(Q77959408)

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The effect of folate deficiency on the hprt mutational spectrum in Chinese hamster ovary cells treated with monofunctional alkylating agents

scientific article published on 01 June 1999

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scholarly article

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9 December 2019

The effect of folate deficiency on the hprt mutational spectrum in Chinese hamster ovary cells treated with monofunctional alkylating agents (English)

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Europe PubMed Central

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9 December 2019

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folate deficiency

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based on heuristic

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R F Branda

1

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Europe PubMed Central

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9 December 2019

A R Lafayette

2

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9 December 2019

J P O'Neill

3

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9 December 2019

J A Nicklas

4

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9 December 2019

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1 June 1999

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9 December 2019

Mutation Research

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9 December 2019

427

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9 December 2019

2

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9 December 2019

79-87

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9 December 2019

Nutritional factors in colorectal cancer risk: a case-control study in Majorca

1 reference

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7 January 2021

Alcohol, low-methionine--low-folate diets, and risk of colon cancer in men

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Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study

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Dietary folate protects against the development of macroscopic colonic neoplasia in a dose responsive manner in rats

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Folate and cancer: A review of the literature

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Reduced rate of DNA replication fork movement in megaloblastic anemia

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DNA double-strand breaks caused by replication arrest

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Deletions at stalled replication forks occur by two different pathways

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7 January 2021

Misincorporation of uracil into the DNA of folate- and B12-deficient HL60 cells

1 reference

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7 January 2021

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

1 reference

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7 January 2021

Uracil misincorporation in human DNA detected using single cell gel electrophoresis.

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7 January 2021

Repair of uracil residues closely spaced on the opposite strands of plasmid DNA results in double-strand break and deletion formation.

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7 January 2021

Diet-induced DNA damage and altered nucleotide metabolism in lymphocytes from methyl-donor-deficient rats

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7 January 2021

International Commission for Protection Against Environmental Mutagens and Carcinogens. Deoxyribonucleoside triphosphate levels: a critical factor in the maintenance of genetic stability

1 reference

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7 January 2021

Folate depletion impairs DNA excision repair in the colon of the rat.

1 reference

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7 January 2021

Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat

1 reference

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7 January 2021

Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene

1 reference

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7 January 2021

Demethylation of specific sites in the 5' region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expression

1 reference

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7 January 2021

Association of Marginal Folate Depletion With Increased Human Chromosomal Damage In Vivo: Demonstration by Analysis of Micronucleated Erythrocytes

1 reference

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7 January 2021

Nutritional folate deficiency augments the in vivo mutagenic and lymphocytotoxic activities of alkylating agents

1 reference

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7 January 2021

Multiplex DNA amplification and solid-phase direct sequencing for mutation analysis at the hprt locus in Chinese hamster cells

1 reference

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7 January 2021

Analysis of mutations occurring at the human hprt locus.

1 reference

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7 January 2021

Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents

1 reference

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7 January 2021

International Commission for Protection Against Environmental Mutagens and Carcinogens. The subtlety of alkylating agents in reactions with biological macromolecules

1 reference

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7 January 2021

Release of 7-methylguanine residues from alkylated DNA by extracts of Micrococcus luteus and Escherichia coli

1 reference

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7 January 2021

Human lymphoblasts contain DNA glycosylase activity excising N-3 and N-7 methyl and ethyl purines but not O6-alkylguanines or 1-alkyladenines

1 reference

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7 January 2021

Enzymatic release of 7-methylguanine from methylated DNA by rodent liver extracts

1 reference

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7 January 2021

Why do O6-alkylguanine and O4-alkylthymine miscode? The relationship between the structure of DNA containing O6-alkylguanine and O4-alkylthymine and the mutagenic properties of these bases

1 reference

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7 January 2021

Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents

1 reference

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7 January 2021

Effect of nucleotide excision repair on hprt gene mutations in rodent cells exposed to DNA ethylating agents

1 reference

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7 January 2021

Alkylation damage, DNA repair and mutagenesis in human cells

1 reference

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7 January 2021

Functional nucleotide excision repair is required for the preferential removal of N-ethylpurines from the transcribed strand of the dihydrofolate reductase gene of Chinese hamster ovary cells

1 reference

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7 January 2021

Methyl methanesulfonate-induced hprt mutation spectra in the Chinese hamster cell line CHO9 and its xrcc1-deficient derivative EM-C11.

1 reference

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7 January 2021

Structures and functions of DNA glycosylases

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7 January 2021

A review of the genotoxicity of 1-ethyl-1-nitrosourea

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7 January 2021

Comparison of mutation spectra induced by N-ethyl-N-nitrosourea in the hprt gene of Mer+ and Mer- diploid human fibroblasts.

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7 January 2021

Analysis of in vivo mutation induced by N-ethyl-N-nitrosourea in the hprt gene of rat lymphocytes

1 reference

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7 January 2021

DNA sequence analysis of hprt mutants persisting in peripheral blood of cynomolgus monkeys more than two years after ENU treatment

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7 January 2021

High frequency mutagenesis by a DNA methyltransferase

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7 January 2021

Identifiers

10.1016/S0027-5107(99)00095-0

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10393262%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10393262%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

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