(Q79303236)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623946%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Central role of mitochondria and p53 in Fas-mediated apoptosis of rheumatoid synovial fibroblasts (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623946%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://api.crossref.org/works/10.1093/RHEUMATOLOGY/KEH039

3 April 2024

author name string

K. Itoh

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623946

3 April 2024

H. Hase

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623946

3 April 2024

H. Kojima

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623946

3 April 2024

K. Saotome

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623946

3 April 2024

K. Nishioka

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623946

3 April 2024

T. Kobata

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623946

3 April 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14623946

3 April 2024

publication date

17 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623946%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

21 December 2019

published in

Rheumatology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623946%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

volume

43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623946%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623946%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

277-285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623946%20AND%20SRC:MED&resulttype=core&format=json

Rheumatoid arthritis. Pathophysiology and implications for therapy

21 December 2019

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Two CD95 (APO-1/Fas) signaling pathways

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

3 April 2024

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Tumor necrosis factor alpha regulation of the FAS-mediated apoptosis-signaling pathway in synovial cells

3 April 2024

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Fas-associated death domain protein is a Fas-mediated apoptosis modulator in synoviocytes

3 April 2024

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Differential regulation of Fas-mediated apoptosis of rheumatoid synoviocytes by tumor necrosis factor alpha and basic fibroblast growth factor is associated with the expression of apoptosis-related molecules

3 April 2024

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Defying death after DNA damage.

3 April 2024

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3 April 2024

p53: death star

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A matter of life and cell death

3 April 2024

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3 April 2024

Surfing the p53 network

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p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

3 April 2024

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p53 overexpression in synovial tissue from patients with early and longstanding rheumatoid arthritis compared with patients with reactive arthritis and osteoarthritis

3 April 2024

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Apoptosis in rheumatoid arthritis--expression of Fas, Fas-L, p53, and Bcl-2 in rheumatoid synovial tissues

3 April 2024

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Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium.

3 April 2024

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Mutations of the p53 tumour suppressor gene in erosive rheumatoid synovial tissue

3 April 2024

29

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Analysis of the p53 tumor suppressor gene in rheumatoid arthritis synovial fibroblasts

3 April 2024

30

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Analysis of p53 tumour suppressor gene somatic mutations in rheumatoid arthritis synovium

3 April 2024

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Analysis of the p53 tumor suppressor gene in rheumatoid arthritis synovial fibroblasts

3 April 2024

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Regulation of rheumatoid synoviocyte proliferation by endogenous p53 induction

3 April 2024

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p53 in rheumatoid arthritis: friend or foe?

3 April 2024

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Regional analysis of p53 mutations in rheumatoid arthritis synovium

3 April 2024

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Establishment and characterization of synovial cell clones with integrated human T-cell leukemia virus type-I.

3 April 2024

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CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation

3 April 2024

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p53 negatively regulates intestinal immunity by delaying mucosal T cell cycling

3 April 2024

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

3 April 2024

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

3 April 2024

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1 reference

https://api.crossref.org/works/10.1093/RHEUMATOLOGY/KEH039

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

3 April 2024

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Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

3 April 2024

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Low levels of apoptosis and high FLIP expression in early rheumatoid arthritis synovium

3 April 2024

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

3 April 2024

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Apoptosis in rheumatoid arthritis--expression of Fas, Fas-L, p53, and Bcl-2 in rheumatoid synovial tissues

3 April 2024

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Regulation of joint destruction and inflammation by p53 in collagen-induced arthritis

3 April 2024

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Invasiveness of synovial fibroblasts is regulated by p53 in the SCID mouse in vivo model of cartilage invasion

3 April 2024

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Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

3 April 2024

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p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

3 April 2024

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Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis

3 April 2024

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The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat

3 April 2024

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Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

3 April 2024

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Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis

3 April 2024

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Daxx, a novel Fas-binding protein that activates JNK and apoptosis

3 April 2024

55

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Fas induces cytoplasmic apoptotic responses and activation of the MKK7-JNK/SAPK and MKK6-p38 pathways independent of CPP32-like proteases.

3 April 2024

56

1 reference

https://api.crossref.org/works/10.1093/RHEUMATOLOGY/KEH039

MEKK1/JNK signaling stabilizes and activates p53.

3 April 2024

57

1 reference

https://api.crossref.org/works/10.1093/RHEUMATOLOGY/KEH039

Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.

3 April 2024

58

1 reference

https://api.crossref.org/works/10.1093/RHEUMATOLOGY/KEH039

Gene transfer of p53 to arthritic joints stimulates synovial apoptosis and inhibits inflammation

3 April 2024

59

1 reference

https://api.crossref.org/works/10.1093/RHEUMATOLOGY/KEH039

3 April 2024

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14623946%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference