(Q79415986)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17154260%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

title

FTY720 enhances the activation-induced apoptosis of donor T cells and modulates graft-versus-host disease (English)

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22 December 2019

1

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22 December 2019

Takanori Teshima

8

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22 December 2019

author name string

Shoji Asakura

2

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22 December 2019

Ken-ichi Matsuoka

3

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22 December 2019

Yukimi Sakoda

4

1 reference

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22 December 2019

Motoko Koyama

5

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22 December 2019

Kazutoshi Aoyama

6

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22 December 2019

Mitsune Tanimoto

7

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22 December 2019

publication date

1 January 2007

1 reference

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European Journal of Immunology

22 December 2019

published in

1 reference

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22 December 2019

volume

37

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22 December 2019

issue

1

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22 December 2019

page(s)

271-281

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Prevention of graft versus host disease by inactivation of host antigen-presenting cells

22 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Acute graft-versus-host disease does not require alloantigen expression on host epithelium

1 reference

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7 January 2021

Negative selection of T cells causing lethal graft-versus-host disease across minor histocompatibility barriers. Role of the H-2 complex

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7 January 2021

Homeostasis and self-tolerance in the immune system: turning lymphocytes off.

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7 January 2021

Activation-induced death of mature T cells in the regulation of immune responses

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7 January 2021

The fate of donor T-cell receptor transgenic T cells with known host antigen specificity in a graft-versus-host disease model

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Donor-derived interferon gamma is required for inhibition of acute graft-versus-host disease by interleukin 12.

1 reference

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7 January 2021

The duration of antigenic stimulation determines the fate of naive and effector T cells.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment

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7 January 2021

Repeated stimulation of CD4 effector T cells can limit their protective function

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7 January 2021

Potent immunosuppressants, 2-alkyl-2-aminopropane-1,3-diols

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7 January 2021

The immune modulator FTY720 targets sphingosine 1-phosphate receptors

1 reference

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7 January 2021

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

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7 January 2021

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

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7 January 2021

Prophylaxis of acute renal allograft rejection using FTY720 in combination with subtherapeutic doses of cyclosporine

1 reference

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7 January 2021

Graft-versus-host disease can be separated from graft-versus-lymphoma effects by control of lymphocyte trafficking with FTY720.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Interleukin-11 promotes T cell polarization and prevents acute graft-versus-host disease after allogeneic bone marrow transplantation.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Understanding the alloresponse: new approaches to graft-versus-host disease prevention.

1 reference

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7 January 2021

Sphingosine-1-phosphate receptor agonism impairs the efficiency of the local immune response by altering trafficking of naive and antigen-activated CD4+ T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Immunosuppressive activity of FTY720, sphingosine 1-phosphate receptor agonist: II. Effect of FTY720 and FTY720-phosphate on host-versus-graft and graft-versus-host reaction in mice

1 reference

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7 January 2021

Transient T cell accumulation in lymph nodes and sustained lymphopenia in mice treated with FTY720.

1 reference

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7 January 2021

Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation

1 reference

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7 January 2021

A novel immunosuppressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation

1 reference

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7 January 2021

FTY720: altered lymphocyte traffic results in allograft protection

1 reference

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7 January 2021

Individuality: the barrier to optimal immunosuppression

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

FTY720 does not abrogate acute graft-versus-host disease in the dog leukocyte antigennonidentical unrelated canine model1

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

The S1P-analog FTY720 differentially modulates T-cell homing via HEV: T-cell-expressed S1P1 amplifies integrin activation in peripheral lymph nodes but not in Peyer patches.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid organ transit

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Host dendritic cells alone are sufficient to initiate acute graft-versus-host disease

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Identification and monitoring of graft-versus-host specific T-cell clone in stem cell transplantation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Interleukin-18 regulates acute graft-versus-host disease by enhancing Fas-mediated donor T cell apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Role of the passive apoptotic pathway in graft-versus-host disease

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Novel insights into the mechanism of action of FTY720 in a transgenic model of allograft rejection: implications for therapy of chronic rejection.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Opposing roles of interferon-gamma on CD4+ T cell-mediated graft-versus-host disease: effects of conditioning

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Murine acute graft-versus-host disease can be prevented by depletion of alloreactive T lymphocytes using activation-induced cell death

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Ex vivo depletion of alloreactive cells based on CFSE dye dilution, activation antigen selection, and dendritic cell stimulation

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7 January 2021

Efficient depletion of alloreactive donor T lymphocytes based on expression of two activation-induced antigens (CD25 and CD69).

1 reference

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7 January 2021

Selective depletion of major and minor histocompatibility antigen reactive T cells: towards prevention of acute graft-versus-host disease

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7 January 2021

Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of Th1 cytokines

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7 January 2021

Paradoxical effects of interleukin-18 on the severity of acute graft-versus-host disease mediated by CD4+ and CD8+ T-cell subsets after experimental allogeneic bone marrow transplantation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Stimulation with 4-1BB (CD137) inhibits chronic graft-versus-host disease by inducing activation-induced cell death of donor CD4+ T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

A novel apoptosis-inducing anti-PSGL-1 antibody for T cell-mediated diseases.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

CD28 ligation induces transplantation tolerance by IFN-gamma-dependent depletion of T cells that recognize alloantigens

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

A phase II multicenter study of visilizumab, humanized anti-CD3 antibody, to treat steroid-refractory acute graft-versus-host disease

1 reference

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7 January 2021

FTY720, a novel immunomodulator: efficacy and safety results from the first phase 2A study in de novo renal transplantation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Effect of FTY720 on chronic cyclosporine nephropathy in rats

1 reference

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7 January 2021

The sphingosine 1-phosphate receptor agonist FTY720 supports CXCR4-dependent migration and bone marrow homing of human CD34+ progenitor cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Long-term T cell fitness and proliferation is driven by AMPK-dependent regulation of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Fetal tolerance to maternal antigens improves the outcome of allogeneic bone marrow transplantation by a CD4+ CD25+ T-cell-dependent mechanism

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Cutting edge: amelioration of kidney disease in a transgenic mouse model of lupus nephritis by administration of the caspase inhibitor carbobenzoxy-valyl-alanyl-aspartyl-(beta-o-methyl)-fluoromethylketone

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Stimulation of Host NKT Cells by Synthetic Glycolipid Regulates Acute Graft-versus-Host Disease by Inducing Th2 Polarization of Donor T Cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200636123

7 January 2021

Identifiers

DOI

10.1002/EJI.200636123

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17154260%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference