(Q78172673)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10462762%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

title

GPCR-Galpha fusion proteins: molecular analysis of receptor-G-protein coupling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10462762%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

author name string

R Seifert

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10462762%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

K Wenzel-Seifert

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10462762%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

B K Kobilka

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10462762%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

publication date

1 September 1999

1 reference

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Trends in Pharmacological Sciences

12 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10462762%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

volume

20

1 reference

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12 December 2019

issue

9

1 reference

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12 December 2019

page(s)

383-389

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10462762%20AND%20SRC:MED&resulttype=core&format=json

Cellular signaling by an agonist-activated receptor/Gs alpha fusion protein

12 December 2019

cites work

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7 January 2021

Human beta2-adrenergic receptor/GS alpha fusion protein, expressed in 2 ras-dependent murine carcinoma cell lines, prevents tumor growth in syngeneic mice

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7 January 2021

Different effects of Gsalpha splice variants on beta2-adrenoreceptor-mediated signaling. The Beta2-adrenoreceptor coupled to the long splice variant of Gsalpha has properties of a constitutively active receptor

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7 January 2021

Reconstitution of beta2-adrenoceptor-GTP-binding-protein interaction in Sf9 cells--high coupling efficiency in a beta2-adrenoceptor-G(s alpha) fusion protein

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7 January 2021

Restricting mobility of Gsalpha relative to the beta2-adrenoceptor enhances adenylate cyclase activity by reducing Gsalpha GTPase activity

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7 January 2021

Examining the efficiency of receptor/G-protein coupling with a cleavable beta2-adrenoceptor-gsalpha fusion protein

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7 January 2021

Effects of guanine, inosine, and xanthine nucleotides on beta(2)-adrenergic receptor/G(s) interactions: evidence for multiple receptor conformations

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7 January 2021

Measurement of agonist-induced guanine nucleotide turnover by the G-protein Gi1alpha when constrained within an alpha2A-adrenoceptor-Gi1alpha fusion protein

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7 January 2021

Measurement of agonist efficacy using an alpha2A-adrenoceptor-Gi1alpha fusion protein

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7 January 2021

Rescue of functional interactions between the alpha2A-adrenoreceptor and acylation-resistant forms of Gi1alpha by expressing the proteins from chimeric open reading frames.

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7 January 2021

Agonist occupation of an alpha2A-adrenoreceptor-Gi1alpha fusion protein results in activation of both receptor-linked and endogenous Gi proteins. Comparisons of their contributions to GTPase activity and signal transduction and analysis of receptor-

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7 January 2021

Quantitative analysis of a cysteine351glycine mutation in the G protein Gi1alpha: effect on alpha2A-adrenoceptor-Gi1alpha fusion protein activation

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7 January 2021

Loss of activation of Gs but not Gi following expression of an alpha2A-adrenoceptor-Gi1alpha fusion protein

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7 January 2021

Modulation of relative intrinsic activity of agonists at the alpha-2A adrenoceptor by mutation of residue 351 of G protein gi1alpha

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7 January 2021

Comparative analysis of the efficacy of A1 adenosine receptor activation of Gi/o alpha G proteins following coexpression of receptor and G protein and expression of A1 adenosine receptor-Gi/o alpha fusion proteins

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7 January 2021

Modulation of 5-HT1A receptor signalling by point-mutation of cysteine351 in the rat Galpha(o) protein.

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7 January 2021

Efficient signal transduction by a chimeric yeast-mammalian G protein alpha subunit Gpa1-Gsalpha covalently fused to the yeast receptor Ste2.

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7 January 2021

G proteins: transducers of receptor-generated signals

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7 January 2021

Receptor-effector coupling by G proteins

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7 January 2021

Adrenergic receptors as models for G protein-coupled receptors

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7 January 2021

Diversity and selectivity of receptor-G protein interaction

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7 January 2021

Differences between natural and recombinant G protein-coupled receptor systems with varying receptor/G protein stoichiometry

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7 January 2021

Membrane organization in G-protein mechanisms.

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7 January 2021

Partial agonists, full agonists, antagonists: dilemmas of definition

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7 January 2021

The elusive nature of intrinsic efficacy

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7 January 2021

G-protein diseases furnish a model for the turn-on switch

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7 January 2021

Mutagenesis of the beta2-Adrenergic Receptor: How Structure Elucidates Function

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7 January 2021

The C-terminus of the prostaglandin-E-receptor EP3 subtype is essential for activation of GTP-binding protein

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7 January 2021

Extensive Contact between Gi2 and N-Formyl Peptide Receptor of Human Neutrophils: Mapping of Binding Sites Using Receptor-Mimetic Peptides

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7 January 2021

G-Protein binding domains of the angiotensin II AT1A receptors mapped with synthetic peptides selected from the receptor sequence

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7 January 2021

Chimaeric G alpha proteins: their potential use in drug discovery

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7 January 2021

Activation and depalmitoylation of Gs alpha

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7 January 2021

Stimulation of beta-adrenergic receptors of S49 lymphoma cells redistributes the alpha subunit of the stimulatory G protein between cytosol and membranes

1 reference

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7 January 2021

Agonist-induced release of splice variants of the alpha subunit of the stimulatory G-protein from rat cardiac membranes

1 reference

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7 January 2021

Measurement of receptor-stimulated guanosine 5'-O-(gamma-thio)triphosphate binding by G proteins

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7 January 2021

Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes

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7 January 2021

Agonist-independent activation of Gz by the 5-hydroxytryptamine1A receptor co-expressed in Spodoptera frugiperda cells. Distinguishing inverse agonists from neutral antagonists

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7 January 2021

Human 5-HT1 receptor subtypes exhibit distinct G protein coupling behaviors in membranes from Sf9 cells

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7 January 2021

The transitory complex between photoexcited rhodopsin and transducin. Reciprocal interaction between the retinal site in rhodopsin and the nucleotide site in transducin.

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7 January 2021

The role of nucleoside-diphosphate kinase reactions in G protein activation of NADPH oxidase by guanine and adenine nucleotides

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7 January 2021

High constitutive activity of the human formyl peptide receptor

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7 January 2021

G proteins endogenously expressed in Sf 9 cells: interactions with mammalian histamine receptors

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7 January 2021

The carboxy-terminal segment of the yeast alpha-factor receptor is a regulatory domain

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7 January 2021

Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor

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7 January 2021

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

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7 January 2021

A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade

1 reference

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7 January 2021

10.1016/S0165-6147(99)01368-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10462762%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

1 reference