(Q78066649)

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Oligodeoxynucleotides containing CpG motifs induce IL-12, IL-18 and IFN-gamma production in cells from allergic individuals and inhibit IgE synthesis in vitro

scientific article published on 01 July 1999

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10427997%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

Oligodeoxynucleotides containing CpG motifs induce IL-12, IL-18 and IFN-gamma production in cells from allergic individuals and inhibit IgE synthesis in vitro (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10427997%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

1

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10 December 2019

author name string

B Jahn-Schmid

2

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10 December 2019

D Maurer

3

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10 December 2019

D Kraft

4

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10 December 2019

C Ebner

5

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10 December 2019

publication date

1 July 1999

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10 December 2019

European Journal of Immunology

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10 December 2019

29

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10 December 2019

7

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10 December 2019

2344-2353

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10 December 2019

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma

1 reference

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Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants.

1 reference

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21 January 2018

CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity

1 reference

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Oligonucleotide adjuvants for T helper 1 (Th1)-specific vaccination

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21 January 2018

Bacterial DNA as an evolutionary conserved ligand signalling danger of infection to immune cells

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21 January 2018

CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants

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21 January 2018

Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock

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21 January 2018

Cloning of a new cytokine that induces IFN-gamma production by T cells

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21 January 2018

Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells

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21 January 2018

CpG motifs in bacterial DNA trigger direct B-cell activation

1 reference

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21 January 2018

Activation of human B cells by phosphorothioate oligodeoxynucleotides

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21 January 2018

DNA immunotherapeutics: new potential treatment modalities for allergic disease

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21 January 2018

Regulation of the development of type 2 T-helper cells in allergy

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21 January 2018

Prevalence of atopy and pollinosis in the adult population of Switzerland (SAPALDIA study). Swiss Study on Air Pollution and Lung Diseases in Adults

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21 January 2018

PROPHYLACTIC INOCULATION AGAINST HAY FEVER

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21 January 2018

Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs

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21 January 2018

The subclass nature and clinical significance of the IgG antibody response in patients undergoing allergen-specific immunotherapy

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21 January 2018

Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to allergen and shift from TH2 to TH1 in T-cell clones specific for Phl p 1, a major grass pollen allergen

1 reference

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21 January 2018

Role of interleukin 10 in specific immunotherapy

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21 January 2018

Interleukin 4 production by CD4+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type

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21 January 2018

Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma.

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21 January 2018

Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals

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21 January 2018

Dissection of immunoglobulin E and T lymphocyte reactivity of isoforms of the major birch pollen allergen Bet v 1: potential use of hypoallergenic isoforms for immunotherapy

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21 January 2018

Differences in clinical and immunologic reactivity of patients allergic to grass pollens and to multiple-pollen species. II. Efficacy of a double-blind, placebo-controlled, specific immunotherapy with standardized extracts

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21 January 2018

Regulation of IgE Synthesis

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21 January 2018

Effects of adjuvants on the immune response to allergens in a murine model of allergen inhalation: cholera toxin induces a Th1-like response to Bet v 1, the major birch pollen allergen

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21 January 2018

Bet v 1, the major birch pollen allergen, conjugated to crystalline bacterial cell surface proteins, expands allergen-specific T cells of the Th1/Th0 phenotype in vitro by induction of IL-12.

1 reference

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21 January 2018

DNA as an adjuvant: capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen

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CpG motifs as immune adjuvants

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Allergen-induced cytokine production in atopic disease and its relationship to disease severity

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The assay of interleukin 4 in the serum of normal subjects and atopic patients using a novel immunoassay

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Serum IgE level is negatively correlated with the ability of peripheral mononuclear cells to produce interferon gamma (IFNgamma): evidence of reduced expression of IFNgamma mRNA in atopic patients

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21 January 2018

Identifiers

10.1002/(SICI)1521-4141(199907)29:07<2344::AID-IMMU2344>3.0.CO;2-R

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release_m6anjzknnfgt7dklucivpxgdmu

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10427997%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

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