial retinal proteins: the isomerization/switch/transfer (IST) model

7 January 2021

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The Effective Proton Conductance of the Inner Membrane of Mitochondria from Brown Adipose Tissue. Dependency on Proton Electrochemical Potential Gradient

7 January 2021

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Local-access model for proton transfer in bacteriorhodopsin

7 January 2021

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Existence of a proton transfer chain in bacteriorhodopsin: participation of Glu-194 in the release of protons to the extracellular surface

7 January 2021

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Carboxyl group protonation upon reduction of the Paracoccus denitrificans cytochrome c oxidase: direct evidence by FTIR spectroscopy

7 January 2021

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Mechanism and evolution of the uncoupling protein of brown adipose tissue

7 January 2021

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H+ transport by uncoupling protein (UCP-1) is dependent on a histidine pair, absent in UCP-2 and UCP-3

7 January 2021

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Fatty acid binding site of the mitochondrial uncoupling protein. Demonstration of its existence by EPR spectroscopy of 5-DOXYL-stearic acid

7 January 2021

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Photoactivated azido fatty acid irreversibly inhibits anion and proton transport through the mitochondrial uncoupling protein.

7 January 2021

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Photoaffinity labelling of the mitochondrial uncoupling protein by [3H]azido fatty acid affects the anion channel

7 January 2021

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The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

7 January 2021

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Fatty acid circuit as a physiological mechanism of uncoupling of oxidative phosphorylation

7 January 2021

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The state of ADP or ATP fixed to the mitochondria by bongkrekate

7 January 2021

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Inactive fatty acids are unable to flip-flop across the lipid bilayer

7 January 2021

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Nucleotide binding assay for uncoupling protein from brown fat mitochondria

7 January 2021

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Fluorescent nucleotide derivatives as specific probes for the uncoupling protein: thermodynamics and kinetics of binding and the control by pH

7 January 2021

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Two-stage nucleotide binding mechanism and its implications to H+ transport inhibition of the uncoupling protein from brown adipose tissue mitochondria.

7 January 2021

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The regulation of the proton conductance of brown fat mitochondria. Identification of functional and non-functional nucleotide-binding sites

7 January 2021

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Nature of the masking of nucleotide-binding sites in brown adipose tissue mitochondria. Involvement of endogenous adenosine triphosphate

7 January 2021

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Slow-phase kinetics of nucleotide binding to the uncoupling protein from brown adipose tissue mitochondria

7 January 2021

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Effect of acclimation temperature on the concentration of uncoupling protein and GDP binding in rat brown fat mitochondria

7 January 2021

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Dialectics in carrier research: the ADP/ATP carrier and the uncoupling protein

7 January 2021

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Isolation of the ADP, ATP carrier as the carboxyatractylate . protein complex from mitochondria

7 January 2021

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ADP/ATP carrier and uncoupling protein

7 January 2021

1 reference

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Interaction of fluorescent 3'-[1,5-(dimethylamino)naphthoyl]adenine nucleotides with the solubilized ADP/ATP carrier

7 January 2021

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Characteristics of the uncoupling protein from brown-fat mitochondria

7 January 2021

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A study of GDP binding to purified thermogenin protein from brown adipose tissue

7 January 2021

1 reference

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Effect of pH and MgCl2 on the binding of purine nucleotides to the uncoupling protein in membrane particles from brown fat mitochondria

7 January 2021

1 reference

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Identification of the pH sensor for nucleotide binding in the uncoupling protein from brown adipose tissue

7 January 2021

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Increased purine nucleotide binding, altered polypeptide composition, and thermogenesis in brown adipose tissue mitochondria of cold-acclimated rats

7 January 2021

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[3H]GDP binding and thermogenin amount in brown adipose tissue mitochondria from cold-exposed rats

7 January 2021

1 reference

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Apparent unmasking of [3H]GDP binding in rat brown-fat mitochondria is due to mitochondrial swelling

7 January 2021

1 reference

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Acute effects of a beta-adrenoceptor agonist (BRL 26830A) on rat brown-adipose-tissue mitochondria. Increased GDP binding and GDP-sensitive proton conductance without changes in the concentration of uncoupling protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Regulation of GDP binding and uncoupling-protein concentration in brown-adipose-tissue mitochondria. The effects of cold-acclimation, warm-reacclimation and noradrenaline

7 January 2021

1 reference

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Parallel regression of cold-induced changes in ultrastructure, composition, and properties of brown adipose tissue mitochondria during recovery of rats from acclimation to cold

7 January 2021

1 reference

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Evidence for unmasking of rat brown-adipose-tissue mitochondrial GDP-binding sites in response to acute cold exposure. Effects of washing with albumin on GDP binding

7 January 2021

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The mitochondrial uncoupling protein from guinea-pig brown adipose tissue. Synchronous increase in structural and functional parameters during cold-adaptation

7 January 2021

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Norepinephrine-Induced Shift in Levels of Adenosine 3':5'-monophosphate and ATP Parallel to Increased Respiratory Rate and Lipolysis in Isolated Hamster Brown-Fat Cells

7 January 2021

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Brown Adipose Tissue Mitochondria Recoupling Caused by Substrate Level Phosphorylation and Extramitochondrial Adenosine Phosphates

7 January 2021

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Effect of hydrophobic sulphydryl reagents on the uncoupling protein and inner-membrane anion channel of brown-adipose-tissue mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Chemical modification of the brown-fat-mitochondrial uncoupling protein with tetranitromethane and N-ethylmaleimide. A cysteine residue is implicated in the nucleotide regulation of anion permeability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Reconstitution of purified brown adipose tissue mitochondria uncoupling protein: demonstration of separate identity of nucleotide binding and proton translocation sites by chemical probes

7 January 2021

1 reference

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Sulfhydryl groups are involved in H+ translocation via the uncoupling protein of brown adipose tissue mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

In the uncoupling protein (UCP-1) His-214 is involved in the regulation of purine nucleoside triphosphate but not diphosphate binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Stable expression of functional mitochondrial uncoupling protein in Chinese hamster ovary cells.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Expression of the brown fat mitochondria uncoupling protein in Xenopus oocytes and import into mitochondrial membrane

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Identification of a novel gene encoding the yeast mitochondrial dicarboxylate transport protein via overexpression, purification, and characterization of its protein product

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Characterization of the S3 subsite specificity of cathepsin B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Yeast mitochondrial phosphate transport protein expressed in Escherichia coli. Site-directed mutations at threonine-43 and at a similar location in the second tandem repeat (isoleucine-141)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Abundant bacterial expression and reconstitution of an intrinsic membrane-transport protein from bovine mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Functional expression of the rat brown adipose tissue uncoupling protein in Saccharomyces cerevisiae

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Cysteine residues are not essential for uncoupling protein function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Mapping of the nucleotide-binding sites in the ADP/ATP carrier of beef heart mitochondria by photolabeling with 2-azido[alpha-32P]adenosine diphosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

The ADP/ATP carrier from yeast (AAC-2) is uniquely suited for the assignment of the binding center by photoaffinity labeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Labeling of two different regions of the nucleotide binding site of the uncoupling protein from brown adipose tissue mitochondria with two ATP analogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Photoaffinity labeling of the nucleotide-binding site of the uncoupling protein from hamster brown adipose tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

The transmembrane arrangement of the ADP/ATP carrier as elucidated by the lysine reagent pyridoxal 5-phosphate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Identification by site-directed mutagenesis of three arginines in uncoupling protein that are essential for nucleotide binding and inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Activation of the uncoupling protein by fatty acids is modulated by mutations in the C-terminal region of the protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Site-directed mutagenesis of the yeast mitochondrial ADP/ATP translocator. Six arginines and one lysine are essential

7 January 2021

1 reference

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Probing the Role of Positive Residues in the ADP/ATP Carrier from Yeast. The Effect of Six Arginine Mutations on Oxidative Phosphorylation and AAC Expression†

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Probing the Role of Positive Residues in the ADP/ATP Carrier from Yeast. The Effect of Six Arginine Mutations on Transport and the Four ATP versus ADP Exchange Modes†

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

Uncoupling protein-3 expression in skeletal muscle and free fatty acids in obesity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

The mitochondrial uncoupling protein: structural and genetic studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

inferred from DOI database lookup

7 January 2021

based on heuristic

Role of UCP homologues in skeletal muscles and brown adipose tissue: mediators of thermogenesis or regulators of lipids as fuel substrate?

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2898%2900232-6

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0005-2736(98)00232-6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9889383%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference