(Q78045280)

English

Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7alpha-hydroxylase in cultured rat hepatocytes and in vivo in the rat

scientific article published on 01 August 1999

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10421659%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7alpha-hydroxylase in cultured rat hepatocytes and in vivo in the rat (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10421659%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

3

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10 December 2019

7

1 reference

Europe PubMed Central

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10 December 2019

author name string

S M Post

1

1 reference

Europe PubMed Central

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10 December 2019

J P Zoeteweij

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10421659%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

E C de Wit

4

1 reference

Europe PubMed Central

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10 December 2019

R Havinga

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10421659%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

F Kuipers

6

1 reference

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10 December 2019

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publication date

1 August 1999

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10421659%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10421659%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

30

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10 December 2019

2

1 reference

Europe PubMed Central

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10 December 2019

491-500

1 reference

Europe PubMed Central

PubMed publication ID

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10 December 2019

Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. 6. The first water-soluble ACAT inhibitor with lipid-regulating activity

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. CI-1011: an acyl sulfamate with unique cholesterol-lowering activity in animals fed noncholesterol-supplemented diets

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of Biliary Drainage on Individual Reactions in the Conversion of Cholesterol to Taurocholic Acid. Bile Acids and Steroids 180

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Potential bile acid precursors in plasma--possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in man

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased bile acid pool inhibits cholesterol 7 alpha-hydroxylase in cholesterol-fed rabbits

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclosporin A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxycholic acid synthesis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Bile Acid Synthesis in Man: Metabolism of 7α-Hydroxycholesterol-14C and 26-Hydroxycholesterol-3H

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of cholesterol metabolism in the dog. I. Effects of complete bile diversion and of cholesterol feeding on absorption, synthesis, accumulation, and excretion rates measured during life

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Unexpected inhibition of cholesterol 7 alpha-hydroxylase by cholesterol in New Zealand white and Watanabe heritable hyperlipidemic rabbits.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Dietary cholesterol and downregulation of cholesterol 7 alpha-hydroxylase and cholesterol absorption in African green monkeys

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of hepatic 7 alpha-hydroxylase expression and response to dietary cholesterol in the rat and hamster

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Ketoconazole blocks bile acid synthesis in hepatocyte monolayer cultures and in vivo in rat by inhibiting cholesterol 7 alpha-hydroxylase

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential feedback regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by rat bile acids in primary monolayer cultures of rat hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Cafestol, the cholesterol-raising factor in boiled coffee, suppresses bile acid synthesis by downregulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Cellular free cholesterol in Hep G2 cells is only partially available for down-regulation of low-density-lipoprotein receptor activity

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Enterohepatic circulation in the rat.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

A fluorimetric and enzymatic method for the estimation of serum total bile acids

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered lipid metabolism in apolipoprotein E-deficient mice does not affect cholesterol balance across the liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

46 Reversed-phase high-performance liquid chromatography assay of cholesterol 7α-hydroxylase

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of acyl-CoA: cholesterol acyltransferase in the metabolism of free cholesterol to cholesteryl esters or bile acids in primary cultures of rat hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Bile acid synthesis in hamster hepatocytes in primary culture: sources of cholesterol and comparison with other species

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

ACAT inhibitor HL-004 accelerates the regression of hypercholesterolemia in stroke-prone spontaneously hypertensive rats (SHRSP): stimulation of bile acid production by HL-004

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytes

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

CI-1011 lowers lipoprotein(a) and plasma cholesterol concentrations in chow-fed cynomolgus monkeys

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Secretion of Cholesterol-Rich Lipoproteins by Perfused Livers of Hypercholesterolemic Rats

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Cholesterol is required for secretion of very-low-density lipoprotein by rat liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Hepatic ACAT activity in African green monkeys is highly correlated to plasma LDL cholesteryl ester enrichment and coronary artery atherosclerosis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of lymphatic drainage on 7alpha-hydroxylation of cholesterol in rat liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

On the mechanism of stimulation of cholesterol 7 alpha-hydroxylase by dietary cholesterol.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510300230

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/HEP.510300230

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10421659%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10421659%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

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