(Q77993738)

English

Actinomycin D as a novel SH2 domain ligand inhibits Shc/Grb2 interaction in B104-1-1 (neu*-transformed NIH3T3) and SAA (hEGFR-overexpressed NIH3T3) cells

scientific article published on 01 June 1999

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scholarly article

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10 December 2019

Actinomycin D as a novel SH2 domain ligand inhibits Shc/Grb2 interaction in B104-1-1 (neu*-transformed NIH3T3) and SAA (hEGFR-overexpressed NIH3T3) cells (English)

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10 December 2019

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H K Kim

1

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10 December 2019

J Y Nam

2

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10 December 2019

M Y Han

3

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10 December 2019

E K Lee

4

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10 December 2019

J D Choi

5

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10 December 2019

S H Bok

6

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10 December 2019

B M Kwon

7

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10 December 2019

publication date

1 June 1999

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10 December 2019

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10 December 2019

453

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10 December 2019

174-178

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10 December 2019

1-2

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10 December 2019

Regulatory mechanisms for ras proteins

1 reference

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21 January 2018

Association between GRB2/Sos and insulin receptor substrate 1 is not sufficient for activation of extracellular signal-regulated kinases by interleukin-4: implications for Ras activation by insulin

1 reference

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21 January 2018

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

1 reference

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21 January 2018

Dominant-negative mutants of Grb2 induced reversal of the transformed phenotypes caused by the point mutation-activated rat HER-2/Neu

1 reference

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21 January 2018

Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

1 reference

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21 January 2018

Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries

1 reference

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21 January 2018

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

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21 January 2018

Overexpression of EGFR and c-erbB2 causes enhanced cell migration in human breast cancer cells and NIH3T3 fibroblasts

1 reference

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21 January 2018

Selective inhibition of growth factor-stimulated mitogenesis by a cell-permeable Grb2-binding peptide

1 reference

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21 January 2018

Actinomycin D, C2 and VII, inhibitors of Grb2-SHC interaction produced by Streptomyces

1 reference

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21 January 2018

A screening method of SH2 domain ligands and blockers using a solid phase binding

1 reference

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21 January 2018

Actinomycin D treatment leads to differentiation and inhibits proliferation in rhabdomyosarcoma cells

1 reference

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21 January 2018

Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode

1 reference

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Crystal structure of the 2:1 complex between d(GAAGCTTC) and the anticancer drug actinomycin D

1 reference

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21 January 2018

An alternative to phosphotyrosine-containing motifs for binding to an SH2 domain

1 reference

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21 January 2018

Taxol induces tyrosine phosphorylation of Shc and its association with Grb2 in murine RAW 264.7 cells

1 reference

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21 January 2018

The Ras antagonist S-farnesylthiosalicylic acid induces inhibition of MAPK activation

1 reference

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Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors.

1 reference

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21 January 2018

L-O-(2-malonyl)tyrosine: a new phosphotyrosyl mimetic for the preparation of Src homology 2 domain inhibitory peptides

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21 January 2018

Nonphosphorylated peptide ligands for the Grb2 Src homology 2 domain

1 reference

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21 January 2018

Early estrogen-induced metabolic changes and their inhibition by actinomycin D and cycloheximide in human breast cancer cells: 31P and 13C NMR studies

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21 January 2018

Binding of actinomycin D to DNA oligomers of CXG trinucleotide repeats

1 reference

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21 January 2018

Mitogen-activated protein (MAP) kinase is regulated by the MAP kinase phosphatase (MKP-1) in vascular smooth muscle cells. Effect of actinomycin D and antisense oligonucleotides

1 reference

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21 January 2018

Oncogene products as therapeutic targets for cancer

1 reference

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7 January 2021

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Identifiers

10.1016/S0014-5793(99)00710-3

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10 December 2019

1 reference

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10 December 2019

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