(Q78255498)

English

Dose-dependence and repeated-dose studies for receptor/gene-mediated pharmacodynamics of methylprednisolone on glucocorticoid receptor down-regulation and tyrosine aminotransferase induction in rat liver

scientific article published on 01 December 1998

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10485078%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Dose-dependence and repeated-dose studies for receptor/gene-mediated pharmacodynamics of methylprednisolone on glucocorticoid receptor down-regulation and tyrosine aminotransferase induction in rat liver (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10485078%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

methylprednisolone

1 reference

based on heuristic

inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

author name string

Y N Sun

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10485078%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

D C DuBois

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10485078%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

R R Almon

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10485078%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

N A Pyszczynski

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10485078%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

W J Jusko

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10485078%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

publication date

1 December 1998

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10485078%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Journal of Pharmacokinetics and Pharmacodynamics

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10485078%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

26

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10485078%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10485078%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

619-648

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10485078%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

https://scigraph.springernature.com/pub.10.1023/a:1020746822634

0 references

Pharmacodynamic models of nitroglycerin-induced hemodynamic tolerance in experimental heart failure.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the protein-protein interactions determining the heat shock protein (hsp90.hsp70.hsp56) heterocomplex

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of glucocorticoid receptor protein and mRNA levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transit compartments versus gamma distribution function to model signal transduction processes in pharmacodynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor-mediated methylprednisolone pharmacodynamics in rats: steroid-induced receptor down-regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoid therapy for immune-mediated diseases: basic and clinical correlates

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticosteroid receptor dimerization investigated by analysis of receptor binding to glucocorticosteroid responsive elements using a monomer-dimer equilibrium model

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homologous down regulation of the glucocorticoid receptor: the molecular machinery.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacoimmunodynamics of methylprednisolone: trafficking of helper T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extended least squares nonlinear regression: a possible solution to the "choice of weights" problem in analysis of individual pharmacokinetic data

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for kinetically distinct forms of corticosteroid 11 beta-dehydrogenase in rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro RNA synthesis with SP6 RNA polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug- or hormone-induced adaptation: model of adrenergic hypersensitivity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of methylprednisolone and its sodium succinate prodrug in vivo and in perfused liver of rats: nonlinear and sequential first-pass elimination

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic/Pharmacodynamic models for corticosteroid receptor down-regulation and glutamine synthetase induction in rat skeletal muscle by a Receptor/Gene-mediated mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Testing for the equality of area under the curves when using destructive measurement techniques

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molar quantification of specific messenger ribonucleic acid expression in northern hybridization using cRNA standards

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of an AUUUA-specific messenger RNA binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamic modeling of cortisol suppression from fluocortolone

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticosteroid effects in skeletal muscle: gene induction/receptor autoregulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The poly(A)-poly(A)-binding protein complex is a major determinant of mRNA stability in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of reversible metabolic systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noncompartmental Determination of the Steady‐State Volume of Distribution

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Second generation model for prednisolone pharmacodynamics in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticosteroids: clinical pharmacology and therapeutic use.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of four basic models of indirect pharmacodynamic responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of glucocorticoid receptor phosphorylation in intact cells. Evidence for hormone-induced hyperphosphorylation after activation and recycling of hyperphosphorylated receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Third-generation model for corticosteroid pharmacodynamics: roles of glucocorticoid receptor mRNA and tyrosine aminotransferase mRNA in rat liver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoid-receptor complexes in rat thymus cells. Rapid kinetic behavior and a cyclic model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor-mediated pharmacodynamics of prednisolone in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of glucocorticoid unresponsive cell variants using a mouse glucocorticoid receptor complementary DNA clone

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolactin release after remoxipride by an integrated pharmacokinetic-pharmacodynamic model with intra- and interindividual aspects

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Convergence of direct and indirect pharmacodynamic response models

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dexamethasone regulates glutamine synthetase expression in rat skeletal muscles

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of glucocorticoid receptor expression: evidence for transcriptional and posttranslational mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic-pharmacodynamic modeling of caffeine: tolerance to pressor effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Applying Bailer's method for AUC confidence intervals to sparse sampling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fourth-generation model for corticosteroid pharmacodynamics: a model for methylprednisolone effects on receptor/gene-mediated glucocorticoid receptor down-regulation and tyrosine aminotransferase induction in rat liver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappa B and Rel: participants in a multiform transcriptional regulatory system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of androgen administration on phallic androgen receptor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamic modeling of furosemide tolerance after multiple intravenous administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of troleandomycin on methylprednisolone elimination

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylprednisolone disposition in rabbits. Analysis, prodrug conversion, reversible metabolism, and comparison with man

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioavailability and nonlinear disposition of methylprednisolone and methylprednisone in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential dynamics of receptor down-regulation and tyrosine aminotransferase induction following glucocorticoid treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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