(Q78498262)

English

Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs

scientific article published on 01 October 2002

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

1 reference

based on heuristic

inferred from title

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Christopher P. Landowski

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

author name string

Duxin Sun

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Hans Lennernas

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Jeffery L Barnett

4

1 reference

Europe PubMed Central

PubMed publication ID

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14 December 2019

David Foster

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

David Fleisher

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Kyung-Dall Lee

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Gordon L Amidon

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

publication date

1 October 2002

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Europe PubMed Central

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14 December 2019

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

19

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

10

1 reference

Europe PubMed Central

PubMed publication ID

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14 December 2019

1400-1416

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Link between drug absorption solubility and permeability measurements in Caco-2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predicting fraction dose absorbed in humans using a macroscopic mass balance approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a polarized efflux system in CACO-2 cells capable of modulating cyclosporin A transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man--fact or myth

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHO/hPEPT1 cells overexpressing the human peptide transporter (hPEPT1) as an alternative in vitro model for peptidomimetic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro permeability through caco-2 cells is not quantitatively predictive of in vivo absorption for peptide-like drugs absorbed via the dipeptide transporter system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human intestinal permeability of piroxicam, propranolol, phenylalanine, and PEG 400 determined by jejunal perfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suitability of enalapril as a probe of the dipeptide transporter system: in vitro and in vivo studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimating human oral fraction dose absorbed: a correlation using rat intestinal membrane permeability for passive and carrier-mediated compounds.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the major metabolites of verapamil as substrates and inhibitors of P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose transporter Glut3 is targeted to secretory vesicles in neurons and PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlating partitioning and caco-2 cell permeability of structurally diverse small molecular weight compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passive and carrier-mediated intestinal absorption components of two angiotensin converting enzyme (ACE) inhibitor prodrugs in rats: enalapril and fosinopril

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of an alpha-amino group on H+ -dependent transepithelial transport of cephalosporins in Caco-2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of intestinal peptide transport with a protein related to the cadherin superfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the oral absorption of some beta-lactams: effect of the alpha-amino side chain group

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of drug absorption with molecular surface properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of structural modifications on the intestinal permeability of angiotensin II receptor antagonists and the correlation of in vitro, in situ, and in vivo absorption

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive inhibition of glycylsarcosine transport by enalapril in rabbit renal brush border membrane vesicles: interaction of ACE inhibitors with high-affinity H+/peptide symporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal absorption of amino acid derivatives: importance of the free alpha-amino group

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of drug permeation across Caco-2 monolayer: implication for predicting in vivo drug absorption.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human intestinal permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human jejunal permeability of two polar drugs: cimetidine and ranitidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in situ absorption of SDZ-RAD using a human intestinal cell line (Caco-2) and a single pass perfusion model in rats: comparison with rapamycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of human intestinal oligopeptide transporter in mammalian cells via adenoviral transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDCK (Madin-Darby canine kidney) cells: A tool for membrane permeability screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HT29-MTX/Caco-2 cocultures as an in vitro model for the intestinal epithelium: in vitro-in vivo correlation with permeability data from rats and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between epithelial cell permeability of cephalexin and expression of intestinal oligopeptide transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prodrug approach for alphaIIbbeta3-peptidomimetic antagonists to enhance their transport in monolayers of a human intestinal cell line (Caco-2): comparison of in vitro and in vivo data

1 reference

https://pubmed.ncbi.nlm.nih.gov/12425456

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1020483911355

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12425456%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

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