(Q77984407)

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Non-thiazolidinedione antihyperglycaemic agents. Part 3: The effects of stereochemistry on the potency of alpha-methoxy-beta-phenylpropanoic acids

scientific article published on 01 May 1999

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10 December 2019

Non-thiazolidinedione antihyperglycaemic agents. Part 3: The effects of stereochemistry on the potency of alpha-methoxy-beta-phenylpropanoic acids (English)

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10 December 2019

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D Haigh

1

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10 December 2019

G Allen

2

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10 December 2019

H C Birrell

3

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10 December 2019

D R Buckle

4

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10 December 2019

B C Cantello

5

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10 December 2019

D S Eggleston

6

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10 December 2019

R C Haltiwanger

7

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10 December 2019

J C Holder

8

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10 December 2019

C A Lister

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10 December 2019

I L Pinto

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10 December 2019

H K Rami

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10 December 2019

J T Sime

12

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10 December 2019

S A Smith

13

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10 December 2019

J D Sweeney

14

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10 December 2019

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1 May 1999

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10 December 2019

Bioorganic & Medicinal Chemistry

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10 December 2019

7

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10 December 2019

5

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10 December 2019

821-830

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10 December 2019

Banting lecture 1988. Role of insulin resistance in human disease

1 reference

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Insulin resistance--mechanisms, syndromes, and implications

1 reference

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7 January 2021

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Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

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Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents.

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Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians

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Studies on antidiabetic agents. II. Synthesis of 5-[4-(1-methylcyclohexylmethoxy)-benzyl]thiazolidine-2,4-dione (ADD-3878) and its derivatives

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Reduction of Insulin Resistance in Obese and/or Diabetic Animals by 5-[4-(1-Methylcyclohexylmethoxy)benzyl]-thiazolidine-2,4-dione (ADD-3878, U-63,287, Ciglitazone), a New Antidiabetic Agent

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The synthesis of BRL 49653 - a novel and potent antihyperglycaemic agent

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[[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents

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Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone

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An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

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15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

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The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones

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Studies on antidiabetic agents. VI. Asymmetric transformation of (+/-)-5-[4-(1-methylcyclohexylmethoxy)benzyl]-2,4- thiazolidinedione(ciglitazone) with optically active 1-phenylethylamines

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Competing OH insertion and β-elimination in rhodium carbenoid reactions; synthesis of 2-alkoxy-3-arylpropanoates

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Insulin-induced translocation of glucose transporters to the plasma membrane precedes full stimulation of hexose transport

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Chiral inversion of 2-arylpropionic acid non-steroidal anti-inflammatory drugs--1. In vitro studies of ibuprofen and flurbiprofen

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Drug chirality: on the mechanism of R-aryl propionic acid class NSAIDs. Epimerization in humans and the clinical implications for the use of racemates

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Hypoglycemic activity of a series of alpha-alkylthio and alpha-alkoxy carboxylic acids related to ciglitazone

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Differential activation of peroxisome proliferator-activated receptors by eicosanoids.

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Identifiers

10.1016/S0968-0896(99)00034-6

1 reference

Europe PubMed Central

PubMed publication ID

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10 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

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10 December 2019

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